Trimethylsilyl tert-butyl peroxide

Base Information

• Chemical Name: Trimethylsilyl tert-butyl peroxide
• CAS No.: 3965-63-7
• Deprecated CAS: 42169-77-7
• Molecular Formula: C7H18 O2 Si
• Molecular Weight: 162.304
• Hs Code.: 2931900090
• European Community (EC) Number: 223-579-3
• UNII: 88SWR3574E
• DSSTox Substance ID: DTXSID9063249
• Nikkaji Number: J57.799E
• Wikidata: Q81990602
• Mol file: 3965-63-7.mol

Synonyms:Trimethylsilyl tert-butyl peroxide;3965-63-7;tert-butylperoxy(trimethyl)silane;Silane, [(1,1-dimethylethyl)dioxy]trimethyl-;EINECS 223-579-3;Peroxide, 1,1-dimethylethyl trimethylsilyl;Silane, ((1,1-dimethylethyl)dioxy)trimethyl-;88SWR3574E;tert-Butyl hydroperoxide, TMS derivative;((1,1-Dimethylethyl)dioxy)trimethylsilane;[(1,1-dimethylethyl)dioxy]trimethylsilane;t-butylperoxytrimethylsilane;SCHEMBL388565;UNII-88SWR3574E;t-butyl trimethylsilyl peroxide;C7-H18-O2-Si;DTXSID9063249;(tert-Butylperoxy)(trimethyl)silane #;AKOS006346699;TERT-BUTYL TRIMETHYLSILYL PEROXIDE;PEROXIDE, TERT-BUTYL TRIMETHYLSILYL;TERT-BUTYLTRIMETHYLSILYLPEROXIDE ~80%;1,1-DIMETHYLETHYL TRIMETHYLSILYL PEROXIDE

Chemical Property of Trimethylsilyl tert-butyl peroxide

Chemical Property:

• Vapor Pressure: 18mmHg at 25°C
• Boiling Point: 120.8°Cat760mmHg
• Flash Point: 9.3°C
• PSA: 18.46000
• Density: 0.842g/cm³
• LogP: 2.56800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 162.107606347
• Heavy Atom Count: 10
• Complexity: 99.2

Purity/Quality:

98%Min ^*data from raw suppliers

O-TRIMETHYLSILYL-TERT-BUTYL PEROXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 8-11-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OO[Si](C)(C)C

Technology Process of Trimethylsilyl tert-butyl peroxide

There total 11 articles about Trimethylsilyl tert-butyl peroxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

tert.-butylhydroperoxide (75-91-2) + bis-(trimethylsilyl)acetamide (17879-45-7) → tert-butylperoxytrimethylsilane (3965-63-7)

Guidance literature:

at 4 - 20 ℃; for 24h;

DOI:10.1039/c4ob01837k

Reference yield: 35.0%

tert.-butylhydroperoxide (75-91-2) + 1-(Trimethylsilyl)imidazole (18156-74-6) → tert-butylperoxytrimethylsilane (3965-63-7)

Guidance literature:

In dichloromethane; pentane; for 48h; Ambient temperature;

Reference yield:

tert.-butylhydroperoxide (75-91-2) + trimethylsilyl cyanide (7677-24-9) → tert-butylperoxytrimethylsilane (3965-63-7) + hydrogen cyanide (74-90-8)

Guidance literature:

In chloroform-d1; water; at 20 ℃; for 0.5h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.9b01607

upstream raw materials:

tert.-butylhydroperoxide

chloro-trimethyl-silane

1,1,1,3,3,3-hexamethyl-disilazane

lithium tert-butyl hydroperoxide

Downstream raw materials:

1,1-bis(t-butyldioxy)-3-phenylpropane

[bis(tert-butylperoxy)methyl]benzene

1-(Bis-tert-butylperoxy-methyl)-2-bromo-benzene

(2-tert-Butylperoxy-2-methoxy-ethyl)-benzene

Refernces

• 1、 Radzikowska, Ewa,Baraniak, Janina. "Synthesis of PS/PO-chimeric oligonucleotides using mixed oxathiaphospholane and phosphoramidite chemistry". . p. 269 - 276. Retrieved 2015.
• 2、 Krawczyk, Tomasz,Zalewski, Mariusz,Szo?tysik, Rafa?,Korytkowska-Wa?ach, Anna. "Determination of silyl peroxides by ultra-performance liquid chromatography/electrospray ionisation mass spectrometry". . p. 2040 - 2046. Retrieved 2018/11/10.