1-methoxy-N-methyl-N-nitrosoethanamine

Base Information

• Chemical Name: 1-methoxy-N-methyl-N-nitrosoethanamine
• CAS No.: 61738-05-4
• Molecular Formula: C4H10N2O2
• Molecular Weight: 118.136
• Mol file: 61738-05-4.mol

Synonyms:N-(1-Methoxyethyl)-N-nitrosomethylamin;1-Methoxy-aethyl-methylnitrosamin;1-methoxy-N-methyl-N-nitrosoethanamine;ETHYLAMINE,1-METHOXY-N-METHYL-N-NITROSO;1-Methoxy-ethyl-methylnitrosamine;1-Methoxy-aethyl-methylnitrosamin [German];methyl(1-methoxyethyl)nitrosamine;N-Nitroso-N-methyl-1-methoxyethylamine;

Chemical Property of 1-methoxy-N-methyl-N-nitrosoethanamine

Chemical Property:

• Vapor Pressure: 0.805mmHg at 25°C
• Refractive Index: 1.4386 (estimate)
• Boiling Point: 189°C at 760 mmHg
• Flash Point: 68.1°C
• PSA: 41.90000
• Density: 1.04g/cm³
• LogP: 0.59200

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-methoxy-N-methyl-N-nitrosoethanamine

There total 3 articles about 1-methoxy-N-methyl-N-nitrosoethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + methylvinylnitrosamine (4549-40-0) → N-Nitroso-N-methyl-1-methoxyethylamine (61738-05-4)

Guidance literature:

hydrogenchloride; In diethyl ether; at 0 ℃;

DOI:10.1021/jo01302a037

Reference yield: 33.0%

methanol (67-56-1) + acetaldehyde (75-07-0,9002-91-9) + methylamine (74-89-5) → N-Nitroso-N-methyl-1-methoxyethylamine (61738-05-4)

Guidance literature:

With sodium nitrite; In water; acetic acid; at 4 ℃;

DOI:10.1021/jo00162a019

Reference yield:

N-ethylidenemethylamine (6898-67-5) + sodium methylate (124-41-4) → N-Nitroso-N-methyl-1-methoxyethylamine (61738-05-4)

Guidance literature:

With nitrosylchloride; Yield given. Multistep reaction; 1.) CH₂Cl₂, 1 h, -30 deg C; 2 h, 0 deg C, 2.) 12 h;

upstream raw materials:

methanol

methylvinylnitrosamine

N-ethylidenemethylamine

sodium methylate

Downstream raw materials:

N-Nitroso-N-(phenylethyl)-1-methoxyethylamine

N-methyl-ethylamine hydrochloride

N-Nitroso-N-ethyl-1-methoxyethylamine