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Diethyl 4-formylmalonate, also known as Diethyl 4-formyl-2,4-dihydropyran-2,4-dicarboxylate, is a chemical compound with the molecular formula C11H14O5. It is a colorless to pale yellow liquid with a fruity odor and is slightly soluble in water but soluble in organic solvents. This versatile reagent is commonly used in organic synthesis to introduce the 4-formyl group into various compounds, making it a valuable component in the production of pharmaceuticals, agrochemicals, and specialty chemicals.

33142-25-5

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33142-25-5 Usage

Uses

Used in Pharmaceutical Synthesis:
Diethyl 4-formylmalonate is used as a reagent in pharmaceutical synthesis for its ability to introduce the 4-formyl group into compounds, which is crucial for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, Diethyl 4-formylmalonate is used as a key intermediate in the synthesis of various agrochemicals, contributing to the development of effective pest control agents and crop protection products.
Used in Specialty Chemicals Manufacturing:
Diethyl 4-formylmalonate is utilized as a versatile building block in the production of specialty chemicals, where its reactivity allows for the creation of unique compounds with specific applications in various industries.
Safety Precautions:
Due to its potentially hazardous nature if ingested, inhaled, or in contact with the skin, proper protective measures should be taken when handling Diethyl 4-formylmalonate. This includes wearing appropriate personal protective equipment and following safety guidelines to minimize risks during its use in chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 33142-25-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,1,4 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 33142-25:
(7*3)+(6*3)+(5*1)+(4*4)+(3*2)+(2*2)+(1*5)=75
75 % 10 = 5
So 33142-25-5 is a valid CAS Registry Number.

33142-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name diethyl α-formylmalonate

1.2 Other means of identification

Product number -
Other names DIETHYL A-FORMYLMALONATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33142-25-5 SDS

33142-25-5Relevant academic research and scientific papers

Reactions of α-chloro β-oxo aldehydes with CH-acid anions

Guseinov, F. I.

, p. 743 - 745 (2007/10/03)

The reactions of α-chloro and α,α-dichloro β-oxo aldehydes with carbanions are accompanied by the cleavage of the carbon-carbon bond in the chloro aldehydes and result in formylation of CH-acids. These electrophiles react with carbanions, which are generated in situ from CH-acids in the presence of AcONa in aprotic solvents, to form polyfunctional hydroxy compounds.

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