N-Bromosuccinimide Synthetic route
ConditionsConditions | Yield |
---|
With hydrogenchloride; sodium chlorite; sodium bromide In water at 0 - 25℃; for 1.5h; Temperature; | 96% |
With sodium bromate; sulfuric acid; hydrogen bromide In water for 0.166667h; Ambient temperature; | 95% |
With [bis(acetoxy)iodo]benzene In tetrachloromethane at 20℃; Solvent; | 94% |
ConditionsConditions | Yield |
---|
With tetraethylammonium bromide halogen exchange durin complex formation between an N-halogensuccinimide and quaternary ammonium halide; | |
With water; sodium bromide | |
- 82815-39-2
benzotelluracyclopentane bromide succinimide
B
1,1-dibromo-3,4-benzo-1-telluracyclopentane
ConditionsConditions | Yield |
---|
With bromine Te-N cleavage; | |
furan-2,3,5(4H)-trione pyridine (1:1)
- hypobromous acid
hypobromous acid
ConditionsConditions | Yield |
---|
With bromine Equilibrium constant; | |
2-(4-methylphenyl)-2-(N-bromo-p-toluene-sulfonamide)-1-bromo-ethane
B
2-bromo-1-(4-methylphenyl)-1-(p-toluenesulfonamido)ethane
C21H16BrS(1+)*C4H4NO2(1-)
ConditionsConditions | Yield |
---|
In dichloromethane-d2 at 22℃; Equilibrium constant; Inert atmosphere; Schlenk technique; | |
N-Bromosuccinimide Chemical Properties
Molecular Structure :
IUPAC Name: 1-bromopyrrolidine-2,5-dione
Empirical Formula: C4H4BrNO2
Molecular Weight: 177.9841
Product Categories: Nitrogen cyclic compounds; Medical Intermediates; Biochemistry; Bromination; Halogenation; N-Substituted Maleimides, Succinimides & Phthalimides; N-Substituted Succinimides; Reagents for Oligosaccharide Synthesis; Synthetic Organic Chemistry
Melting Point: 175-180 °C (dec.)(lit.)
Storage temperature: 0-6 °C
Sensitive: Moisture Sensitive
Stability: Stable. Incompatible with strong oxidizing agents, halogenated hydrocarbons.
Index of Refraction: 1.606
Surface Tension: 67.8 dyne/cm
Density: 2.042 g/cm3
Flash Point: 87.7 °C
Enthalpy of Vaporization: 45.79 kJ/mol
Boiling Point: 221.4 °C at 760 mmHg
Vapour Pressure of N-Bromosuccinimide (CAS NO.128-08-5): 0.107 mmHg at 25 °C
N-Bromosuccinimide Uses
N-Bromosuccinimide (CAS NO.128-08-5) is a chemical reagent which is used in radical substitution and electrophilic addition reactions in organic chemistry.It also can be considered a convenient source of cationic bromine.
N-Bromosuccinimide Safety Profile
Hazard Codes C,Xn
Risk Statements 22-34-36/37/38
R22:Harmful if swallowed.
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36/37/39-45-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39:Wear suitable gloves and eye/face protection.
N-Bromosuccinimide Specification
N-Bromosuccinimide (CAS NO.128-08-5), its Synonyms are 2,5-Pyrrolidinedione, 1-bromo- ; 1-Bromo-2,5-pyrrolidinedione ; Akos bbs-00004413 ; Bromosuccinimide ; Bromosuccinimide-n;succinimide, N-bromo- ; Succinbromide ; Succinbromimide . It is white to light yellow crystalline powder.