diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

• Chemical Name: diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• CAS No.: 83300-83-8
• Molecular Formula: C₂₅H₂₇NO₆
• Molecular Weight: 437.492
• Mol file: 83300-83-8.mol

Synonyms:diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property of diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

There total 1 articles about diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

4-methoxy-benzaldehyde (123-11-5) + 4-methoxy-aniline (104-94-9) + propynoic acid ethyl ester (623-47-2) → diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate (83300-83-8)

Guidance literature:

With acetic acid; In ethanol; at 80 ℃;

DOI:10.3390/molecules24162873

Reference yield: 49.0%

diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate (83300-83-8) → 1,4-Bis-(4-methoxy-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid monoethyl ester (83300-89-4)

Guidance literature:

With potassium hydroxide; In ethanol; for 10h; Heating;

DOI:10.1007/BF00506586

Reference yield:

methanol (67-56-1) + diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate (83300-83-8) → MC2737 (83300-95-2) + dimethyl 1,4-diphenyl-1,4-dihydropyridine-3,5-dicarboxylate (83300-84-9)

Guidance literature:

With potassium hydroxide;

DOI:10.1007/BF00506586

upstream raw materials:

4-methoxy-benzaldehyde

4-methoxy-aniline

propynoic acid ethyl ester

Downstream raw materials:

MC₂₇₃₇

dimethyl 1,4-diphenyl-1,4-dihydropyridine-3,5-dicarboxylate

1,4-Bis-(4-methoxy-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid monoethyl ester