Propanethioic acid, S-(4-methoxyphenyl) ester

Base Information

• Chemical Name: Propanethioic acid, S-(4-methoxyphenyl) ester
• CAS No.: 120346-05-6
• Molecular Formula: C10H12O2S
• Molecular Weight: 196.27
• Mol file: 120346-05-6.mol

Synonyms:

Chemical Property of Propanethioic acid, S-(4-methoxyphenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanethioic acid, S-(4-methoxyphenyl) ester

There total 4 articles about Propanethioic acid, S-(4-methoxyphenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-Methoxybenzenethiol (696-63-9) + propionyl chloride (79-03-8) → S-(4-methoxyphenyl) propanethioate (120346-05-6)

Guidance literature:

With tetrabutyl-ammonium chloride; sodium hydroxide; In dichloromethane; water; at 0 ℃; for 0.0833333h;

DOI:10.1080/10426501003713072

Reference yield: 80.0%

4-Methoxybenzenethiol (696-63-9) + carbon monoxide (201230-82-2) + ethyl iodide (75-03-6) → S-(4-methoxyphenyl) propanethioate (120346-05-6)

Guidance literature:

With di-μ-chlorobis(norbornadiene)dirhodium(I); 1,3-bis-(diphenylphosphino)propane; caesium carbonate; sodium fluoride; In 1,4-dioxane; at 140 ℃; for 12h; under 4500.45 Torr; Sealed tube; Autoclave;

DOI:10.1039/d0cc07578g

Reference yield:

N-phenylpropanethioamide (2955-69-3) + 4-methoxybenzenediazonium tetrafluoroborate (459-64-3) → 4,4'-dimethoxyphenyl disulfide (5335-87-5) + N-(phenyl)-2-methylacetamide (620-71-3) + S-(4-methoxyphenyl) propanethioate (120346-05-6) + N-Phenyl-thiopropionimidic acid 4-methoxy-phenyl ester (120346-00-1)

Guidance literature:

With ferrocene; In acetone; at 20 ℃; for 3h; Further byproducts given. Yields of byproduct given;

DOI:10.1007/BF00962753

upstream raw materials:

N-phenylpropanethioamide

4-methoxybenzenediazonium tetrafluoroborate

4-Methoxybenzenethiol

propionyl chloride

Refernces

• 1、 Simion, Cristian,Hashimoto, Iwao,Mitoma, Yoshiharu,Simion, Alina Marieta,Egashira, Naoyoshi. "Rapid and convenient thioester synthesis under phase-transfer catalysis conditions". experimental part. p. 2480 - 2488. Retrieved 2011/02/23.
• 2、 Bragina, I. O.,Kandor, I. I.. "SYNTHESIS OF ISOTHIOAMIDES OF Alk-C(SAr)=NAr BY RADICAL ARYLATION OF THIOAMIDES". . p. 1411 - 1415. Retrieved 2007/10/02.