4-Bromo-2,6-difluoroanisole

Base Information

Chemical Name:4-Bromo-2,6-difluoroanisole
CAS No.:104197-14-0
Molecular Formula:C7H5BrF2O
Molecular Weight:223.017
Hs Code.:2909309090
European Community (EC) Number:642-791-0
DSSTox Substance ID:DTXSID20378339
Nikkaji Number:J1.302.328J
Wikidata:Q72454276
Mol file:104197-14-0.mol

Synonyms:4-Bromo-2,6-difluoroanisole;104197-14-0;5-Bromo-1,3-difluoro-2-methoxybenzene;5-bromo-1,3-difluoro-2-methoxy-benzene;Benzene, 5-bromo-1,3-difluoro-2-methoxy-;4-bromo-2,6-difluorophenyl methyl ether;4-bromo-2,6-difluoranisole;SCHEMBL10986;4-bromo-2,6-difluoro-anisol;DTXSID20378339;CDOQKISJPOWBKC-UHFFFAOYSA-N;3,5-difluoro-4-methoxy-bromobenzene;MFCD01631351;AKOS015835523;CS-W013104;1-Bromo-3,5-difluoro-4-methoxybenzene;PS-10172;AM20020135;B3391;FT-0642560;EN300-6776529

Suppliers and Price of 4-Bromo-2,6-difluoroanisole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-2,6-difluoroanisole
100mg
$ 75.00

TCI Chemical
4-Bromo-2,6-difluoroanisole >98.0%(GC)
5g
$ 165.00

SynQuest Laboratories
4-Bromo-2,6-difluoroanisole 98%
5 g
$ 98.00

Matrix Scientific
4-Bromo-2,6-difluoroanisole 97%
5g
$ 69.00

Matrix Scientific
4-Bromo-2,6-difluoroanisole 97%
1g
$ 19.00

Crysdot
5-Bromo-1,3-difluoro-2-methoxybenzene 97%
25g
$ 185.00

Crysdot
5-Bromo-1,3-difluoro-2-methoxybenzene 97%
10g
$ 102.00

Crysdot
5-Bromo-1,3-difluoro-2-methoxybenzene 97%
5g
$ 61.00

Apolloscientific
4-Bromo-2,6-difluoroanisole 98%
5g
$ 83.00

AOBChem
5-Bromo-1,3-difluoro-2-methoxybenzene 97%
5g
$ 58.00

Total 69 raw suppliers

Chemical Property of 4-Bromo-2,6-difluoroanisole

Chemical Property:

Appearance/Colour:clear, colorless liquid
Vapor Pressure:0.469mmHg at 25°C
Refractive Index:1.575
Boiling Point:214.2 °C at 760 mmHg
Flash Point:98.5 °C
PSA：9.23000
Density:1.615 g/cm³
LogP:2.73590
Storage Temp.:Store Cold
Sensitive.:Light Sensitive
Water Solubility.:Insoluble in water.
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:221.94918
Heavy Atom Count:11
Complexity:122

Purity/Quality:

98% ^*data from raw suppliers

4-Bromo-2,6-difluoroanisole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, F
Hazard Codes:Xi,F
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1F)Br)F
Uses t is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Technology Process of 4-Bromo-2,6-difluoroanisole

There total 5 articles about 4-Bromo-2,6-difluoroanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 67-56-1
methanol

: 138526-69-9
3,4,5-trifluoro-1-bromobenzene

: 104197-14-0
5-bromo-1,3-difluoro-2-methoxy-benzene

Guidance literature:: With lithium hydroxide; In dimethyl sulfoxide; at 100 ℃; for 24h;

Reference yield: 68.0%

: 104197-13-9
4-bromo-2,6-difluorophenol

: 74-88-4
methyl iodide

: 104197-14-0
5-bromo-1,3-difluoro-2-methoxy-benzene

Guidance literature:: With potassium carbonate; In acetone; at 0 - 20 ℃; for 22h;

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 2357-52-0
3-fluoro-4-methoxyphenyl bromide

: 104197-14-0
5-bromo-1,3-difluoro-2-methoxy-benzene

Guidance literature:: With formic acid; fluorine; at 10 ℃; for 1.75h; Title compound not separated from byproducts;
DOI:10.1016/S0022-1139(99)00238-9