Work-up and Isolation

Synthesis Functionalization Regioselectivity Characterization Reagents Reaction scheme Nucleophilic addition Biologically active compounds {(5,7-dimethyl-6-oxo-4a,7a-diphenyl-4,4a,5,6,7,7a-hexahydro-1H-imidazo[4,5-e]-1,2,4-triazin-3-yl)thio}acetic acid 1,3-dimethyl-3a,9a-diphenyl-3,3a,9,9a-tetrahydroimidazo[4,5-e]-1,3-thiazolo[3,2-b]-1,2,4-triazine-2,7(1H,6H)-dione Anticancer agents Fungicides Bactericides Purification Materials and Reagents Work-Up Stereochemistry Control Preparation of 5,7-dimethyl-4a,7a-diphenyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-one Reaction with Halogenoacetic Acid Chiral Catalyst Substrate Design Copper catalyst Activation of Methylene C-H Bond Addition of Nitroarene Reduction of Nitro Group Sulfur Addition Preparation of Lithioalkenylcarboxamides Cyclization to Form the Ring Phenylacetic acid (Ar-CH2COOH) N,N-dialkylformamide (R2NCHO) Activation of Phenylacetic Acid Formation of Acyl Copper Intermediate Reaction with N,N-dialkylformamide Amino-Crotylation Imines Formation Reductive Conditions Hydrolysis of α-formyl-γ-lactone Conversion to an Acid Chloride Wittig Reaction Preparation of Indol-2-yl Carbinol Formation of Enamide Organocatalytic Asymmetric Addition Reaction Procedure Preparation of Sodium Arylsulfinates Pd-Catalyzed Reduction of Nitroarenes Coupling with Sodium Arylsulfinate Amination Reaction Activation of NHC Formation of the boron nucleophile Formation of a boronate intermediate