Formaldehyde

Base Information

• Chemical Name: Formaldehyde
• CAS No.: 35907-63-2
• Deprecated CAS: 112068-71-0,8005-38-7,8006-07-3,8013-13-6,1053659-79-2,1156543-56-4,1158237-02-5,1227476-28-9,1357848-44-2,1416946-65-0,1609158-91-9,1196157-74-0,2100305-91-5,1053659-79-2,1156543-56-4,1158237-02-5,1227476-28-9,8005-38-7,8006-07-3,8013-13-6
• Molecular Formula: CO
• Molecular Weight: 31
• European Community (EC) Number: 200-001-8,685-227-9
• ICSC Number: 0275
• NSC Number: 298885
• UN Number: 3077,1198,2209
• UNII: 1HG84L3525
• DSSTox Substance ID: DTXSID7020637
• Nikkaji Number: J2.294B,J369.708H
• Wikipedia: Formaldehyde
• Wikidata: Q161210,Q27110014
• NCI Thesaurus Code: C29744
• RXCUI: 4530
• Pharos Ligand ID: GLZFC5QP99RT
• Metabolomics Workbench ID: 50670
• ChEMBL ID: CHEMBL1255
• Mol file: 35907-63-2.mol

Synonyms:Formaldehyde;Formalin;Formol;Methanal;Oxomethane

Chemical Property of Formaldehyde

Chemical Property:

• Melting Point: -205 °C(lit.)
• Boiling Point: -191.5 °C(lit.)
• PSA: 17.07000
• LogP: 0.45100
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 30.010564683
• Heavy Atom Count: 2
• Complexity: 2
• Transport DOT Label: Class 9

Purity/Quality:

95% ^*data from raw suppliers

Carbon-13C monoxide-18O Gas 99 atom % 13C, 95 atom % 18O ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F+,T
• Statements: 61-12-23-48/23
• Safety Statements: 53-45

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Aldehydes
• Canonical SMILES: C=O
• Recent NIPH Clinical Trials: Assessment of Evaluation of tumor cell content ratio using endocytoscopy in biopsy tissue.
• Inhalation Risk: A harmful concentration of this gas in the air will be reached very quickly on loss of containment.
• Effects of Short Term Exposure: The substance is severely irritating to the eyes and respiratory tract. Inhalation of high concentrations may cause lung oedema, but only after initial corrosive effects on the eyes and the upper respiratory tract have become manifest.
• Effects of Long Term Exposure: Repeated or chronic inhalation of the vapour may cause chronic inflammation of the upper respiratory tract. Repeated or prolonged contact may cause skin sensitization. This substance is carcinogenic to humans.

Technology Process of Formaldehyde

There total 2 articles about Formaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol-1-13C (14742-23-5) → carbon monoxide-13C-18O (35907-63-2) + carbon dioxide-13C-18O1 (20201-82-5) + methane (6532-48-5) + ethane-13C1 (6145-17-1) + methane (34557-54-5,27936-85-2) + ethane (74-84-0) + ethene (74-85-1) + ethane-13C2 (52026-74-1) + [13C2]ethene (51915-19-6) + mono-[13C]-ethylene (6145-18-2) + carbon dioxide (124-38-9,18923-20-1) + carbon monoxide (55125-78-5) + carbon dioxide (1111-72-4) + [13C]Carbon monoxide (1641-69-6) + carbon dioxide (2537-69-1) + CO(18)O (18983-82-9) + carbon dioxide (2684-00-6)

Guidance literature:

With ¹⁸O-labeled water; at 350 ℃; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/anie.201604388

Reference yield:

ethanol-1-13C (14742-23-5) → carbon monoxide-13C-18O (35907-63-2) + carbon dioxide-13C-18O1 (20201-82-5) + methane (6532-48-5) + ethane-13C1 (6145-17-1) + methane (34557-54-5,27936-85-2) + ethane (74-84-0) + ethene (74-85-1) + ethane-13C2 (52026-74-1) + [13C2]ethene (51915-19-6) + mono-[13C]-ethylene (6145-18-2) + carbon monoxide (55125-78-5) + carbon dioxide (1111-72-4) + [13C]Carbon monoxide (1641-69-6) + carbon dioxide (2537-69-1) + CO(18)O (18983-82-9) + carbon dioxide (2684-00-6)

Guidance literature:

With ¹⁸O-labeled water; at 350 ℃; Inert atmosphere;

DOI:10.1002/anie.201604388

Reference yield:

1,2-bis(diphenylphosphino)ethane nickel(II) chloride (14647-23-5) + carbon monoxide-13C-18O (35907-63-2) + [NEt4][Fe(N(CH2CH2S)3)(CO)] (220024-66-8) → [(Fe(N(CH2CH2S)3)(CO)2-S,S')NiCl(dppe)] (250275-84-4)

Guidance literature:

In acetonitrile; under (13)CO atm. to stirred suspn. (NiCl2(dppe)) in MeCN was added soln. (NEt4)(Fe(N(CH2CH2S)3)(CO)) in MeCN and stirred for 30 min;

upstream raw materials:

ethanol-1-13C

Downstream raw materials:

[(Fe(N(CH₂CH₂S)3)(CO)2-S,S')NiCl(dppe)]

Refernces