25438-38-4Relevant academic research and scientific papers
A highly negatively charged γ-Keggin germanodecatungstate efficient for Knoevenagel condensation
Sugahara, Kosei,Kimura, Toshihiro,Kamata, Keigo,Yamaguchi, Kazuya,Mizuno, Noritaka
, p. 8422 - 8424 (2012)
A tetra-n-butylammonium (TBA) salt of a γ-Keggin -6-charged germanodecatungstate, [γ-H2GeW10O36] 6- (I), could act as an efficient homogeneous catalyst for Knoevenagel condensation of active methylene compounds with carbonyl compounds.
Crystal transformation in Mn(ii) metal-organic frameworks based on a one-dimensional chain precursor
Fan, Yong,Gong, Yiran,Jiang, Yansong,Liu, Rui,Wang, Li,Xu, Jianing
, p. 9540 - 9546 (2021/07/17)
The solvothermal reaction of Mn(ii) salts and 5-((4′-(tetrazol-5′′-yl)benzyl)oxy)isophthalic acid (H3L) affords an Mn(ii) based coordination polymer Mn(H2L)2(H2O)2(1), which possesses a one-dimensiona
Application of an Electrochemical Microflow Reactor for Cyanosilylation: Machine Learning-Assisted Exploration of Suitable Reaction Conditions for Semi-Large-Scale Synthesis
Sato, Eisuke,Fujii, Mayu,Tanaka, Hiroki,Mitsudo, Koichi,Kondo, Masaru,Takizawa, Shinobu,Sasai, Hiroaki,Washio, Takeshi,Ishikawa, Kazunori,Suga, Seiji
supporting information, p. 16035 - 16044 (2021/09/02)
Cyanosilylation of carbonyl compounds provides protected cyanohydrins, which can be converted into many kinds of compounds such as amino alcohols, amides, esters, and carboxylic acids. In particular, the use of trimethylsilyl cyanide as the sole carbon source can avoid the need for more toxic inorganic cyanides. In this paper, we describe an electrochemically initiated cyanosilylation of carbonyl compounds and its application to a microflow reactor. Furthermore, to identify suitable reaction conditions, which reflect considerations beyond simply a high yield, we demonstrate machine learning-assisted optimization. Machine learning can be used to adjust the current and flow rate at the same time and identify the conditions needed to achieve the best productivity.
Three Coordinated Organoaluminum Cation for Rapid and Selective Cyanosilylation of Carbonyls under Solvent-Free Conditions
Bhandari, Mamta,Prashanth, Billa,Rawat, Sandeep,Singh, Sanjay
, (2020/05/19)
The well-defined three coordinated electronically unsaturated cationic organoaluminum complex [({(2,6-iPr2C6H3N)P(Ph2)}2N)AlMe]+[MeB(C6F5)3]? (1), has been utilized to catalyze the cyanosilylation of aldehydes and ketones under mild and solvent-free conditions. Moreover, catalyst 1 showed high chemoselective cyanosilylation of aldehydes over ketones, nitriles and olefins. The multinuclear NMR investigations revealed that cyanosilylation proceeds via Lewis adduct formation between 1 and TMSCN thereby activating TMSCN (Si-CN bond) followed by nucleophilic attack of the carbonyl oxygen at the Si center of the activated silane and formation of the product.
Ultrathin Near-Infrared Light Activated Nano-Hotplate Catalyst
Wu, Xiangyang,Yeow, Edwin K. L.
, (2020/09/09)
A combined photothermal-catalytic system that contains a single active element, without using different entities for separate roles (catalytic vs photothermal), is designed here for efficient catalytic reactions. Herein, ultrathin (sub-6 nm) rectangular-l
Two polyoxoniobates-based ionic crystals as Lewis base catalysts for cyanosilylation
Li, Shujun,Ji, Panpan,Han, Shangning,Hao, Zhaomin,Chen, Xuenian
, (2019/11/28)
Two transition-metal containing heteropolyniobates, H[Ni(en)3]5[VNb12O40(VO)2]·15H2O (1) and H3[Cu(en)2]4[VNb12O40(VO)2]·13
Nanoceria as a recyclable catalyst/support for the cyanosilylation of ketones and alcohol oxidation in cascade
Garnes-Portolés, Francisco,Leyva-Pérez, Antonio,Rivero-Crespo, Miguel ángel
, p. 21 - 28 (2020/10/21)
The cyanosilylation of carbonyl compounds is a fundamental reaction in organic synthesis, to give cyanohydrins. Ketones are particularly reluctant to cyanosilane addition and require the action of a catalyst, and despite many soluble Br?nsted and Lewis ac
Preparation and application of ammonium salt
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Paragraph 0011, (2019/07/04)
The invention discloses an ammonium salt. The structural formula of the ammonium salt is shown in the specification. A synthesizing method of the ammonium salt comprises the following steps: refluxingand carrying out reaction between 5 mmol of 1-phenyl-1,
Low-valent magnesium(i)-catalyzed cyanosilylation of ketones
Wang, Weifan,Luo, Man,Li, Jia,Pullarkat, Sumod A.,Ma, Mengtao
supporting information, p. 3042 - 3044 (2018/03/28)
The magnesium(i) complex [(XylNacnac)Mg]2 was employed as a highly efficient catalyst for the cyanosilylation of a variety of ketones with trimethylsilyl cyanide under mild conditions. In contrast to the traditional stoichiometric us
Cyanosilylation reaction method using hydroboron to catalyze ketone
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Paragraph 0022, (2018/05/03)
The invention relates to the field of organic chemistry, aiming at solving the problems that the existing ketone-catalyzing cyanosilylation reaction has the defects of complicated catalyst structure,high preparation cost and more application limitations,
