23605-23-4

Basic information

• Product Name: 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE
• Synonyms: 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE;AKOS BBS-00004074;AKOS B015663;CHEMBRDG-BB 3015663;ART-CHEM-BB B015663;2-CHLORO-N-CYCLOHEXYL-ACETAMIDE >97%;2-chloro-N-cyclohexyl-ethanamide;2-chloro-N-cyclohexylacetamide(SALTDATA: FREE)
• CAS NO: 23605-23-4
• Molecular Formula: C₈H₁₄ClNO
• Molecular Weight: 175.66
• Mol File: 23605-23-4.mol
• Article Data: 69

Chemical Properties

• Melting Point: 109-111°C
• Boiling Point: 326.4 °C at 760 mmHg
• Flash Point: 151.2 °C
• Appearance: /
• Density: 1.1 g/cm³
• Vapor Pressure: 0.000216mmHg at 25°C
• Refractive Index: 1.484
• Storage Temp.: 2-8°C
• PKA: 13.97±0.20(Predicted)
• CAS DataBase Reference: 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE(23605-23-4)
• EPA Substance Registry System: 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE(23605-23-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 23605-23-4(Hazardous Substances Data)

Usage

General Description

2-CHLORO-N-CYCLOHEXYL-ACETAMIDE is a chemical compound with the molecular formula C8H15ClNO. It is a derivative of acetamide, with a chlorine atom attached to the 2-position and a cyclohexyl group attached to the nitrogen atom. 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceuticals. It has also been studied for its potential use as an anticonvulsant and analgesic agent. 2-CHLORO-N-CYCLOHEXYL-ACETAMIDE is considered to be a stable and relatively non-reactive compound under normal conditions, but it should be handled with care and in accordance with proper safety protocols due to its potential health hazards.

InChI:InChI=1/C8H14ClNO/c9-6-8(11)10-7-4-2-1-3-5-7/h7H,1-6H2,(H,10,11)

Upstream product

• 108-91-8 cyclohexylamine 
• 79-11-8 chloroacetic acid 
• 79-04-9 chloroacetyl chloride 
• 107-14-2 chloroacetonitrile 
• 110-83-8 cyclohexene 
• 108-93-0 cyclohexanol 
• 593-71-5 Chloroiodomethane 
• 3173-53-3 Cyclohexyl isocyanate 
• 75-36-5 acetyl chloride 
• 1440-61-5 N-chloroacetylmorpholine 
• 55112-46-4 3-hydroxy-2-(7-methoxy-[1,8]naphthyridin-2-yl)-2,3-dihydro-isoindol-1-one 
• 7572-29-4 dichloroethyne 
• 4960-82-1 dichlorodiacetamide 

Downstream Products

• 101785-23-3 (8-amino-[2]naphthyloxy)-acetic acid cyclohexylamide 
• 91564-81-7 (cyclohexylcarbamoyl-methyl)-phosphonic acid diethyl ester 
• 118989-51-8 1,4-bis(cyclohexylaminocarbonylmethyl)piperazine 
• 118989-50-7 N-cyclohexyl-2-(4-methyl-1-piperazinyl)acetamide 
• 110506-25-7 N-cyclohexyl-2-(4-nitrophenoxy)acetamide 
• 936632-81-4 1-deoxy-1-(6-{4-[(cyclohexylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide 
• 936632-85-8 1-deoxy-1-(2-chloro-6-{4-[(cyclohexylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide 
• 100875-61-4 2-(4-aminophenoxy)-N-cyclohexylacetamide 
• 686282-27-9 methyl 3-(2-(cyclohexylamino)-2-oxoethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate 
• 35801-69-5 cyclohexyloxazolidine-2,4-dione 
• 1190869-84-1 C₂₄H₄₀N₆O₄S 
• 1194373-20-0 2-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propylamino]-N-cyclohexylacetamide 
• 332157-56-9 2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-cyclohexylacetamide 

Relevant articles and documents

Synthesis, characterization and evaluation of novel ferrocenylmethylamine derivatives as cytotoxic agents

The present report describes a new series of amide functionalized 20- and 30-aminomethylferrocene derived from ferrocenylmethylamine. The compounds 1a-5a and 1b-5b were characterized by microanalysis, 1H, 13C NMR, UV–visible, fluorescence, FTIR, thermogravimetric and crystallographic techniques. The X-ray analysis demonstrated the ability of these molecules to form various intermolecular hydrogen bonding interactions, as verified by Hirshfeld surface analysis. All the compounds were evaluated against MCF 7, IMR 32, HepG2 and immortal L132 cell lines by MTT assay and the results were compared with cisplatin. Interestingly, many compounds were very active against all the investigated cell lines and proved to be more potent as cytotoxic agents than cisplatin. The western blot, gene expression, mitochondrial membrane potential and flow cytometry study were used to investigate the mode of action of these derivatives as antitumor agents. The results showed apoptotic property of the compounds by modulating inflammatory pathway against human tumor cells of different origin. We performed the density functional theory calculations and molecular docking to rationalize the experimental results.

New Coumarin derivatives as cholinergic and cannabinoid system modulators

In the last years, the connection between the endocannabinoid system (eCS) and neuroprotection has been discovered, and evidence indicates that eCS signaling is involved in the regulation of cognitive processes and in the pathophysiology of Alzheimer’s di

Substituted [1,2,4]triazolo[4,3-a]pyrazines as antidiabetics

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