141377-53-9Relevant academic research and scientific papers
Double bond formation based on nitroaldol reaction and radical elimination: A prototype segment connection method for the total synthesis of nigricanoside A dimethyl ester
Tsunoda, Takayuki,Fujiwara, Kenshu,Okamoto, Satoshi,Kondo, Yoshihiko,Akiba, Uichi,Ishigaki, Yusuke,Katoono, Ryo,Suzuki, Takanori
, p. 1846 - 1850 (2018)
During the course of our studies toward the total synthesis of nigricanoside A dimethyl ester, a prototype method for the connection of the left- and right-half segments at the C9′–C10′ double bond was developed using a model system. The method was based
Enantioselective Henry reaction catalyzed with copper(II)-iminopyridine complexes
Blay, Gonzalo,Climent, Estela,Fernandez, Isabel,Hernandez-Olmos, Victor,Pedro, Jose R.
, p. 1603 - 1612 (2007)
Copper complexes of chiral iminopyridines prepared from camphane-derived ketones and picolylamine catalyzed the enantioselective Henry (nitroaldol) reaction between nitromethane and a number of aromatic and aliphatic aldehydes with high yields and good en
Asymmetric henry reactions of aldehydes using chiral biaryl-based bis(thiourea) organocatalysts
Nakayama, Yuki,Hidaka, Yusaku,Ito, Katsuji
, p. 883 - 885 (2013)
Biaryl-based bis(thiourea) was found to be an efficient organocatalyst for the asymmetric Henry reaction. High enantioselectivity of up to 93% ee was obtained for the reaction of nitromethane with aryl aldehydes when the combination of N,O-bis(trimethylsi
Effects of rare earth metals on the catalytic asymmetric nitroaldol reaction
Sasai, Hiroaki,Suzuki, Takeyuki,Itoh, Noriie,Arai, Shigeru,Shibasaki, Masakatsu
, p. 2657 - 2660 (1993)
Various asymmetric rare earth complexes have been prepared from rare earth metal trichlorides such as YCl3, LaCl3, PrCl3, NdCl3, SmCl3, EuCl3, GdCl3, TbCl3 and YbClsu
Copper(II) complexes of 2-(pyridine-2-yl)imidazolidine-4-thione derivatives for asymmetric Henry reactions
Nováková, Gabriela,Drabina, Pavel,Svoboda, Jan,Sedlák, Milo?
, p. 791 - 796 (2017)
The preparation of a new series of 2-(pyridine-2-yl)imidazolidine-4-thione derivatives is described. Their corresponding copper(II) complexes were found to be highly enantioselective catalysts for asymmetric Henry reactions (up to 98% ee). Immobilization
Chiral monometallic lanthanide(III) salt complexes are arrayed acid-base networks for enantioselective catalysis: A direct, nitroaldol (Henry) reaction
Saa, Jose M.,Tur, Fernando,Gonzalez, Jose,Vega, Manuel
, p. 99 - 106 (2006)
Shelf stable, but kinetically labile, highly symmetric, 3:1 complexes of 3,3′-bis-diethylaminomethyl-2,2′-dihydroxy-1,1′-dinaphthalene 1 ('binolam') with lanthanide(III) triflates are easily available compounds possessing an extended array of acid and bas
l-Proline derived arylmethanamine ligands and their application in the copper-catalyzed asymmetric Henry reaction: a rare example of a Cu-complex with a dicopper tetraacetate core
Niedziejko, Piotr,Szewczyk, Magdalena,Kalicki, Przemys?aw,Ka?uza, Zbigniew
, p. 1083 - 1094 (2015)
A series of novel epimeric arylmethanamine ligands were synthesized from l-proline. Both epimers were subsequently examined in the copper(II)-catalyzed asymmetric Henry reaction. Product yield and stereoselectivity up to 92% ee indicated that the (S,S)-epimer was superior to the diamine with an (S,R)-configuration. An enhancement of enantioselectivity driven by the formation of a Cu(II) complex with a dicopper tetraacetate core was discovered. Two types of crystalline Cu(II) complexes were isolated, and their structures were established by X-ray analyses.
Enantioselective Henry reactions under dual Lewis acid/amine catalysis using chiral amino alcohol ligands
Palomo, Claudio,Oiarbide, Mikel,Laso, Antonio
, p. 3881 - 3884 (2005)
(Chemical Equation Presented) A simple assembly of commercially available materials, namely, zinc triflate (Zn-(OTf)2), a tertiary amine base (iPr2EtN), and reusable (+)-N-methylephedrine, effectively activates the Henry reaction bet
Tin(II)chloride mediated addition reaction of bromonitromethane to aldehydes
Mahasneh, Ali S.
, p. 416 - 418 (2005)
Bromonitromethane adds to aliphatic aldehydes in the presence of tin(II) chloride to yield β-nitro alcohols via a Reformatsky-type reaction in high yields, while aromatic aldehydes give low yields. The products were characterized by IR, NMR, and mass spectroscopy and by elemental analysis.
An efficient synthetic approach towards a single diastereomer of (2R,3R)-N 2,N 3-bis((S)-1-phenylethyl)butane-2,3-diamine via metalation and demetalation
Cho, Juhyun,Nayab, Saira,Jeong, Jong Hwa
, p. 9 - 17 (2020)
Abstract: A facile synthetic approach has been adopted towards the synthesis of (2R,3R)-N2,N3-bis((S)-1-phenylethyl)butane-2,3-diamine via demetalation of its dichloro Zn(II) complex, which itself was separated from a mixture of dias
