1722-69-6

Usage

Uses

Used in Pharmaceutical Industry:
(3Z)-3,4-diphenylbut-3-en-2-one is used as a starting material for the synthesis of various pharmaceuticals and organic compounds due to its versatile nature and potential biological activities.
Used in Medicine:
(3Z)-3,4-diphenylbut-3-en-2-one is used as a therapeutic agent for its anti-inflammatory, antioxidant, and anti-cancer properties, and has been studied for its potential applications in treating various diseases and conditions.
Used in Agriculture:
(3Z)-3,4-diphenylbut-3-en-2-one is used in agriculture for its potential applications in enhancing crop yield and improving plant resistance to diseases and pests.
Used in Material Science:
(3Z)-3,4-diphenylbut-3-en-2-one is used in material science for its potential applications in the development of new materials with unique properties and functions.

Upstream product

• 327077-79-2 4-chloro-3,4-diphenyl-butan-2-one 
• 27962-13-6 C₁₈H₁₈OS 
• 100-52-7 benzaldehyde 
• 103-79-7 1-phenyl-acetone 
• 7647-01-0 hydrogenchloride 
• 123-39-7 N-Methylformamide 
• 593-51-1 methylamine hydrochloride 
• 165335-53-5 1,2-diphenyl-2,3-butadien-1-ol 
• 650605-38-2 4,5-diphenyl-3-oxo-4-pentenoic acid ethyl ester 
• 15341-31-8 α-nitro-stilbene 
• 501-65-5 diphenyl acetylene 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 32644-22-7 1-methyl-3-phenylallene 
• 98-80-6 phenylboronic acid 

Downstream Products

• 94897-34-4 3,4-diphenyl-2-butanone 
• 74460-37-0 4-(1H-Benzoimidazol-2-ylmethylsulfanyl)-3,4-diphenyl-butan-2-one 
• 127056-94-4 (E)-5-Morpholin-4-yl-1,2-diphenyl-pent-1-en-3-one; hydrochloride 
• 70320-41-1 3-Phenylseleno-3,4-diphenyl-6-methyl-5-hepten-2-on 
• 67-66-3 chloroform 
• 91-48-5 (E)-2,3-diphenylpropenoic acid 
• 66221-08-7 1,2-diphenyl-6-methyltricyclo<2,2,0,0^2,6>hexane 
• 62907-52-2 3-methyl-1,2-diphenylbicyclo<3,1,0>hex-2-ene 
• 73377-56-7 (E)-3-methyl-3-methoxy-1,2-diphenyl-1,5-hexadiene 
• 62907-57-7 (E)-4-methyl-6-methoxy-5,6-diphenyl-1,4-hexadiene 
• 62907-50-0 1,2-diphenyl-3-allyl-3-methylcyclopropene 
• 73377-55-6 (Z)-4-methyl-6-methoxy-5,6-diphenyl-1,4-hexadiene 
• 131437-38-2 (Z)-3,4-diphenylbut-3-en-2-ol 

Relevant academic research and scientific papers

A stereoselective synthetic route to (Z)-α-organostannyl-α,β-unsaturated carbonyl compounds

Hydrozirconation of acetylenic stannanes 1 affords gemstannazirconocene alkenes 2. Intermediates 2 are treated with acyl halides to obtain (Z)-α-organostannyl-α,β-unsaturated carbonyl compounds 3 via Zr-Cu transmetallation.

Selective Cross-Dehydrogenative C(sp3)-H Arylation with Arenes

Selective C(sp3)-C(sp2) bond construction is of central interest in chemical synthesis. Despite the success of classic cross-coupling reactions, the cross-dehydrogenative coupling between inert C(sp3)-H and C(sp2)-H bonds represents an attractive alternative toward new C(sp3)-C(sp2) bonds. Herein, we establish a selective inter-and intramolecular C(sp3)-H arylation of alcohols with nondirected arenes that thereby provides a general pathway to access a wide range of β-arylated alcohols, including tetrahydronaphthalen-2-ols and benzopyran-3-ols, with high to excellent chemo-and regioselectivity.

Stereospecific Decarboxylative Nazarov Cyclization Mediated by Carbon Dioxide for the Preparation of Highly Substituted 2-Cyclopentenones

Highly substituted 2-cyclopentenones were stereospecifically and regioselectively constructed with high catalytic efficiency through Lewis-acid catalyzed decarboxylative Nazarov cyclization of the cyclic carbonate derivative, which is prepared by reacting the propargyl alcohol with carbon dioxide in the presence of a silver catalyst. The stereochemistry of the 2-cyclopentenone is strictly controlled by the geometry of the alkene in the starting material. This method is applicable for various substrates.

Enantioselective synthesis of β-substituted chiral allylic amines: Via Rh-catalyzed asymmetric hydrogenation

An asymmetric mono-hydrogenation of 2-acetamido-1,3-dienes catalyzed by a Rh-DuanPhos complex has been developed. This approach provides easy access to chiral allylic amines with excellent enantioselectivities and high regioselectivities. The products are valuable chiral building blocks for pharmaceuticals.

Preparation of 1-methyl-3-phenylisoquinoline derivatives from oximes using polyphosphoric esters

We show a beneficial new approach to the preparation of 1-methyl-3-phenylisoquinoline derivatives. This method involves heating polyphosphate ester and the appropriate oximes obtained from 3,4-diphenylbut-3-en-2-one derivatives. The isoquinolines were syn

Acid-catalyzed synthesis of α,β-disubstituted conjugated enones by a Meyer-Schuster-type rearrangement in allenols

A novel, direct and simple methodology to gain access to α,β-disubstituted conjugated enones from α-allenols in a sustainable metal catalysis context, considering the inexpensiveness and environmentally friendliness of iron(III) species and protons, has b

Copper-catalyzed regio- and stereoselective intermolecular three-component oxyarylation of allenes

A copper(II)-catalyzed intermolecular three-component oxyarylation of allenes using arylboronic acids as a carbon source and TEMPO as an oxygen source is described. The reaction proceeded under mild conditions with high regio- and stereoselectivity and functional group tolerance. A plausible reaction mechanism is proposed, involving carbocupration of allenes, homolysis of the intervening allylcopper(II), and a radical TEMPO trap.

Synthesis and antimicrobial evaluation of some pyrazole derivatives

Reaction of a series of (E)-3-phenyl-4-(p-substituted phenyl)-3-buten-2- ones with p-sulfamylphenyl hydrazine in glacial acetic acid gave the corresponding hydrazones, subsequent treatment of which with 30% HCl afforded pyrazole-1-sulphonamides. On the ot

Iridium-catalyzed asymmetric hydrogenation of α-substituted α,β-unsaturated acyclic ketones: Enantioselective total synthesis of (-)-mesembrine

A highly efficient asymmetric hydrogenation of α-substituted α,β-unsaturated acyclic ketones catalyzed by chiral spiro iridium complexes for the preparation of chiral 2-substituted allylic alcohols has been developed (ee up to 99.7%). This method provides a concise route to (-)-mesembrine (34% yield, 12 steps).

H2SO4-promoted synthesis of (E)-stilbenes from substituted phenylacetones and substituted benzaldehydes through tandem aldol-Grob reaction

Stilbene derivates (stilbenoids) are present in plants and show a wide range of biological activities and potential therapeutic value. In continuation of our natural product synthesis program, an efficient, simple, and practical method has been developed to regioselectively synthesize (E)-stilbenes using H2SO4 as a catalyst in a short time (30-60 s) at room temperature in good to excellent yields.