108-60-1 Usage
Description
Bis-(2-chloroisopropyl) ether is a byproduct in the synthesis of ethylene and propylene glycol that has been found in municipal drinking water in the United States and waterways in the Netherlands where it is considered a persistent organic pollutant (POP). It is mutagenic in the S. typhimurium strains TA 1535 and TA 100 but lacks mutagenic activity in mice.
Chemical Properties
Different sources of media describe the Chemical Properties of 108-60-1 differently. You can refer to the following data:
1. Clear Colourless Oil
2. Dichloroisopropyl ether is a colorless liquid.
Physical properties
Colorless to light brown oily liquid. Verschueren (1983) reported an odor threshold concentration
of 320 ppb.
Uses
Different sources of media describe the Uses of 108-60-1 differently. You can refer to the following data:
1. Bis(2-chloroisopropyl)ether is used as a sol vent for resins, waxes, and oils, and inorganic synthesis.
2. Apparently used as a nematocide in Japan but is not registered in the U.S. for use
as a pesticide.
3. Bis(2-chloroisopropyl) Ether is an organochlorine pesticide. Bis(2-chloroisopropyl) Ether is used as a nematicide to control parasitic nematodes in agriculture.
General Description
Colorless to light brown liquid. Odor threshold concentration 200 μg/L.
Air & Water Reactions
Subject to peroxidation in air. Insoluble in water.
Reactivity Profile
BIS(2-CHLOROISOPROPYL)ETHER oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979 p.151-154, 164].
Health Hazard
Bis(2-chloroisopropyl)ether exhibited moderately toxic and carcinogenic actions intest animals. The acute inhalation toxicity of this compound is considerably lowerthan those of bis(chloromethyl)ether and bis(chloroethyl)ether. Exposure to its vapors cancause irritation of the eyes and upper respiratory tract. Inhalation of 700 ppm of this com pound in air for 5 hours proved fatal to ratsThe oral toxicity of bis(2-chloroisopropyl)ether in rats was found to be moderate, withan LD50 value of 240 mg/kg.The compound is carcinogenic to animals.Although there is no evidence of its carcino genicity in humans, exposure may cause lungcancer.
Fire Hazard
BIS(2-CHLOROISOPROPYL)ETHER is combustible.
Potential Exposure
BCIE was previously used as a solvent
and as an extractant. It may be formed as a by-product of
propylene oxide production. It has been found in industrial
waste water and in natural water.
Source
No MCLGs or MCLs have been proposed, however, a DWEL of 1
mg/L was recommended (U.S. EPA, 2000).
A waste by-product in the manufacture of propylene glycol (quoted, Verschueren, 1983).
Environmental Fate
Biological. When bis(2-chloroisopropyl)ether (5 and 10 mg/L) was statically incubated
in the dark at 25°C with yeast extract and settled domestic wastewater inoculum, complete
biodegradation was achieved after 14 days (Tabak et al., 1981).Chemical/Physical. Kollig (1993) reported that bis(2-chloroisopropyl)ether is subject
to hydrolysis forming hydrochloric acid and the intermediate (2-hydroxy-isopropyl-2-
chloroisopropyl)ether. The latter undergoes further hydrolysis yielding bis
Shipping
UN2490 Dichloroisopropyl ether, Hazard Class:
6.1; Labels: 6.1—Poisonous materials.
Incompatibilities
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. It may form dangerous
peroxides upon standing; may explode when heated.
Waste Disposal
Use special incinerator due to
high HCl content, such as seagoing incinerator ships.
Check Digit Verification of cas no
The CAS Registry Mumber 108-60-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 108-60:
(5*1)+(4*0)+(3*8)+(2*6)+(1*0)=41
41 % 10 = 1
So 108-60-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H12Cl2O/c1-5(3-7)9-6(2)4-8/h5-6H,3-4H2,1-2H3/t5-,6+
108-60-1Relevant articles and documents
CARBON MEMBRANE HAVING BIOLOGICAL MOLECULE IMMOBILIZED THEREON
-
, (2009/08/14)
Disclosed is a biological molecule-immobilized carbon membrane which comprises a porous carbon membrane and a biological molecule (e.g., an enzyme) immobilized on the carbon membrane, wherein the porous carbon membrane has three-dimensional cancellous pores through which fluid can permeate. The carbon membrane can have a large amount of a biological molecule (e.g., an enzyme) immobilized thereon and can also have a higher level of enzymatic activity or the like compared to a conventional one. Therefore, the carbon membrane is useful as an electrode for a bio-sensor or a bio-fuel cell.
Three Component Reactions. XVI. Halogenation of Alk-1-enes in the Presence of Ethylene Oxide and Propylene Oxide
Beger, J.,Schiefer, H.,Scheller, D.
, p. 719 - 728 (2007/10/02)
The products of the chlorination of alk-1-enes in the presence of ethylene oxide and propylene oxide were investigated in relation to products of the chlorination in the presence of corresponding chloroalcohols 4 and 5.Isomers dominating in the Markovnikov orientation were found in all cases.Two of the three pairs of diastereomeric bischloropropylethers expected for the chlorination of propene in the presence of propylene oxide were identified by capillar GLC and 13C n.m.r. spectroscopy.
