16232-41-0

Basic information

• Product Name: 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine
• Synonyms: 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine;6-methyl-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
• CAS NO: 16232-41-0
• Molecular Formula: C₁₃H₁₀N₂O
• Molecular Weight: 210.23
• Mol File: 16232-41-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 411.5°Cat760mmHg
• Flash Point: 202.7°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 5.56E-07mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine(16232-41-0)
• EPA Substance Registry System: 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine(16232-41-0)

Safety Data

• Hazardous Substances Data: 16232-41-0(Hazardous Substances Data)

Usage

General Description

3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine is a chemical compound with the molecular formula C13H10N2O. It is a pyridine derivative with a cyano group, a hydroxy group, a methyl group, and a phenyl group attached to the pyridine ring. 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine is a synthetic intermediate that is commonly used in the production of pharmaceuticals, agrochemicals, and other organic compounds. It has the potential to exhibit biological activity and may be used as a building block in the synthesis of various functional materials. Additionally, 3-Cyano-2-hydroxy-6-methyl-4-phenylpyridine is considered to be hazardous if ingested or inhaled, and appropriate safety precautions should be taken when handling this substance.

InChI:InChI=1/C13H10N2O/c1-9-7-11(10-5-3-2-4-6-10)12(8-14)13(16)15-9/h2-7H,1H3,(H,15,16)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 93-91-4 1-phenylbutan-1,3-dione 
• 107-91-5 cyanoacetic acid amide 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 100-39-0 benzyl bromide 
• 75-56-9 methyloxirane 
• 709-79-5 (E)-2-cyano-3-phenylacrylamide 
• 67-64-1 acetone 
• 100-52-7 benzaldehyde 
• 74360-15-9 1,6-diphenyl-4-methyl-2-(1H)pyrimidinethione 
• 78564-23-5 6-methyl-4-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 1896-62-4 (E)-benzalacetone 
• 41808-21-3 sodium salt of α-cyanoacetamide 
• 1817-57-8 4-phenyl-3-butyne-2-one 

Downstream Products

• 60847-55-4 1,6-dimethyl-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 
• 63404-83-1 6-methyl-4-phenyl-pyridin-2-ol 
• 60847-69-0 2-chloro-6-methyl-4-phenyl-nicotinonitrile 
• 1607833-75-9 3-amino-6-methyl-4-phenylpyridine-2(1H)-one 
• 57162-19-3 6-methyl-2-oxo-4-phenyl-1,2-dihydropyridine-3-carboxamide 
• 117209-88-8 3-Cyano-6-methyl-4-phenylpyridin 

Relevant articles and documents

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Synthesis and Photophysical Properties of 3-Amino-4-arylpyridin-2(1 H)-ones

A method has been developed for the preparation of oxazolo-[5,4- b ]pyridin-2(1 H)-ones based on the Hoffmann reaction of 2-oxo-1,2-dihydropyridine-3-carboxamides. Hydrolysis of oxazolo[5,4- b ]pyridin-2(1 H)-ones and the Hoffmann reaction of 2-oxo-1,2-dihydropyridine-3-carboxamides yielded 3-aminopyridin-2(1 H)-ones, including 4-aryl substituted derivatives in the series, for which effective phosphors with a quantum yield of up to 0.78 were detected. Photophysical properties of 3-aminopyridin-2(1 H)-ones were studied by UV and luminescence spectroscopy methods, and the relationship between their structure and photophysical properties was revealed.

One-Pot Synthesis of 3-Cyano-2-pyridones

A versatile synthesis of 3-cyano-2-pyridones via a one-pot, four-component condensation of ethyl cyanoacetate, ketones, aldehydes, and ammonium acetate under very mild conditions has been developed. This method provides rapid access to this type of valuab

AZAINDAZOLES

Herein are disclosed azaindazoles of formula (I), (I), where the various groups are defined herein, and which are useful for treating cancer.