3587-84-6

Upstream product

• 96-09-3 styrene oxide 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 1674-30-2 1-phenyl-2-chloroethanol 
• 100-42-5 styrene 
• 100-52-7 benzaldehyde 
• 107-30-2 chloromethyl methyl ether 
• 27490-32-0 tributyl(methoxymethyl)stannane 
• 93-56-1 phenylethane 1,2-diol 
• 7664-93-9 sulfuric acid 
• 57308-70-0 2-iodo-1-phenylethan-1-ol 
• 124-38-9 carbon dioxide 
• 495-40-9 propiophenone 
• 4079-52-1 methoxymethyl phenyl ketone 

Downstream Products

• 91970-57-9 (+/-)-2-methoxy-1-(phenyl)ethyl acetate 
• 104-62-1 formic acid phenethyl ester 
• 60-12-8 2-phenylethanol 
• 29610-84-2 (1‐bromo‐2‐methoxyethyl)benzene 
• 4079-52-1 methoxymethyl phenyl ketone 
• 65-85-0 benzoic acid 
• 67-56-1 methanol 
• 98-86-2 acetophenone 
• 1457952-41-8 bis(2-methoxy-1-phenylethyl) carbonate 
• 1457952-40-7 2-methoxy-1-phenylethyl(2-methoxy-2-phenylethyl) carbonate 
• 1457952-37-2 2-methoxy-1-phenylethyl-1 H-imidazole-1-carboxylate 
• 1402465-55-7 1-(4'-(5-((2-methoxy-1-phenylethoxy)carbonylamino)-1-methyl-1H-pyrazol-4-yl)biphenyl-4-yl)cyclopropane-1-carboxylic acid 
• 1402466-13-0 ethyl 1-(4'-(5-(((2-methoxy-1-phenylethoxy)carbonyl)amino)-1-methyl-1H-pyrazol-4-yl)-[1,1 '-biphenyl]-4-yl)cyclopropanecarboxylate 

Relevant academic research and scientific papers

A NEW AND SIMPLE SYNTHESIS OF ALKOXY- AND ARYLOXYMETHYLLITHIUM REAGENTS (ROCH2Li)

A series of halomethyl alkyl and aryl ethers can be converted to the corresponding organolithium reagents (ROCH2Li) in a one-flask operation by sequential treatment (1) with stannous chloride-lithium bromide complex in tetrahydrofuran (THF) and (2) with n-butyllithium.

Tandem Acid/Pd-Catalyzed Reductive Rearrangement of Glycol Derivatives

Herein, we describe the acid/Pd-tandem-catalyzed transformation of glycol derivatives into terminal formic esters. Mechanistic investigations show that the substrate undergoes rearrangement to an aldehyde under [1,2] hydrogen migration and cleavage of an oxygen-based leaving group. The leaving group is trapped as its formic ester, and the aldehyde is reduced and subsequently esterified to a formate. Whereas the rearrangement to the aldehyde is catalyzed by sulfonic acids, the reduction step requires a unique catalyst system comprising a PdII or Pd0 precursor in loadings as low as 0.75 mol % and α,α′-bis(di-tert-butylphosphino)-o-xylene as ligand. The reduction step makes use of formic acid as an easy-to-handle transfer reductant. The substrate scope of the transformation encompasses both aromatic and aliphatic substrates and a variety of leaving groups.

Enantiopure encaged Verkade's superbases: Synthesis, chiroptical properties, and use as chiral derivatizing agent

Verkade's superbases, entrapped in the cavity of enantiopure hemicryptophane cages, have been synthesized with enantiomeric excess (ee) superior to 98%. Their absolute configuration has been determined by using electronic circular dichroism (ECD) spectros

PYRIDAZINONES AND METHODS OF USE THEREOF

Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).

Microporous Nanotubes and Nanospheres with Iron-Catechol Sites: Efficient Lewis Acid Catalyst and Support for Ag Nanoparticles in CO2 Fixation Reaction

FeIII-containing hyper-crosslinked microporous nanotubes (FeNTs) and nanospheres (FeNSs) are synthesized through the reaction of catechol and dimethoxymethane in the presence of FeCl3 or CF3SO3H. Both FeNTs and FeNSs demonstrate excellent catalytic activity in Lewis acid catalysis (hydrolysis and regioselective methanolysis of styrene oxide) and tandem catalysis involving a sequential oxidation-cyclization process, which selectively converts benzyl alcohol to 2-phenyl benzimidazole. Apart from Lewis acidity, the FeNTs and FeNSs also showed CO2 uptake capacities of 2.6 and 2.2 mmol g?1, respectively, at a pressure of 1 atm and temperature of 273 K. Furthermore, Ag nanoparticles are immobilized successfully on the surfaces of FeNTs and FeNSs by the liquid-phase impregnation method to prepare Ag@FeNT and Ag@FeNS nanocomposites, which show high catalytic activity for the selective fixation of CO2 to phenylacetylene to yield phenylpropiolic acid at 60 °C and 1 atm CO2 pressure. Hence, FeIII-catechol-containing hyper-crosslinked nanotubes and nanospheres have huge potential not only as Lewis acid catalysts, but also as excellent supports for immobilizing Ag nanoparticles in the design of a robust catalyst for the carboxylation of terminal alkynes, which has wide scope in catalysis and environmental research.

Aerobic Photooxidative Synthesis of β-Alkoxy Monohydroperoxides Using an Organo Photoredox Catalyst Controlled by a Base

Transition-metal-free synthesis of β-alkoxy monohydroperoxides via aerobic photooxidation using an acridinium photocatalyst was developed. This method enables the synthesis of some novel hydroperoxides. The peroxide source is molecular oxygen, which is cost-effective and atomically efficient. Magnesium oxide plays an important role as a base in the catalytic system.

Ru(III) complex anchored onto amino-functionalized MIL-101(Cr) framework via post-synthetic modification: an efficient heterogeneous catalyst for ring opening of epoxides

In this work, the metallo Schiff base-functionalized metal–organic framework was prepared by post-synthetic method and used as an electron-deficient catalyst for the alcoholysis of epoxides. In this manner, the aminated MIL-101 was modified with 2-pyridine carboxaldehyde and then the prepared Schiff base reacted with RuCl3. This new catalyst, MIL-101–NH2–PC–Ru, was characterized by Fourier transform infrared, UV–Vis spectroscopic techniques, X-ray diffraction, BET, inductively coupled plasma atomic emission spectroscopy and field-emission scanning electron microscopy. In the presence of this heterogeneous catalyst, ring opening of epoxides was performed under mild condition to show the significant ability and successful applications of Lewis acid containing catalysts in corporation with metal–organic frameworks. The reusability of the catalyst was also investigated. No noticeable decrease in the catalytic activity was found after four consecutive times.

Modular bisphosphine ligands: Preparation and application in enantioselective catalytic reactions

A set of six chiral modular C2-symmetric bisphosphine ligands have been synthesized in a straightforward manner through a two-step reaction from the corresponding diols with moderate yields. The applicability of these chiral ligands was evaluated in ruthenium(II)-catalyzed transfer hydrogenation reactions (up to >99% conversion) and palladium(0)-catalyzed enantioselective allylic substitution reactions (up to 70% chemical yield and 43% ee).

An Fe3O4 nanoparticle-supported Mn (II)-azo Schiff complex acts as a heterogeneous catalyst in alcoholysis of epoxides

In this paper, an azo-containing Schiff base complex of manganese [Mn2+-azo ligand@APTES-SiO2@Fe3O4] immobilized on chemically modified Fe3O4 nanoparticles has been used as a magnetically retrievable catalyst for the alcoholysis of different epoxides to their corresponding alkoxy alcohols with methanol, ethanol and n-propanol. The newly magnetic nanoparticles (MNPs) were characterized by Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX) and vibrating sample magnetometry (VSM).

Scalable and super-stable exfoliation of graphitic carbon nitride in biomass-derived γ-valerolactone: Enhanced catalytic activity for the alcoholysis and cycloaddition of epoxides with CO2

Biomass-derived γ-valerolactone (GVL) could exfoliate bulk g-C3N4 to form a super-stable dispersion of few-layer g-C3N4 nanosheets with a high concentration of up to 0.8 mg mL-1 due to the polarity and the appropriate surface energy of GVL. The exfoliation process can be easily extended to a 200 ml scale and should be extended further. The formed g-C3N4 nanosheets showed enhanced activity for the alcoholysis of epoxides and the cycloaddition of epoxides with CO2 owing to their higher specific surface areas and more exposed active centers than the bulk g-C3N4. This affords a green, facile and scalable method to form few-layer g-C3N4 nanosheets and further expand the application of g-C3N4 materials to the field of non-photocatalysis.