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102-06-7

Basic Information
CAS No.: 102-06-7
Name: 1,3-Difenylguanid
Molecular Structure:
Molecular Structure of 102-06-7 (1,3-Difenylguanid)
Formula: C13H13N3
Molecular Weight: 211.29
Synonyms: N,N Diphenyl guanidine;Chemicals & Rubber Accelerator DPG;Chemicals & Rubber Accelerator DPG (Dephenyl Guanidine);Accelerator DPG(D);Vulkacit D;N,N-Diphenylguanidine;Rhenogran DPG 80P;Perkacit DP;Chlorostain BR;Sanceler D;s-Diphenylguanidine;Melaniline;(amino-anilino-methylidene)-phenyl-azanium;1,2-diphenylguanidine;Accelerator D;Diphenylguanidine;Vulkazit;Guanidine, 1, 3-diphenyl-;Rubber Accelerator DPG (D);N-Oxydiethylene-2-Benzothiazole Sulfenamide (NOBS);Accelerator DPG (D);Accelerator DPG;Diphenyl guanidine;Accelerator D;Diphenyl guanidine;Rubber accelerator DPG;N,N′-diphenylguanidine;
EINECS: 203-002-1
Density: 1.1 g/cm3
Melting Point: 146-148 °C(lit.)
Boiling Point: 338.5 °C at 760 mmHg
Flash Point: 158.5 °C
Solubility: slightly soluble in water
Appearance: White to cream-colored chalky powder
Hazard Symbols: HarmfulXn,DangerousN
Risk Codes: 22-36/37/38-51/53-62
Safety: 26-36/37/39-61
Transport Information: UN 3077 9/PG 3
PSA: 47.91000
LogP: 3.39110
Synthetic route
102-08-9

N,N-diphenylthiourea

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With ammonium hydroxide; oxygen; copper diacetate In ethyl acetate; acetone at 60℃; under 1875.19 Torr; for 0.05h; Reagent/catalyst; Temperature; Pressure; Solvent;96.1%
With ammonia; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In water; acetonitrile at 20℃;90%
With lead; potassium hydroxide; ammonia; water dann mit verd.Salzsaeure;
591-50-4

iodobenzene

506-93-4

guanidine nitrate

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; sarcosine In acetonitrile at 70℃; for 8h; Ullmann reaction; Inert atmosphere;90%
With potassium phosphate; copper(l) iodide; N,N-diethylsalicylamide In acetonitrile at 80℃; Inert atmosphere;83%
108-86-1

bromobenzene

506-93-4

guanidine nitrate

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; sarcosine In acetonitrile at 90 - 100℃; for 20h; Ullmann reaction; Inert atmosphere;81%

(1,3-diphenyltetrazolium-5-yl)anilide

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With acetic acid; zinc In dichloromethane at 20℃; Reduction; ultrasonication;78%
591-50-4

iodobenzene

1-(4-methoxybenzyl)guanidine hemisulfate

A

102-06-7

diphenylguanidine

B

1241493-92-4

1-(4-methoxybenzyl)-3-phenylguanidine

Conditions
ConditionsYield
With potassium phosphate; copper(I) thiophene-2-carboxylate; D-Prolin In acetonitrile at 100℃; for 3h; Modified Ullmann reaction; Inert atmosphere;A 15%
B 71%
62-53-3

aniline

3674-54-2

tetrabutylammonium thiocyanate

102-06-7

diphenylguanidine

Conditions
ConditionsYield
Multistep reaction;47%
62-53-3

aniline

123564-74-9

N-phenyl-imidazole-1-carboxamidine

A

102-06-7

diphenylguanidine

B

1973-05-3

triphenyl melamine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 90℃; for 12h;A 15%
B n/a
20028-19-7

N-(N,N'-diphenylguanyl)-benzamidine

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With potassium carbonate
5067-80-1

N-benzoyl-N',N''-diphenyl-guanidine

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With potassium hydroxide
506-68-3

bromocyane

62-53-3

aniline

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With water at 80 - 85℃;
542-85-8

Ethyl isothiocyanate

62-53-3

aniline

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With mercury dichloride at 120℃;

S-(2-acetoxy-ethyl)-N-phenyl-isothiourea

62-53-3

aniline

102-06-7

diphenylguanidine

Conditions
ConditionsYield
at 150℃;
6522-91-4

N-phenyl-guanidine hydrochloride

62-53-3

aniline

102-06-7

diphenylguanidine

Conditions
ConditionsYield
at 150℃;
92114-96-0

mercury fulminate

62-53-3

aniline

A

102-06-7

diphenylguanidine

B

64-10-8

phenyl carbamate

Conditions
ConditionsYield
With ethanol
62-53-3

aniline

506-77-4

cyanogen chloride

102-06-7

diphenylguanidine

142-04-1

aniline hydrochloride

127099-85-8, 780722-26-1

N-Cyanoguanidine

102-06-7

diphenylguanidine

Conditions
ConditionsYield
at 190 - 200℃;
4484-20-2

aniline benzenesulfonate

127099-85-8, 780722-26-1

N-Cyanoguanidine

102-06-7

diphenylguanidine

Conditions
ConditionsYield
at 200℃;
613-92-3

N-hydroxybenzenecarboximidamide

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With pyridine; benzenesulfonyl chloride; benzene Erwaermen des Reaktionsgemisches mit Anilin;
142-04-1

aniline hydrochloride

102-02-3

1-phenylbiguanide

A

102-06-7

diphenylguanidine

B

113-00-8

guanidine nitrate

C

2002-16-6

1-phenylguanidine

Conditions
ConditionsYield
das Hydrochlorid reagiert;
142-04-1

aniline hydrochloride

622-34-4

1-phenylcyanamide

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With ethanol
135672-76-3

dipropyldithiophosphoric acid N,N'-diphenylguanidinium salt

A

18944-65-5

dithiophosphoric acid O,O',S-tripropyl ester

B

102-06-7

diphenylguanidine

C

135672-88-7

Dithiophosphoric acid O-propyl ester

D

2253-43-2

O.O-Dipropyl-dithyophosphat

Conditions
ConditionsYield
at 143℃; for 0.5h;
25343-52-6

N-Phenylaminoiminomethanesulfonic acid

62-53-3

aniline

102-06-7

diphenylguanidine

Conditions
ConditionsYield
In acetonitrile at 35℃; for 0.25h; Yield given;
62-53-3

aniline

103-85-5

monophenylthiourea

102-06-7

diphenylguanidine

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; chlorotriisopropylsilane; sodium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; trifluoroacetic acid 1.) THF; 3.) CH2Cl2; Yield given. Multistep reaction;
103-85-5

monophenylthiourea

p-amino-phenylmercury chloride

p-amino-phenylmercury chloride

102-06-7

diphenylguanidine

1071-37-0

2-ethylisothiourea hydrobromide

62-53-3

aniline

A

102-06-7

diphenylguanidine

B

phenylguanidine, guanidine

phenylguanidine, guanidine

Conditions
ConditionsYield
With water at 100℃;
With pyridine at 100℃;
854695-59-3

S-(4-dimethylamino-phenyl)-N,N'-diphenyl-isothiourea

7664-41-7

ammonia

A

4946-22-9

N,N-dimethyl-4-aminothiophenol

B

102-06-7

diphenylguanidine

Conditions
ConditionsYield
at 120℃;
14779-12-5

N,N''-diphenyl-μ-disulfido-dicarboxamidine; dihydrobromide

aqueous methanol.NaOH

aqueous methanol.NaOH

A

102-06-7

diphenylguanidine

B

622-34-4

1-phenylcyanamide

C

103-85-5

monophenylthiourea

D

sulfur

sulfur

103-85-5

monophenylthiourea

alcoholic iodine

alcoholic iodine

102-06-7

diphenylguanidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / NaCl, Na2MoO4*2H2O, 30percent H2O2 / H2O
2: acetonitrile / 0.25 h / 35 °C
View Scheme
20277-92-3

diphenylguanidine

102-06-7

diphenylguanidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: alcohol; lead oxide; ammonia
View Scheme
102-06-7

diphenylguanidine

59565-09-2

2-(vinyloxy)ethyl isothiocyanate

C18H20N4OS

Conditions
ConditionsYield
at 60℃; for 0.5h;100%
102-06-7

diphenylguanidine

2253-43-2

O.O-Dipropyl-dithyophosphat

135672-76-3

dipropyldithiophosphoric acid N,N'-diphenylguanidinium salt

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;98%
102-06-7

diphenylguanidine

27545-53-5

3-phenyl-isothiazole-4,5-dicarboxylic acid dimethyl ester

76240-12-5

methyl 5-<(NN'-diphenylamidino)carbamoyl>-3-phenylisothiazole-4-carboxylate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 6h; Heating;97%
50-00-0

formaldehyd

102-06-7

diphenylguanidine

103-84-4

Acetanilid

Conditions
ConditionsYield
With platinum(II) acetylacetonate; 1-carboxyethyl-3-methylimidazolium hydrogen bisulfate; zinc diacetate; copper(II) bis(trifluoromethanesulfonate) at 50℃; for 8h; Reagent/catalyst;96.8%
2253-52-3

O,O'-diisobutyldithiophosphoric acid

102-06-7

diphenylguanidine

135672-79-6

N,N'-Diphenyl-guanidine; compound with dithiophosphoric acid O,O'-diisobutyl ester

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;96%
102-06-7

diphenylguanidine

7595-89-3

dithiophosphoric acid O,O'-di-m-tolyl ester

135672-85-4

Dithiophosphoric acid O,O'-di-m-tolyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;96%
102-06-7

diphenylguanidine

756-80-9

O,O-dimethyl phosphorodithioic acid

135672-74-1

N,N'-Diphenyl-guanidine; compound with dithiophosphoric acid O,O'-dimethyl ester

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature; other diorganyldithiophosphoric acids;96%
In chloroform for 0.25h; Ambient temperature;96%
102-06-7

diphenylguanidine

107-56-2

O,O-diisopropyl hydrogen phosphorodithioate

135672-77-4

N,N'-Diphenyl-guanidine; compound with dithiophosphoric acid O,O'-diisopropyl ester

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;96%
102-06-7

diphenylguanidine

298-06-6

O,O-Diethyl hydrogen phosphorodithioate

135672-75-2

diethyldithiophosphoric acid N,N'-diphenylguanidinium salt

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;94%
102-06-7

diphenylguanidine

3405-89-8

2-(4-chloro-phenylsulfonyl)acetic acid

C13H13N3*C8H7ClO4S

Conditions
ConditionsYield
In methanol94%
2253-60-3

O,O-diphenyl phosphorodithioic acid

102-06-7

diphenylguanidine

135672-83-2

Dithiophosphoric acid O,O'-diphenyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;93%
102-06-7

diphenylguanidine

112330-33-3

3-methyl-4-nitroisoxazol-5(4H)-one

1,3-diphenylguanidinium 5-oxo-3-phenyl-4,5-dihydroisoxazole-4-nitronate

Conditions
ConditionsYield
In water93%
102-06-7

diphenylguanidine

106-51-4

p-benzoquinone

1550369-57-7

1-phenyl-2-(phenylamino)-1H-benzo[d]imidazol-6-ol

Conditions
ConditionsYield
In dichloromethane at 0 - 20℃; for 16h; regioselective reaction;93%
102-06-7

diphenylguanidine

2253-57-8

di-n-octyl dithiophosphate

56867-55-1

Dithiophosphoric acid O,O'-dioctyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;92%
102-06-7

diphenylguanidine

C13H13N3*C9H9ClO3

Conditions
ConditionsYield
In methanol92%
78-64-8

dithiophosphoric acid O,O'-dihexyl ester

102-06-7

diphenylguanidine

135672-84-3

Dithiophosphoric acid O,O'-dihexyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;91%
4474-60-6

methacryloyl isocyanate

102-06-7

diphenylguanidine

1,2-diphenyl-3-methacryloylcarbamoylguanidine

Conditions
ConditionsYield
91%
102-06-7

diphenylguanidine

14366-43-9

O,O-di-p-tolyl hydrogen phosphorodithioate

135672-86-5

Dithiophosphoric acid O,O'-di-p-tolyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;91%
102-06-7

diphenylguanidine

6028-46-2

C12H23O2PS2

135700-26-4

Dithiophosphoric acid O,O'-dicyclohexyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;90%
102-06-7

diphenylguanidine

113416-39-0

methyl 3-benzoyl-1-(4-methoxyphenyl)-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylate

1309922-94-8

9-benzoyl-8-hydroxy-2-imino-6-(4-methoxyphenyl)-1,3-diphenyl-1,3,6-triazaspiro[4.4]non-8-ene-4,7-dione

Conditions
ConditionsYield
In 1,2-dichloro-ethane for 1h; Reflux;89%
102-06-7

diphenylguanidine

1860-98-6

diethyl 2-methylpyrimidine-4,5-dicarboxylate

76240-18-1

ethyl 4-oxo-7-methyl-1-phenyl-2-(phenylimino)-1,3,6,8-tetraazaspiro<4.5>deca-6,9-diene-10-carboxylate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran Ambient temperature;88.5%
2253-59-0

dithiophosphoric acid O,O'-bis-decyl ester

102-06-7

diphenylguanidine

135672-87-6

Dithiophosphoric acid O,O'-didecyl ester; compound with N,N'-diphenyl-guanidine

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;88%
102-06-7

diphenylguanidine

3209-72-1

ethyl 5-methylisoxazole-3-carboxylate

103912-60-3

3-<(N1,N2-diphenylamidino)carbamoyl>-5-methylisoxazole

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 24h; Ambient temperature;88%
32650-55-8

O,O-diisoamylphosphorodithioic acid

102-06-7

diphenylguanidine

135672-82-1

N,N'-Diphenyl-guanidine; compound with dithiophosphoric acid O,O'-bis-(3-methyl-butyl) ester

Conditions
ConditionsYield
In chloroform for 0.25h; Ambient temperature;85%
50-00-0

formaldehyd

102-06-7

diphenylguanidine

1293386-46-5

3,5,9,11,15,17,21,23-octaphenyl-1,7,13,19-tetrathia-3,5,9,11,15,17,21,23-octaazacyclotetracosane-4,10,16,22-tetraimine

Conditions
ConditionsYield
With hydrogen sulfide; sodium butanolate In water; butan-1-ol at 40℃; for 4h;85%
102-06-7

diphenylguanidine

532-27-4

1-chloroacetophenone

N,1,5-triphenyl-1H-imidazol-2-amine

Conditions
ConditionsYield
With choline chloride; triethylamine; glycerol at 80℃; Reagent/catalyst; Green chemistry;85%
102-06-7

diphenylguanidine

583-53-9

1,2-dibromobenzene

31413-80-6

1-phenyl-2-phenylamino-1H-benzo[d]imidazole

Conditions
ConditionsYield
With potassium phosphate; palladium diacetate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate In toluene at 140℃; for 24h; Molecular sieve; Inert atmosphere; regiospecific reaction;84%
342793-00-4

(S)-1-isopropyl-pyrrolidine-2-carboxylic acid

102-06-7

diphenylguanidine

(S)-N-(N,N'-diphenylcarbamimidoyl)-1-isopropylpyrrolidine-2-carboxamide

Conditions
ConditionsYield
Stage #1: (S)-1-isopropyl-pyrrolidine-2-carboxylic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide for 5h;
Stage #2: diphenylguanidine In N,N-dimethyl-formamide at 0 - 20℃; for 16h;
84%
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Chemistry

Molecular Structure of 1,3-Diphenylguanidine (CAS NO.102-06-7):

IUPAC Name: 1,2-diphenylguanidine 
Empirical Formula: C13H13N3
Molecular Weight: 211.2624
H bond acceptors: 3
H bond donors: 3
Freely Rotating Bonds: 2
Polar Surface Area: 18.84Å2
Index of Refraction: 1.604
Molar Refractivity: 65.14 cm3
Molar Volume: 189.2 cm3
Surface Tension: 46.8 dyne/cm
Density: 1.11 g/cm3
Flash Point: 158.5 °C
Enthalpy of Vaporization: 58.18 kJ/mol
Boiling Point: 338.5 °C at 760 mmHg
Vapour Pressure: 9.81E-05 mmHg at 25°C
Melting point: 146-148 °C(lit.)
Water Solubility: slightly soluble
Merck: 14,3324
BRN: 1875653
InChI
InChI=1/C13H13N3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H,(H3,14,15,16)
Smiles
c1(NC(Nc2ccccc2)=N)ccccc1
EINECS: 203-002-1
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. Moisture sensitive
Product Categories: Industrial/Fine Chemicals; Organics; DIO - DIZCertified Reference Materials (CRMs);Alphabetic; Application CRMs; Titrimetry; Guanidines; Nitrogen Compounds; Organic Building Blocks

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 25mg/kg (25mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TETANY
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 143, Pg. 815, 1949.
guinea pig LD50 oral 250mg/kg (250mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 974, 1986.
guinea pig LDLo subcutaneous 200mg/kg (200mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TETANY
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 143, Pg. 815, 1949.
mammal (species unspecified) LDLo oral 250mg/kg (250mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene. Vol. 13, Pg. 87, 1931.
mouse LD50 intraperitoneal 25mg/kg (25mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 oral 150mg/kg (150mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: ATAXIA
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.
mouse LD50 unreported 258mg/kg (258mg/kg) BLOOD: NORMOCYTIC ANEMIA Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(7), Pg. 35, 1978.
rabbit LD50 oral 250mg/kg (250mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 974, 1986.
rabbit LD50 skin > 794mg/kg (794mg/kg)   National Toxicology Program Technical Report Series. Vol. NIH-95-3933,
rabbit LD50 unreported 246mg/kg (246mg/kg) BLOOD: NORMOCYTIC ANEMIA Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(7), Pg. 35, 1978.
rat LD50 intraperitoneal 75mg/kg (75mg/kg)   Medycyna Pracy. Industrial Medicine. Vol. 16, Pg. 35, 1965.
rat LD50 oral 323mg/kg (323mg/kg)   National Toxicology Program Technical Report Series. Vol. NIH-95-3933,
rat LD50 unreported 323mg/kg (323mg/kg) BLOOD: NORMOCYTIC ANEMIA Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(7), Pg. 35, 1978.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: HarmfulXn,DangerousN
Risk Statements : 
R22:Harmful if swallowed.;
R36/37/38:Irritating to eyes, respiratory system and skin.;
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.;
R62:Possible risk of impaired fertility.;
Safety Statements : 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.;
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.;
S61:Avoid release to the environment. Refer to special instructions / Safety data sheets.;
RIDADR: UN 3077 9/PG 3

Specification

 1,3-Diphenylguanidine , with CAS number of 102-06-7, can be called 1,3-Diphenylguanidine ; Dwufenyloguanidyna ; Diphenylguanidine ; DPG accelerator ; Guanidine, N,N'-diphenyl- ; Guanidine, 1,3-diphenyl- ; N,N'-Diphenylguanidine ; s-Diphenylguanidine ; Vulkazit . It is a white to cream-colored chalky powder. Bitter taste and slight odor. 1,3-Diphenylguanidine (CAS NO.102-06-7) behaves as an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Besides 1,3-Diphenylguanidine (CAS NO.102-06-7) is incompatible with strong oxidizers.