3-Phenylpropanoic acid trimethylsilyl ester

Base Information

• Chemical Name: 3-Phenylpropanoic acid trimethylsilyl ester
• CAS No.: 21273-15-4
• Molecular Formula: C12H18O2Si
• Molecular Weight: 222.359
• Hs Code.: 2931900090
• Mol file: 21273-15-4.mol

Synonyms:Benzenepropanoic acid,trimethylsilyl ester;Hydrocinnamic acid,trimethylsilyl ester;3-Phenylpropanoic acid trimethylsilyl ester;

Chemical Property of 3-Phenylpropanoic acid trimethylsilyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 2.99730

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Phenylpropanoic acid trimethylsilyl ester

There total 5 articles about 3-Phenylpropanoic acid trimethylsilyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + 3-Phenylpropionic acid (501-52-0) → trimethylsilyl ester of hydrocinnamic acid (21273-15-4)

Guidance literature:

With iodine; In neat (no solvent); at 20 ℃; for 6h; Green chemistry;

DOI:10.1016/j.tet.2016.08.003

Reference yield:

trimethylsilyl tert-butyl persuccinate → tert-butylperoxytrimethylsilane (3965-63-7) + Hexamethyldisiloxane (107-46-0) + trimethylsilyl propionate (16844-98-7) + trimethylsilyl ester of hydrocinnamic acid (21273-15-4) + acetone (67-64-1) + tert-butyl alcohol (75-65-0)

Guidance literature:

at 110 - 115 ℃; for 25h; Product distribution; Rate constant; Thermodynamic data; thermolysis without a solvent and with solvents;

DOI:10.1007/BF00963704

Reference yield:

trimethylsilyl 2-methylprop-2-ene-1-sulfinate (723336-86-5) + 3-Phenylpropionic acid (501-52-0) → trimethylsilyl ester of hydrocinnamic acid (21273-15-4)

Guidance literature:

In acetonitrile; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1021/ol401053y

upstream raw materials:

chloro-trimethyl-silane

3-Phenylpropionic acid

3-(trimethylsilyl)-2-oxazolidinone

trimethylsilyl 2-methylprop-2-ene-1-sulfinate

Downstream raw materials:

Trimethyl-((Z)-1-phenethyl-hex-1-enyloxy)-silane

Trimethyl-((Z)-1-phenethyl-hex-1-enyloxy)-silane

3-phenylpropionic acid 4-chlorophenyl ester

3-phenylthiopropionic acid S-4-chlorophenyl ester