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Guanidinium sulfate, with the chemical formula (CH6N3)2(SO4)2, is a salt that serves as a denaturant in protein purification and a chaotropic agent, disrupting the structure of macromolecules such as proteins and nucleic acids. It is highly soluble in water and is used in various applications across different industries due to its strong chaotropic effect.

1184-68-5

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1184-68-5 Usage

Uses

Used in Biochemistry and Molecular Biology Research:
Guanidinium sulfate is used as a denaturant for protein purification, facilitating the separation and isolation of proteins by disrupting their native structure and interactions with other molecules.
Used in Agricultural Chemical Production:
Guanidinium sulfate is utilized in the production of agricultural chemicals, contributing to the development of effective and efficient products for crop protection and enhancement.
Used in Organic Synthesis:
Guanidinium sulfate is employed as a reagent or catalyst in various organic synthesis processes, enabling the synthesis of complex organic compounds and pharmaceuticals.
Safety Precautions:
It is crucial to handle guanidinium sulfate with care due to its toxicity and potential to cause irritation to the skin, eyes, and respiratory system. Proper safety measures, such as wearing protective gear and working in a well-ventilated area, should be taken to minimize exposure and ensure the safety of researchers and workers.

Check Digit Verification of cas no

The CAS Registry Mumber 1184-68-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1184-68:
(6*1)+(5*1)+(4*8)+(3*4)+(2*6)+(1*8)=75
75 % 10 = 5
So 1184-68-5 is a valid CAS Registry Number.
InChI:InChI=1/2CH5N3.H2O4S/c2*2-1(3)4;1-5(2,3)4/h2*(H5,2,3,4);(H2,1,2,3,4)

1184-68-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name carbamimidoylazanium,sulfate

1.2 Other means of identification

Product number -
Other names Cuanidine sulfate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1184-68-5 SDS

1184-68-5Relevant academic research and scientific papers

Carbonyl and oxalyl bridged bis(l,5-diaminotetrazole)-based energetic salts

Joo, Young-Hyuk,Twamley, Brendan,Shreeve, JeaN'Ne M.

, p. 9097 - 9104 (2009)

High density energetic salts containing nitrogen rich cations and carbonyl- or oxalylbis(diamino-tetrazole) anions, which were obtained from cyanogen azide and hydrazine, were readily synthesized. In every case, a new family of energetic salts 3-14 were c

Guanidinium sulfates as directors of noncentrosymmetric structures

Brummel, Beau R.,Lee, Kinsey G.,Kolis, Joseph W.,Whitehead, Daniel C.,McMillen, Colin D.

, p. 1643 - 1656 (2021)

The structures of seven compounds based on guanidinium cations, isolated sulfate anions, and additional organic cations and solvent molecules are reported. All seven compounds, (C(NH2)3)2(SO4) (1), (C(NH2)3)3(C5H6N)(SO4)2(2), (C(NH2)3)3(C5H6N)(SO4)2·H2O (3), (C(NH2)3)3(C5H6N)(SO4)2·CH3OH (4), (C(NH2)3)11(C5H6N)(SO4)6·2.5C2H5OH (5), (C(NH2)3)3(C6H16N)(SO4)2(6), and (C(NH2)3)2(C20H26N2O2)(SO4)2(7) crystallize without a center of symmetry, and are built of related motifs of six-membered ringsviahydrogen bonding of three guanidinium cations and three sulfate anions. These six-membered rings form extended sheets and frameworks through additional hydrogen bonding interactions. The presence of additional cations and solvent molecules in varying ratios add structural diversity by modifying the guanidinium sulfate frameworks, but retaining the acentricity of the structures. The study reveals a remarkable tendency for these guanidinium sulfate frameworks to crystallize without a center of symmetry, and furthermore, in polar or chiral space groups. This provides a potential pathway for the use of hydrogen bonding interactions to design structures having interesting physical or nonlinear optical properties.

Thermally stable energetic salts based on 3-nitramino-4-tetrazolefurazan

Huang, Haifeng,Shi, Yameng,Li, Ying,Liu, Yanfang,Yang, Jun

, p. 64568 - 64574 (2016/07/21)

In order to develop new energetic materials with high energy and low sensitivity, a series of nitrogen-rich energetic salts based on 3-nitramino-4-tetrazolefurazan were conveniently synthesized through nitration, neutralization and metathesis reaction. All energetic salts were fully characterized by NMR (1H, 13C), IR and elemental analysis. Furthermore, ammonium salt (2) was confirmed by 15N NMR and hydroxylammonium salt (5) was confirmed by single-crystal X-ray diffraction. Salt 5 crystallized in triclinic space group P1 with four hydroxylammonium cations and two NATF anions per unit cell at a density of 1.815 g cm-3. The densities of the salts are in the range of 1.621 (6) to 1.815 g cm-3 (5). Due to the two nitrogen-rich cations in the salts, they show high positive enthalpies of formation falling between 299.2 kJ mol-1 (2) and 1040.6 kJ mol-1 (9). All the salts show good thermal stabilities with the decomposition temperatures ranging from 203 °C (4) to 284 °C (6). The impact sensitivities of the energetic salts lie between 5 J (2 and 5) and >40 J (6, 7, 8) and their friction sensitivities range from 108 N (4) to >360 N (6). Their detonation performances were calculated according to Kamlet-Jacobs equations. The detonation pressures of the synthesized energetic salts were found to be in the range of 21.1 GPa (6) to 34.7 GPa (5) and their detonation velocities are between 7117 m s-1 (6) and 8826 m s-1 (5).

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

-

, (2010/03/02)

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

Water-soluble derivatives of camptothecin/homocamptothecin

-

, (2008/06/13)

Camptothecin and homocamptothecin analogs and derivatives are provided incorporating alkylamine and polyalkylamine moieties.

Reaction of Bis(trimethylsilyl) Sulfate with Hexamethyldisalazane, Acetamide, and Guanidine Hydrochloride

Belousova,Vlasova,Voronkov

, p. 397 - 399 (2007/10/03)

Bis(trimethylsilyl) sulfate acts as a donor of trimethylsilyl group in the reaction with hexamethyldisilazane, which results in formation of tris(trimethylsilyl)amine. In the reaction with acetamide it acts as a donor of SO3. The latter inserts into the O-H bond of the imide form of acetamide; the final reaction products are acetonitrile and sulfuric acid. The reaction of bis(trimethylsilyl) sulfate with guanidine hydrochloride leads to trimethylchlorosilane and guanidine sulfate.

Heterocyclic amidino substituted ureas and their pharmaceutical uses

-

, (2008/06/13)

This invention relates to methods for the prophylactic and curative treatment of gastrointestinal and cardiovascular disorders and parasitic infections in humans and animals, using a class of hetrocyclic amidino substituted urea and thiourea compounds, a novel class of heterocyclic amidino substituted urea and thiourea compounds and pharmaceutical compositions and animal feed additives including the same.

Imaging agent and method of use

-

, (2008/06/13)

A new radiopharmaceutical composition for use in nuclear medicine comprises a radioiodinated meta-iodobenzylguanidine. The composition is used as an imaging agent for the heart, adrenal medulla, and tumors of the adrenal medulla and can be used for treatm

Guanidinium salts, processes for their manufacture as well as microbicidal preparations containing these compounds

-

, (2008/06/13)

Guanidinium salts having the formula STR1 wherein R1 and R2 are linear alkyl residues, X is an anion, and n is 1 or 2, which possess excellent microbicidal properties, particularly against organisms which have become resistant against other active materials. Methods for preparation of the compounds and solutions containing same are disclosed.

Process for preparing guanidine

-

, (2008/06/13)

A process is described for preparing guanidine by separating guanidine from a process stream obtained in a urea synthesis process, wherein ammonia and carbon dioxide are reacted at a high temperature and a high pressure. The process stream includes a urea synthesis effluent from a urea synthesis zone, a solution obtained by separating unreacted materials from the effluent, a concentrate of the solution or a mother liquor derived from a urea crystallization zone.

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