J Fluoresc
2
+
selective fluorescent sensor for Cu based on two different ap-
proaches. Org Lett 12:3852–3855
recognized by the Bnaked eye^. The probe Py shows high
selectivity, sensitivity, reversibility and low cytotoxicity. The
1
5. Kang H, Fan C, Xu H, Liu G, Pu S (2018) A highly selective
3
+
reaction mechanism between probe Py and Fe were per-
formed using DFT calculation. Importantly, the probe Py
2+
3+
fluorescence switch for Cu and Fe based on a new diarylethene
with a triazole-linked rhodamine 6G unit. Tetrahedron 74:4390–
3
+
4
399
was used to sense Fe in cells successfully. These features
will make it more potential for biological applications.
1
6. Qin JC, Yang ZY, Wang GQ, Li CR (2015) FRET-based
3
+
rhodamine–coumarin conjugate as a Fe selective ratiometric
fluorescent sensor in aqueous media. Tetrahedron Lett 56:5024–
Acknowledgements We gratefully acknowledge financial support from
the National Natural Science Foundation of China (Grant no.21042002).
5
029
1
1
1
2
7. You Q-H, Huang H-B, Zhuang Z-X, Wang X-R, Chan W-H (2016)
A new rhodamine-based fluorescent probe for the discrimination of
3
+
2+
Publisher’s Note Springer Nature remains neutral with regard to jurisdic-
tional claims in published maps and institutional affiliations.
Fe from Fe . Bull Kor Chem Soc 37:1772–1777
8. Ge F, Ye H, Zhang H, Zhao B-X (2013) A novel ratiometric probe
based on rhodamine B and coumarin for selective recognition of
Fe(III) in aqueous solution. Dyes Pigments 99:661–665
9. Zhao J, Gao Q, Zhang F, Sun W, Bai Y (2016) Two colorimetric
References
3
+
fluorescent probes for detection Fe : synthesis, characterization
and theoretical calculations. J Lumin 180:278–286
1
.
Zhang Y, Wang Y-T, Kang X-X, Ge M, Feng H-Y, Han J, Wang D-
H, Zhao D-Z (2018) Azobenzene disperse dye-based colorimetric
probe for naked eye detection of Cu in aqueous media: spectral
properties, theoretical insights, and applications. J Photoch
Photobio A 356:652–660
0. Chen X, Sun W, Bai Y, Zhang F, Zhao J, Ding X (2018) Novel
rhodamine Schiff base type naked-eye fluorescent probe for sensing
Fe(3+) and the application in cell. Spectrochim Acta A Mol Biomol
Spectrosc 191:566–572
1. Zhang J, Zhang L, Wei Y, Chao J, Shuang S, Cai Z, Dong C (2014)
A selectively rhodamine-based colorimetric probe for detecting
copper(II) ion. Spectrochim Acta A Mol Biomol Spectrosc 122:
2
+
2
2
.
.
Ozdemir M, Zhang Y, Guo M (2018) A highly selective Boff-on^
fluorescent sensor for subcellular visualization of labile iron(III) in
living cells. Inorg Chem Commun 90:73–77
1
91–197
3
Wang J, Zhang D, Liu Y, Ding P, Wang C, Ye Y, Zhao Y (2014) A
3+
22. Hao Z, Fan J, Jing L, Hu M, Cao J, Jing W, Li H, Liu X, Peng X
N-stablization rhodamine-based fluorescent chemosensor for Fe
2+
(
2012) Optical Cu probe bearing an 8-hydroxyquinoline subunit:
in aqueous solution and its application in bioimaging. Sensors
Actuators B Chem 191:344–350
high sensitivity and large fluorescence enhancement. Talanta 93:55
3. Bao X, Cao X, Nie X, Xu Y, Guo W, Zhou B, Zhang L, Liao H,
2
4
.
Zhu C, Wang M, Qiu L, Hao S, Li K, Guo Z, He W (2018) A
3+
3+
Pang T (2015) A new selective fluorescent chemical sensor for Fe
mitochondria-targeting fluorescent Fe probe and its application
3+
based on rhodamine B and a 1,4,7,10-tetraoxa-13-
azacyclopentadecane conjugate and its imaging in living cells.
Sensors Actuators B Chem 208:54–66
in labile Fe monitoring via imaging and flow cytometry. Dyes
Pigments 157:328–333
5
.
.
Yang Z, Bai X, Ma S, Liu X, Zhao S, Yang Z (2017) A benzoxazole
3
+
24. Li Z, Zhao JL, Wu YT, Mu L, Zeng X, Jin Z, Wei G, Xie N,
Redshaw C (2017) Highly selective recognition of Al(3+) and
I(−) ions using a bi-functional fluorescent probe. Org Biomol
Chem 15:8627–8633
25. Ruan Q, Mu L, Zeng X, Zhao JL, Zeng L, Chen ZM, Yang C, Wei
G, Redshaw C (2018) A three-dimensional (time, wavelength and
intensity) functioning fluorescent probe for the selective
recognition/discrimination of cu(2+), hg(2+), Fe(3+) and F(−) ions.
Dalton Trans 47:3674–3678
functionalized fluorescent probe for selective Fe detection and
intracellular imaging in living cells. Anal Methods 9:18–22
Sen S, Sarkar S, Chattopadhyay B, Moirangthem A, Basu A, Dhara
K, Chattopadhyay P (2012) A ratiometric fluorescent chemosensor
6
2
+
3+
for iron: discrimination of Fe and Fe and living cell application.
Analyst 137:3335–3342
7.
8.
9.
Long L, Zhou L, Lin W, Meng S, Gong A, Chi Z (2014) A
ratiometric fluorescent probe for iron(III) and its application for
detection of iron(III) in human blood serum. Anal Chim Acta
2
6. Li X, Yin Y, Deng J, Zhong H, Tang J, Chen Z, Yang L, Ma LJ
8
12:145–151
Bao X, Shi J, Nie X, Zhou B, Wang X, Zhang L, Liao H, Pang T
2014) A new rhodamine B-based 'on-off' chemical sensor with
(
)
2016) A solvent-dependent fluorescent detection method for Fe(3+
and hg(2+) based on a rhodamine B derivative. Talanta 154:329–
(
3
34
high selectivity and sensitivity toward Fe(3+) and its imaging in
living cells. Bioorg Med Chem 22:4826–4835
Jeong Y, Yoon J (2012) Recent progress on fluorescent
chemosensors for metal ions. Inorg Chim Acta 381:2–14
2
2
7. OuYang H, Gao Y, Yuan Y (2013) A highly selective rhodamine-
3+
based optical–electrochemical multichannel chemosensor for Fe .
Tetrahedron Lett 54:2964–2966 26
8. Chai M, Zhang D, Wang M, Hong H, Ye Y, Zhao Y (2012) Four
1
0. Xu H, Ding H, Li G, Fan C, Liu G, Pu S (2017) A highly selective
3+
3+
rhodamine B-based fluorescent chemosensor for Fe in aqueous
fluorescent chemosensor for Fe based on a new diarylethene with
solution. Sensors Actuators B Chem 174:231–236
a rhodamine 6G unit. RSC Adv 7:29827–29834
1
1. Yang Y, Wang X, Cui Q, Cao Q, Li L (2016) Self-assembly of
29. Liu Y, Shen R, Ru J, Yao X, Yang Y, Liu H, Tang X, Bai D, Zhang
G, Liu W (2016) A reversible rhodamine 6G-based fluorescence
fluorescent organic nanoparticles for Iron(III) sensing and cellular
imaging. ACS Appl Mater Interfaces 8:7440–7448
3
+
turn-on probe for Fe in water and its application in living cell
imaging. RSC Adv 6:111754–111759
1
2. Zheng M, Tan H, Xie Z, Zhang L, Jing X, Sun Z (2013) Fast
response and high sensitivity europium metal organic framework
30. Kagit R, Yildirim M, Ozay O, Yesilot S, Ozay H (2014)
Phosphazene based multicentered naked-eye fluorescent sensor
3
+
fluorescent probe with chelating Terpyridine sites for Fe . ACS
Appl Mater Interfaces 5:1078–1083
3+
with high selectivity for Fe ions. Inorg Chem 53:2144–2151
1
1
3. Pires MM, Chmielewski J (2008) Fluorescence imaging of cellular
glutathione using a latent rhodamine. Org Lett 10:837–840
4. Zhang JF, Zhou Y, Yoon J, Kim Y, Kim SJ, Kim JS (2010)
Naphthalimide modified rhodamine derivative: Ratiometric and
31. Yan L, Yang M, Leng X, Zhang M, Long Y, Yang B (2016) A new
3
+
dual-function fluorescent probe of Fe for bioimaging and probe-
3
+
−
Fe complex for selective detection of CN . Tetrahedron 72:4361–
4367