Calcium

Base Information

• Chemical Name: Calcium
• CAS No.: 7440-70-2
• Deprecated CAS: 8047-59-4
• Molecular Formula: Ca
• Molecular Weight: 42.0939
• Hs Code.: 28051200
• European Community (EC) Number: 231-179-5
• ICSC Number: 1192
• UN Number: 1401,1855
• UNII: SY7Q814VUP
• DSSTox Substance ID: DTXSID9050484
• Wikipedia: Calcium
• Wikidata: Q706
• NCI Thesaurus Code: C331
• RXCUI: 1895
• ChEMBL ID: CHEMBL2146121
• Mol file: 7440-70-2.mol

Synonyms:Blood Coagulation Factor IV;Calcium;Calcium 40;Calcium-40;Coagulation Factor IV;Factor IV;Factor IV, Coagulation

Chemical Property of Calcium

Chemical Property:

• Appearance/Colour: softish silver-white metal
• Melting Point: 850 °C(lit.)
• Boiling Point: 1484 °C(lit.)
• PSA: 0.00000
• Density: 1.54 g/mL
• LogP: 0.22500
• Storage Temp.: water-free area
• Sensitive.: air sensitive, moisture sensitiv
• Water Solubility.: reacts with H2O, alcohols, dilute acids to evolve H2 [MER06]
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 39.9625908
• Heavy Atom Count: 1
• Complexity: 0
• Transport DOT Label: Dangerous When Wet,Spontaneously Combustible

Purity/Quality:

99.9% ^*data from raw suppliers

Calcium ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 15
• Safety Statements: 8-24/25-43

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Elements, Metallic
• Canonical SMILES: [Ca]
• Recent ClinicalTrials: The Effect of Calcium Intake on Calcium and Bone Metabolism During Load Carriage in Women
• Recent EU Clinical Trials: Phase III Randomized Double-blind Cross-over trial of Supersaturated Calcium-phosphate rinse (Caphosol?) versus NaCl 0.9% in the relief of Oral Mucositis in renal cell carcinoma, hepatocellular carcinoma, and gastrointestinal stromal tumor patients receiving Targeted Therapy
• Recent NIPH Clinical Trials: Effects of new dialysate for Japanese dialysis patients (K5) on serum electrolytes, acid-base balance, and calcium mass balance: A prospective multicenter clinical trial.
• Inhalation Risk: A harmful concentration of airborne particles can be reached quickly when dispersed.
• Effects of Short Term Exposure: The substance is corrosive to the eyes, skin and respiratory tract.
• Effects of Long Term Exposure: Repeated or prolonged contact with skin may cause dermatitis.
• Physical properties: Bright, silvery-white metal; face-centered cubic crystal structure (α = 0.5582 nm) at ordinary temperatures, transforming to body-centered cubic form (α = 0.4407) at 430°C; density 1.54 g/cm3 at 20°C; hardness 2 Mohs, 17 Brinnel (500 kg load); melts at 851°C; vaporizes at 1,482°C; electrical resistivity 3.43 and 4.60 microhm-cm at 0° and 20°C, respectively; modulus of elasticity 3-4x106 psi; mass magnetic susceptibility +1.10x10-6 cgs; surface tension 255 dynes/cm; brick-red color when introduced to flame (flame test); standard reduction potential E° = -2.87V.
• Uses: Calcium is largely used in the production of steel however it may also be applied to various health treatments involving the calcium-channel and anti-depressant activity. In addition it may be a necessary supplement in fracture healing of bones in mammals. Calcium is used as a deoxidizer for copper,steel, and beryllium in metallurgy; to hardenlead for bearing; and in making alloys. Reducing agent for production of less common metals; alloying agent to increase strength and corrosion resistance in lead, to improve mechanical and electrical properties in aluminum; refining agent to remove bismuth from lead. In metallurgy as scavenger to deoxidize, desulfurize and degas steel and cast iron; to control non-metallic inclusions in steel; to promote uniform microstructure in gray iron. As anode material in thermal batteries; as "getter" for oxygen and nitrogen.

Technology Process of Calcium

There total 110 articles about Calcium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

calcium carbide (75-20-7) → graphite + calcium (7440-70-2)

Guidance literature:

In neat (no solvent); pressure about 1 Torr, 1600-1800°C; small amts. of Ca;;

Reference yield:

aluminium (7429-90-5) + calcium carbonate → aluminum oxide (1333-84-2,1344-28-1) + calcium (7440-70-2)

Guidance literature:

In neat (no solvent); byproducts: C; heating equal amounts of carbonate and Al powder at red heat;; powdery product mixture obtained;;

Reference yield:

selenium oxychloride (7791-23-3) → disulfur dichloride (10025-67-9) + calcium (7440-70-2)

Guidance literature:

With sulfur; byproducts: SO2; heating; no reaction in cold SeOCl2;;

DOI:10.1021/ja01434a005

upstream raw materials:

sulfuric acid

aluminum oxide

calcium chloride

calcium azide

Downstream raw materials:

sumatripan

chromium

sodium

silver

Refernces

Synthesis and ¹H NMR titration study of 7-deoxycholic amide or cholane ionophores containing different ion-recognizing groups at C3 and C12

10.1002/hc.21002

The research focuses on the synthesis and 1H NMR titration study of 7-deoxycholic amide or cholane ionophores containing different ion-recognizing groups at C3 and C12. The purpose of this study is to develop new types of ionophores based on a deoxycholic acid backbone (DCAB) that can selectively recognize calcium ions. The researchers synthesized ionophores with a carbamoylpropanamidoacetoxy group at the C3 position and a dithiocarbamoyl group at the C12 position. Key chemicals used in the synthesis include deoxycholic acid, α-chloroacetyl chloride, sodium azide, nanosized zinc powder, and various N,N-di(alkyl, aryl)carbamoylpropanoic acids. The 1H NMR titration experiments showed that the synthesized ionophores form 1:1 complexes with the Ca2+ ion, indicating that the oxygen atoms in the dithiocarbamoyl and carbamoylpropanamidoacetoxy moieties are largely responsible for calcium ion recognition. The conclusion is that these uniquely designed ionophores exhibit high selectivity for calcium ions, which could be useful in the development of ion-selective electrodes and other chemical sensors.