34102-91-5

Upstream product

• 108-86-1 bromobenzene 
• 627-63-4 fumaryl dichloride 
• 6332-09-8 1.4-bis-(4-bromo-phenyl)-butene-(2c)-dione-(1.4) 
• 1777-57-7 p-bromobenzoylmethylenetriphenylphosphorane 
• 36710-35-7 2,5-bis(4-bromophenyl)furan 
• 99-90-1 para-bromoacetophenone 
• 99-73-0 para-bromophenacyl bromide 
• 64-19-7 acetic acid 
• 67-66-3 chloroform 
• 7553-56-2 iodine 
• 7647-01-0 hydrogenchloride 
• 7446-08-4 selenium(IV) oxide 
• 64-17-5 ethanol 
• 2461-83-8 1,4-bis(4-bromophenyl)-1,4-butanedione 

Downstream Products

• 2461-83-8 1,4-bis(4-bromophenyl)-1,4-butanedione 
• 6332-09-8 1.4-bis-(4-bromo-phenyl)-butene-(2c)-dione-(1.4) 
• 74322-75-1 [6-(4-Bromo-benzoyl)-2-diethylamino-cyclohex-3-enyl]-(4-bromo-phenyl)-methanone 
• 165287-54-7 2,3-dibromo-1,4-bis-(4-bromo-phenyl)-butane-1,4-dione 
• 36710-35-7 2,5-bis(4-bromophenyl)furan 
• 107487-72-9 1-(4-Bromo-phenyl)-2-[3-(4-bromo-phenyl)-1,2-dihydro-quinoxalin-2-yl]-ethanone 
• 173420-64-9 1,4-bis-(4-bromo-phenyl)-2-methoxy-butane-1,4-dione 

Relevant academic research and scientific papers

Visible-Light-Driven Stereoselective Annulation of Alkyl Anilines and Dibenzoylethylenes via Electron Donor-Acceptor Complexes

A catalyst-free, stereoselective visible-light-driven annulation reaction between alkenes and N,N-substituted dialkyl anilines for the synthesis of substituted tetrahydroquinolines is presented. The reaction is driven by the photoexcitation of an electron donor-acceptor (EDA) complex, and the resulting products are obtained in good to high yields with complete diastereoselectivity. Mechanistic rationale and photochemical characterization of the EDA-complex are provided.

Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum

Malaria is one of the most significant tropical diseases and remains a major challenge due to the lack of a broadly effective vaccine and parasite resistance to current drugs. This means there is a need for new drug candidates with novel modes of action.

Asymmetric organocatalytic aza-michael reactions of isatin derivatives

Isatin was activated by derivatization to a Schiff base with aniline and used as an aza-Michael donor in organocatalytic asymmetric reactions with symmetric and nonsymmetric unsaturated 1,4-diketones. After hydrolysis (in situ), the N-substituted isatins were obtained in high yields (up to >95%) with high enantioselectivity (up to 95%).

Asymmetric diastereoselective synthesis of spirocyclopropane derivatives of oxindole

A new asymmetric organocatalytic synthesis of spirocyclopropane oxindoles has been developed. The method is based on the Michael addition of N-Boc-protected 3-chlorooxindole to unsaturated 1,4-dicarbonyl compounds, affording trans-substituted spirocyclopropane oxindole derivatives in high diastereo- and enantioselectivity. Copyright

Synthesis of (E)-1,4-enediones from α-halo ketones through a sodium sulfinate mediated reaction

We developed a mild and practical protocol for the synthesis of 1,4-enedione from α-halo ketones through a sodium sulfinate mediated reaction. This reaction enables the construction of symmetric and unsymmetric 1,4-enedione with complete E selectivity. Sodium 4-toluenesulfinate plays an important role in this reaction.

Lewis acid-catalyzed one-pot, three-component route to chiral 3,3′-bipyrroles

(Chemical Equation Presented) 3,3′-Bipyrroles 3 could be synthesized using a double Michael addition reaction involving diaroyl acetylene 1 and the appropriate 1,3-dicarbonyls 2 using ammonium acetate as a nitrogen source. The axial chirality of bipyrrole was anticipated from the X-ray crystal structure and DFT calculations and confirmed by separating the racemates on a chiral column and subsequent CD spectra of the enantiomers. The absolute configuration of the enantiomers was achieved by theoretical CD spectra calculation using the ZINDO method.

Reaction of N-fluoropyridinium salts with Wittig reagents: A novel and convenient approach to symmetric trans-olefins

N-Fluoropyridinium salts were found to react with Wittig reagents containing electron-withdrawing groups to give olefins in 47-83% yield. The mechanism of this conversion is believed in involve single-electron transfer from Wittig reagent to N-fluoropyridinium cation.