Succinaldehyde

Base Information

• Chemical Name: Succinaldehyde
• CAS No.: 638-37-9
• Molecular Formula: C4H6O2
• Molecular Weight: 86.0904
• Hs Code.: 2912190090
• European Community (EC) Number: 211-333-8
• NSC Number: 11057
• UNII: 0503177591
• DSSTox Substance ID: DTXSID3021514
• Nikkaji Number: J6.923J
• Wikipedia: Succinaldehyde
• Wikidata: Q4864618
• Mol file: 638-37-9.mol

Synonyms:1,4-butane dialdehyde;butanedial;succindialdehyde

Chemical Property of Succinaldehyde

Chemical Property:

• Vapor Pressure: 3.22mmHg at 25°C
• Refractive Index: 1.386
• Boiling Point: 154.1 °C at 760 mmHg
• Flash Point: 50.4 °C
• PSA: 34.14000
• Density: 0.965 g/cm³
• LogP: 0.16440
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 86.036779430
• Heavy Atom Count: 6
• Complexity: 41.5

Purity/Quality:

98%,99%, ^*data from raw suppliers

SUCCINALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 40
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC=O)C=O

Technology Process of Succinaldehyde

There total 74 articles about Succinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclo-octa-1,5-diene (5259-72-3,10060-40-9,111-78-4) → butanedial (638-37-9)

Guidance literature:

cyclo-octa-1,5-diene; With ozone; In ethanol; dichloromethane; at -78 ℃;

With triphenylphosphine; In ethanol; dichloromethane; at -78 - 20 ℃;

DOI:10.3987/COM-07-S(U)56

Reference yield: 90.0%

cyclohexane (110-82-7,25012-93-5) + percarbonate de O,O-t-butyle et O-vinyle (85684-59-9) → 3-oxobutyraldehyde (625-34-3) + butanedial (638-37-9) + cyclohexylcyclohexane (92-51-3) + cyclohexylacetaldehyde (5664-21-1) + acetone (67-64-1) + tert-butyl alcohol (75-65-0)

Guidance literature:

at 140 ℃; for 3.5h; Product distribution; Mechanism; sealed tube;

Reference yield: 88.6%

Butane-1,4-diol (110-63-4) → butanedial (638-37-9)

Guidance literature:

With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In dichloromethane; water; at 0 - 10 ℃; for 1h;

upstream raw materials:

tetrahydrofuran

2,5-diethoxytetrahydrofurane

1,4-butenediol

succinaldehyde dioxime

Downstream raw materials:

tropinone

2-[1-methyl-5-(2-oxopropyl)pyrrolidin-2-yl]acetone

methyl 8-methyl-3-oxo-8-azabicyclo<3.2.1>octan-2-carboxylate

8-(2,3-dimethoxy-benzyl)-nortropan-3-one

Refernces

• 1、 Li, Chao,Xu, Xiao-Yong,Li, Ju-Ying,Ye, Qing-Fu,Li, Zhong. "Radiosynthesis of tritium-labeled novel nitromethylene neonicotinoids compounds with NaB3H4". . p. 256 - 259. Retrieved 2011.
• 2、 Hoye, Thomas R.,Jenkins, Scott A.. "Asymmetric Synthesis of Achiral Molecules: Meso Selectivity". . p. 6196 - 6198. Retrieved 1987.
• 3、 Armstrong, Alan,Pyrkotis, Constantina. "Synthetic studies on amphidinolides C and F: synthesis of the C18-C29 segment of amphidinolide F". . p. 3325 - 3328. Retrieved 2009.
• 4、 Xu, Renbo,Luo, Ming,Xia, Rui,Meng, Xiaoqing,Xu, Xiaoyong,Xu, Zhiping,Cheng, Jiagao,Shao, Xusheng,Li, Houju,Li, Zhong. "Seven-membered azabridged neonicotinoids: Synthesis, crystal structure, insecticidal assay, and molecular docking studies". . p. 11070 - 11079. Retrieved 2014.
• 5、 Gehrmann, Robin,Hertlein, Tobias,Hilgeroth, Andreas,Hopke, Elisa,Lalk, Michael,Ohlsen, Knut. "Novel small-molecule hybrid-antibacterial agents against s. Aureus and mrsa strains". . . Retrieved 2021/12/29.
• 6、 Cao, Xiaofeng,Chen, Xi,Chen, Yuce,Li, Zhong,Xu, Xiaoyong. "The structure modification of seven-membered aza-brigded neonicotinoids in order to investigate their impact on honey bees". . p. 835 - 844. Retrieved 2021/05/29.