17798-13-9

Upstream product

• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 24395-14-0 (R)-2-phenyl-N-tosylaziridine 
• 95-47-6 o-xylene 
• 20989-17-7 Phenylglycinol 
• 98-59-9 p-toluenesulfonyl chloride 
• 67-56-1 methanol 
• 107-05-1 3-chloroprop-1-ene 
• 40949-56-2 N-(p-toluenesulphonylimino)pyridinium ylide 
• 100-42-5 styrene 
• 473-34-7 N,N-dichloro-p-toluenesulfonamide 
• 70-55-3 toluene-4-sulfonamide 
• 96-09-3 styrene oxide 
• 127-65-1 chloroamine-T 
• 149286-01-1 2-(N-tosylamino)-1-phenyl-1-ethanol 

Downstream Products

• 5450-75-9 4-methyl-N-(2-phenylethyl)benzenesulfonamide 

Relevant academic research and scientific papers

Regio- and stereoselective ring opening of epoxides and aziridines using zirconyl chloride: An efficient approach for the synthesis of β-chlorohydrins and β-chloroamines

Zirconyl chloride mediated regio- and stereoselective ring opening of epoxides and aziridines at room temperature affords the corresponding β-chlorohydrins and β-chloroamines, respectively in high yields. Copyright

Ring opening of aziridines with silylated nucleophiles under neutral conditions

Ring-opening of aziridines with silylated nucleophiles in DMF without any catalysts afforded the corresponding products in good to excellent yields under extremely mild reaction conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

Unprecedented CO2-promoted aminochlorination of olefins with Chloramine-T

A new synthetic procedure for the aminochlorination of olefins for the synthesis of vicinal chloroamine derivatives using a combination of Chloramine-T and carbon dioxide is described. The method can be applied to a variety of olefins, including an electr

Regiospecific Three-Component Aminofluorination of Olefins via Photoredox Catalysis

Direct visible-light-mediated aminofluorination of styrenes has been developed with high regioselectivity. Shelf-stable N-Ts-protected 1-aminopyridine salt was used as the nitrogen-radical precursor, and the commercially available hydrogen fluoride-pyridi

Regioselective ring opening of aziridines with activated DMF complexes: A facile synthesis of β-haloamines

A wide variety of aziridines were converted to the corresponding β-haloamines using activated DMF complexes in good to excellent yields with high regioselectivity.

A phosphonium ylide as a visible light organophotoredox catalyst

A phosphonium ylide-based visible light organophotoredox catalyst has been designed and successfully applied to halohydrin synthesis using trichloroacetonitrile and epoxides. An oxidative quenching cycle by the ylide catalyst was established, which was confirmed by experimental mechanistic studies.

Use of trichloroacetonitrile as a hydrogen chloride generator for ring-opening reactions of aziridines

Regioselective ring-opening reactions of 2-aryl-N-tosylaziridines are described, in which hydrogen chloride is generated by photodegradation of trichloroacetonitrile. HCl adducts are obtained in high yields in 1,4-dioxane, whereas methanol adducts are pre

Visible-light-triggered Catalytic Halohydrin Synthesis from Epoxides and Trichloroacetonitrile by Copper and Iron Salts

Preparation of vicinal halohydrins, in which copper or iron chlorides catalyze the ring-opening reaction of epoxides with visible light effectively, is described. The use of trichloroacetonitrile as a halogen source enables catalytic HCl generation under the mild conditions. This method can also be applied to the aziridine ring-opening reaction.

Use of allylzinc halide as a source of halide: Differential addition of nucleophiles to Ts-aziridines and aldehydes under similar reaction conditions

We have observed that the allylic zinc halide under identical reaction conditions acts in different modes for different electrophiles. For Ts-aziridines the halide part of the allylic halide has been introduced as a nucleophile and for the carbonyl compou

Quickly FeCl3-catalyzed highly chemo- and stereo-selective [3 + 2] dipolar cycloaddition of aziridines with isothiocyanates

A FeCl3-catalyzed [3 + 2] cycloaddition reaction of aziridine with isothiocyanate was developed. The cycloaddition reaction was completed in two minutes with high chemoselectivity, stereoselectivity. 15 (tosylthiazolidin-2-ylidene)anilines were