26372-13-4

Usage

Uses

Used in Pharmaceutical Industry:
6-deoxy-L-galactonic acid is used as a building block for the synthesis of antibiotic and antifungal agents, contributing to the development of new drugs to combat resistant infections.
Used as a Chelating Agent:
6-deoxy-L-galactonic acid is used as a chelating agent for metal ions, which can be beneficial in various industrial processes, such as water treatment and metal recovery.
Used in Synthesis of Carbohydrate Molecules:
6-deoxy-L-galactonic acid is used as a precursor for the synthesis of novel carbohydrate molecules, expanding the range of available compounds for research and potential applications in various fields.

Upstream product

• 2438-80-4 L-Fucose 
• 4348-84-9 6-deoxy D-allose 
• 6014-42-2 L-rhamnose 
• 10035-10-6 hydrogen bromide 
• 7726-95-6 bromine 
• 6118-79-2 O-(α-D-galactopyranosyluronic acid)-(1->2)-L-rhamnose 
• 74-90-8 hydrogen cyanide 
• 13039-77-5 (2R,3R,4R)-2,3,4-trihydroxypentanal 
• 13039-78-6 5-deoxy-L-xylose aldehyde 
• 609-06-3 L-xylose 
• 131156-47-3 (3aS,3bR,7aS,8aS)-2,2,5,5-tetramethyltetrahydro-3aH-[1,3]dioxolo[4',5':4,5]furo[3,2-d][1,3]dioxane 
• 218621-71-7 6-hydroxy-2,2-dimethyl-5-(4-methylphenylsulfonyloxymethyl)-(3aS,5S,6R,6aS)-perhydrofuro[2,3-d][1,3]dioxole 
• 634-74-2 6-deoxy-D-glucose 
• 3615-37-0 D-Fucose 

Downstream Products

• 24286-28-0 (3S,4S,5R)-dihydro-3,4-dihydroxy-5-((1'S)-1'-hydroxyethyl)furan-2(3H)-one 
• 5456-69-9 L-fuconic acid amide 
• 6631-54-5 2-(L-galacto-1',2',3',4'-Tetrahydroxypentyl)benzimidazole 
• 6422-34-0 D-altromethylonic acid 
• 6631-54-5 2-(L-manno-1',2',3',4'-Tetrahydroxypentyl)benzimidazole 
• 636-41-9 2-methyl-1H-pyrrole 
• 488-31-3 L-arabinaric acid 
• 3615-37-0 D-Fucose 
• 7241-20-5 (2R,3S,4R)-pentane-1,2,3,4-tetrayl tetraacetate 
• 488-28-8 L-rhamnitol 
• 3615-41-6 L-Rhamnose 
• 634-74-2 6-deoxy-D-altrose 
• 64-18-6 formic acid 
• 849585-22-4 LACTIC ACID 

Relevant academic research and scientific papers

Efficient production of sugar-derived aldonic acids by Pseudomonas fragi TCCC11892

Aldonic acids are receiving increased interest due to their applications in nanotechnology, food, pharmaceutical and chemical industries. Microbes with aldose-oxidizing activity, rather than purified enzymes, are used for commercial production with limited success. Thus it is still very important to develop new processes using strains with more efficient and novel biocatalytic activities for the production of adonic acids. In the present study, Pseudomonas fragi TCCC11892 was found to be an efficient producer of aldonic acids, with the production of galactonic and l-rhamnonic acid by P. fragi reported for the first time. The semi-continuous production of maltobionic acid and lactobionic acid was developed for P. fragi TCCC11892, achieving a yield of over 90 g L?1 for the first 7 cycles. The excellent performance of P. fragi in the production of lactobionic acid (119 g L?1) was also observed when using waste cheese whey as an inexpensive fermentation medium. Scaling up of the above process for production of aldonic acids with P. fragi TCCC11892 cells should facilitate their commercial applications.

Substrate specificity of galactokinase from Streptococcus pneumoniae TIGR4 towards galactose, glucose, and their derivatives

Galactokinases (GalKs) have attracted significant research attention for their potential applications in the enzymatic synthesis of unique sugar phosphates. The galactokinase (GalKSpe4) cloned from Streptococcus pneumoniae TIGR4 presents a remarkably broad substrate range including 14 diverse natural and unnatural sugars. TLC and MS studies revealed that GalKSpe4 had relaxed activity towards galactose derivatives with modifications on the C-6, 4- or 2-positions. Additionally, GalKSpe4 can also tolerate glucose while glucose derivatives with modifications on the C-6, 4- or 2-positions were unacceptable. More interestingly, GalKSpe4 can phosphorylate l-mannose in moderate yield (43%), while other l-sugars such as l-Gal cannot be recognized by this enzyme. These results are very significant because there is rarely enzyme reported that can phosphorylate such uncommon substrates as l-mannose.

CATALYTIC DEHYDROGENATION OF REDUCING SUGARS IN ALKALINE SOLUTION

Aldoses in alkaline medium under the catalytic action of platinum of rhodium are converted into aldonic acids with high selectivity and with concomitant evolution of hydrogen gas.The dehydrogenation reaction has been studied for 25 different mono- and di-saccharides, and is generally applicable for reducing sugars.The influence of several reaction variables has been studied, leading to an adsorption model in which both the negatively charged O-1 and the close contact of H-1 with the catalyst surface are considered to be driving forces for the transfer of hydride from C-1 of the sugar to the catalyst.