14856-73-6

Basic information

• Product Name: (4-Nitrobenzyl)(trimethylsilyl) ether
• Synonyms: (4-Nitrobenzyl)(trimethylsilyl) ether;(4-Nitrobenzyloxy)trimethylsilane;1-Nitro-4-trimethylsiloxymethylbenzene;4-Nitro-1-[(trimethylsiloxy)methyl]benzene;4-Nitrobenzyl(trimethylsilyl) ether;Trimethyl(p-nitrobenzyloxy)silane
• CAS NO: 14856-73-6
• Molecular Formula: C₁₀H₁₅NO₃Si
• Molecular Weight: 225.32
• Mol File: 14856-73-6.mol
• Article Data: 80

Chemical Properties

• Boiling Point: >300 °C
• Appearance: /
• Density: 1.077±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (4-Nitrobenzyl)(trimethylsilyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Nitrobenzyl)(trimethylsilyl) ether(14856-73-6)
• EPA Substance Registry System: (4-Nitrobenzyl)(trimethylsilyl) ether(14856-73-6)

Safety Data

• Hazardous Substances Data: 14856-73-6(Hazardous Substances Data)

Upstream product

• 619-73-8 4-nitrobenzyl chloride 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 41468-11-5 sodium hydroxy(4-nitrophenyl)methanesulfonate 
• 4039-32-1 lithium hexamethyldisilazane 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 33861-17-5 phenyl trimethylsilyl selenide 
• 555-16-8 4-nitrobenzaldehdye 
• 75-77-4 chloro-trimethyl-silane 
• 139884-17-6 1-((methoxymethoxy)methyl)-4-nitrobenzene 
• 1058649-42-5 4-nitro-1-[(ethoxymethoxy)methyl]benzene 

Downstream Products

• 4457-41-4 4-nitrobenzyl benzoate 
• 56679-04-0 bis(p-nitrobenzyl)ether 
• 619-78-3 1-dichloromethyl-4-nitrobenzene 
• 18483-99-3 2-(4-nitrobenzyloxy)tetrahydro-2H-pyran 
• 13287-49-5 4-Nitro-benzylthiocyanat 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 100-14-1 4-nitrobenzyl chloride 
• 3145-86-6 4-nitrobenzyl iodide 
• 619-90-9 4-nitrobenzyl acetate 
• 30039-42-0 4-nitrobenzyl formate 
• 619-73-8 4-nitrobenzyl chloride 
• 62-23-7 4-nitro-benzoic acid 
• 89200-96-4 p-nitrobenzyldifluorophosphite 
• 555-16-8 4-nitrobenzaldehdye 

Relevant articles and documents

KF/clinoptilolite NPs: An efficient and heterogeneous catalyst for chemoselective silylation of alcohols and phenols

Potassium fluoride incorporated on clinoptilolite nanoparticles (KF/CP NPs) by ion exchanging is found to be an effective and inexpensive heterogeneous nanocatalyst for chemoselective silylation of alcohols and phenols with 1,1,1,3,3,3-hexamethyldisilazane (HMDS) at room temperature. Nano-powder of clinoptilolite (CP) was prepared using a planetary ball mill mechanically method and characterized by dynamic light scattering (DLS), X-ray powder diffraction (XRD) and scanning electron microscope (SEM) analyses. Almost all of products were obtained in high yields as well as short reaction times and the catalyst was also reused eight times without loss of its catalytic activity.

Fast and efficient method for Silylation of alcohols and phenols with HMDS in the presence of bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides

Bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides were used efficiently for rapid and efficient trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) in CH3CN. All reactions were carried out at room temperature within immediate-120?min timeframe to afford trimethylsilyl ether derivatives in high to excellent yields. Investigation of the results exhibited that the prepared bis-thiourea metal complexes show the activity as Co(tu)2Cl2> Ni(tu)2Cl2> Cu(tu)2Cl2> Zn(tu)2Cl2 in their silylation reactions.

Nano Fe3O4@ZrO2/SO42?: A highly efficient catalyst for the protection and deprotection of hydroxyl groups using HMDS under solvent-free condition

In this work, we introduce a new procedure for the protection and deprotection process of various types of alcohols and phenols by HMDS in the presence of nano magnetic sulfated zirconia (Fe3O4@ZrO2/SO42?) as a solid acid catalyst under very mild and solvent-free condition. This method has interesting advantages like short reaction times and a simple workup process. With regard to some outstanding benefits of this new heterogeneous catalyst such as excellent yield, reusability of the catalyst and easy thermal stability, high acidity, strong and excellent magnetic properties, this method can be very interesting in aspect of green chemistry Principles.