1-PHENYL-2-PROPANOL

Base Information

• Chemical Name: 1-PHENYL-2-PROPANOL
• CAS No.: 14898-87-4
• Molecular Formula: C₉H₁₂O
• Molecular Weight: 136.194
• Hs Code.: 29062900
• Mol file: 14898-87-4.mol

Synonyms:Benzeneethanol, alpha-methyl-, (±PHENYLISOPROPYL ALCOHOL;BENZYLMETHYLCARBINOL;AURORA KA-7019;METHYLBENZYLCARBINOL;(+/-)-1-PHENYL-2-PROPANOL;1-PHENYL-2-PROPANOL;1-PHENYLPROPAN-2-OL

Chemical Property of 1-PHENYL-2-PROPANOL

Chemical Property:

• Appearance/Colour: Clear colorless liquid
• Vapor Pressure: 0.067mmHg at 25°C
• Refractive Index: n20/D 1.522(lit.)
• Boiling Point: 219-221 °C(lit.)
• Flash Point: 185 °F
• PSA: 20.23000
• Density: 0.973 g/mL at 25 °C(lit.)
• LogP: 1.60990

Purity/Quality:

98% ^*data from raw suppliers

1-Phenyl-2-propanol 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-PHENYL-2-PROPANOL

There total 362 articles about 1-PHENYL-2-PROPANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-phenylpropylene oxide (23355-97-7) → 3-phenyl-2-propanol (698-87-3,14898-87-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 2h; under 760.051 Torr; regioselective reaction;

DOI:10.1002/ejoc.200800992

Reference yield: 70.0%

1,2-epoxy-3-phenylpropane (4436-24-2) → 3-Phenyl-1-propanol (122-97-4) + 3-phenyl-2-propanol (698-87-3,14898-87-4)

Guidance literature:

With hydrogen; Pd⁰-EnCat^TM; In methanol; at 23 ℃; for 19h; under 30002.4 Torr;

DOI:10.1021/ol0358509

Reference yield: 69.0%

methylamine hydrochloride (593-51-1) + 1-phenyl-acetone (103-79-7,136675-26-8) → methamphetamin (7632-10-2) + 2,6-dimethyl-3,5-diphenylpyridine (65907-81-5) + 3-phenyl-2-propanol (698-87-3,14898-87-4) + N-benzoylmethamphetamine (73355-87-0) + N-(1-methyl-2-phenylethyl)benzamide (70631-05-9,1795-95-5) + N-acetylmethamphetamine (27765-80-6) + N-formylmethamphetamine (42932-20-7,26343-75-9,894793-16-9) + N-(β-phenylisopropyl)benzyl(methyl)ketimine (74917-80-9) + 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2) + 3,4-diphenylbut-3-en-2-one (1722-69-6)

Guidance literature:

With aluminum amalgam; sodium hydroxide; In methanol; at -10 - 60 ℃; for 1.5h;

DOI:10.1021/ac9005588

upstream raw materials:

2-hydroxy-1-phenylpropylamine

methyl magnesium iodide

2-iodo-1-phenylethan-1-ol

2-iodo-2-phenylethanol

Downstream raw materials:

(S)-Fluoro-phenyl-acetic acid (R)-1-methyl-2-phenyl-ethyl ester

(S)-Fluoro-phenyl-acetic acid (S)-1-methyl-2-phenyl-ethyl ester

1-phenyl-2-propyl nitrite

(1-methoxypropyl)benzene

Refernces

• 1、 Song, Heng,Ye, Ke,Geng, Peiyu,Han, Xiao,Liao, Rongzhen,Tung, Chen-Ho,Wang, Wenguang. "Activation of Epoxides by a Cooperative Iron-Thiolate Catalyst: Intermediacy of Ferrous Alkoxides in Catalytic Hydroboration". . p. 7709 - 7717. Retrieved 2017.
• 2、 Zhu, Yongzhong,Chuah, Gaikhuan,Jaenicke, Stephan. "Chemo- and regioselective Meerwein-Ponndorf-Verley and Oppenauer reactions catalyzed by Al-free Zr-zeolite beta". . p. 1 - 10. Retrieved 2004.
• 3、 Brunner, Henri,Fisch,Heinrich. "Asymmetric Catalyses, XXXIX: Monohydrosilanes in the Enantioselective Catalytical Hydrosilylation of Prochiral Ketones". . p. 525 - 532. Retrieved 1988.
• 4、 Kooti,Nasiri. "Synthesis of a novel magnetic nanocatalyst based on rhodium complex for transfer hydrogenation of ketone". . . Retrieved 2019.
• 5、 De Vries, Johannes G.,Gandini, Tommaso,Gennari, Cesare,Jiao, Haijun,Pignataro, Luca,Stadler, Bernhard M.,Tadiello, Laura,Tin, Sergey. "Regiodivergent Reductive Opening of Epoxides by Catalytic Hydrogenation Promoted by a (Cyclopentadienone)iron Complex". . p. 235 - 246. Retrieved 2022/01/03.
• 6、 Corti, Marco,Chiara, Rossella,Romani, Lidia,Mannucci, Barbara,Malavasi, Lorenzo,Quadrelli, Paolo. "g-C3N4/metal halide perovskite composites as photocatalysts for singlet oxygen generation processes for the preparation of various oxidized synthons". . p. 2292 - 2298. Retrieved 2021/04/12.