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CAS No.: | 109-59-1 |
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Name: | 2-ISOPROPOXYETHANOL |
Article Data: | 17 |
Molecular Structure: | |
Formula: | C5H12 O2 |
Molecular Weight: | 104.149 |
Synonyms: | Ethanol,2-isopropoxy- (6CI,7CI,8CI); 2-Isopropoxyethanol; 2-Isopropyloxyethanol;2-[(1-Methylethyl)oxy]ethanol; Dowanal EiPAT; Ethylene glycol isopropyl ether;Ethylene glycol monisopropyl ether; Ethylene glycol monoisopropyl ether;Isopropyl Cellosolve; Isopropyl Oxitol; NSC 1259; Ucar AC; b-Hydroxyethyl isopropyl ether |
EINECS: | 203-685-6 |
Density: | 0.903 |
Melting Point: | -60 °C |
Boiling Point: | 131.8 °C at 760 mmHg |
Flash Point: | 43 ºC |
Solubility: | Toxicity">
Stability
Toxicology
Toxicity |
Appearance: | clear colorless liquid |
Hazard Symbols: | |
Risk Codes: | R20/21;R36 |
Safety: | Moderately toxic by skin contact and intraperitoneal routes. Mildly toxic by inhalation and ingestion. A skin and eye irritant. When heated to decomposition it emits acrid smoke and fumes. See also GLYCOL ETHERS. |
Transport Information: | UN 2929 |
PSA: | 29.46000 |
LogP: | 0.40370 |
Conditions | Yield |
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With boron trifluoride at 80℃; | |
With hydro silicate bei Siedehitze; | |
With ortho-tungstic acid at 90 - 95℃; under 7355.08 - 8826.09 Torr; |
Conditions | Yield |
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With sodium carbonate |
Conditions | Yield |
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(i) Na, (ii) LiAlH4; Multistep reaction; |
oxirane
ethanol
isopropyl alcohol
tert-butyl alcohol
A
2-ethoxy-ethanol
B
2-(1-methylethoxy)-ethanol
C
tert-butyl glycidyl ether
Conditions | Yield |
---|---|
Trimethyl borate; hydrogen fluoride In water at 30℃; for 0.166667h; |
bisoprolol fumarate
A
2-(1-methylethoxy)-ethanol
Conditions | Yield |
---|---|
With hydrogenchloride In water at 70.04℃; Kinetics; Mechanism; Temperature; Concentration; |
bisoprolol fumarate
A
2-(1-methylethoxy)-ethanol
Conditions | Yield |
---|---|
With hydrogen bromide; potassium bromide In water at 70.04℃; Kinetics; Mechanism; Temperature; Reagent/catalyst; |
bisoprolol fumarate
A
2-(1-methylethoxy)-ethanol
Conditions | Yield |
---|---|
With hydrogen iodide; potassium iodide In water at 70.04℃; Kinetics; Mechanism; Temperature; Reagent/catalyst; |
2-(1-methylethoxy)-ethanol
methanesulfonyl chloride
methanesulfonic acid 2-isopropoxyethyl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1.5h; Cooling with ice; | 100% |
With triethylamine In dichloromethane at 20℃; | 80% |
With triethylamine In dichloromethane at 0 - 20℃; for 3h; | 80% |
2-(1-methylethoxy)-ethanol
[Y4(μ3,η2-OC2H4OCH(CH3)2)3(μ,η2-OC2H4OCH(CH3)2)2(η1-OC2H4OCH(CH3)2)4(μ,η1-OC2H4OCH(CH3)2)3]2
Conditions | Yield |
---|---|
In toluene reactions carried out under argon; Y5O(OCH(CH3)2)13 reacted with 2-isopropoxyethanol in toluene at room temp. for 12 h; elem. anal.; | 99% |
2-(1-methylethoxy)-ethanol
Conditions | Yield |
---|---|
Stage #1: 2-(1-methylethoxy)-ethanol With sodium In tetrahydrofuran at 0℃; for 0.5h; Stage #2: 8-bromo-7-(4-chlorobenzyl)-3-methyl-1-(3-(tetrahydro-2H-pyran-2-yloxy)propyl)-1H-purine-2,6(3H,7H)-dione In tetrahydrofuran at 20℃; for 16h; | 95.2% |
1. | skn-rbt 20 mg/24H MOD | 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,627. | ||
2. | eye-rbt 500 mg/24H MLD | 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,627. | ||
3. | orl-rat LD50:5660 mg/kg | AIHAAP American Industrial Hygiene Association Journal. 30 (1969),470. | ||
4. | ihl-rat LC50:3100 mg/m3/4H | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,67. | ||
5. | ipr-rat LD50:800 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,67. | ||
6. | orl-mus LD50:4900 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,67. | ||
7. | ihl-mus LC50:1930 ppm/7H | JIHTAB Journal of Industrial Hygiene and Toxicology. 25 (1943),157. | ||
8. | ipr-mus LD50:1860 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,67. | ||
9. |