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16357-69-0

16357-69-0

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16357-69-0 Usage

Chemical Properties

White to brown solid

Uses

4-Amino-5-pyrimidinecarbonitrile may be used as a monodentate ligand to prepare metal complexes of Co(II), Ni(II), Cu(II) and Pd(II) ions. It may be used as a reactant to prepare 1H-pyrimido[4,5-d]pyrimidine-2,4-dione.

General Description

4-Amino-5-pyrimidinecarbonitrile (APC) is a pyrimidine derivative that has been synthesized via three-component reaction between benzaldehyde, benzamidine hydrochloride and malononitrile. The infrared, 1H NMR, 13C NMR and mass spectra of APC have been recorded.

Check Digit Verification of cas no

The CAS Registry Mumber 16357-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,5 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16357-69:
(7*1)+(6*6)+(5*3)+(4*5)+(3*7)+(2*6)+(1*9)=120
120 % 10 = 0
So 16357-69-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H4N4/c6-1-4-2-8-3-9-5(4)7/h2-3H,(H2,7,8,9)

16357-69-0 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
  • Packaging
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  • Detail

  • Alfa Aesar

  • (43627)  4-Aminopyrimidine-5-carbonitrile, 97%   

  • 16357-69-0

  • 0.25g

  • 163.0CNY

  • Detail

  • Alfa Aesar

  • (43627)  4-Aminopyrimidine-5-carbonitrile, 97%   

  • 16357-69-0

  • 1g

  • 651.0CNY

  • Detail

  • Alfa Aesar

  • (43627)  4-Aminopyrimidine-5-carbonitrile, 97%   

  • 16357-69-0

  • 5g

  • 3249.0CNY

  • Detail

  • Aldrich

  • (479969)  4-Amino-5-pyrimidinecarbonitrile  96%

  • 16357-69-0

  • 479969-1G

  • 405.99CNY

  • Detail

  • Aldrich

  • (479969)  4-Amino-5-pyrimidinecarbonitrile  96%

  • 16357-69-0

  • 479969-5G

  • 1,237.86CNY

  • Detail

16357-69-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-?Amino-?5-?pyrimidinecarbonitrile

1.2 Other means of identification

Product number -
Other names 4-Aminopyrimidine-5-carbonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16357-69-0 SDS

16357-69-0Relevant articles and documents

An improved preparation of 4-aminopyrimidine-5-carboxaldehyde

Bell, Thomas W.,Beckles, Daniel L.,Debetta, Michele,Glover, Brian R.,Hou, Zheng,Hung, Kar-Yan,Khasanov, Alisher B.

, p. 321 - 325 (2002)

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Heterocyclic compound used as MNK inhibitor

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Paragraph 0167, (2019/01/08)

The invention relates to a heterocyclic compound, a pharmaceutical composition containing the heterocyclic compound, a preparation method thereof, and application thereof used as a mitogen activated protein kinase interacting kinase 1 and 2-MNK1/MNK2 inhibitor. The inhibitor is the heterocyclic compound as shown in the formula (I), or its pharmaceutically acceptable salt, prodrug, solvent compound, polycrystal, isomer, stable isotope derivative or a pharmaceutical composition containing the heterocyclic compound. The compound of the invention can be used for treating or preventing MNK-mediatedrelated diseases, such as cancers.

PYRIDO PYRIMIDINES

-

Page/Page column 79, (2012/07/28)

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.

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