36727-29-4 Usage
Description
3,5,5-Trimethylhexanoyl chloride (isononanoyl chloride) may be used as a reagent in the synthesis of barbituric acid analogs, as a starting material in the synthesis of alpha-N-fatty acyl colistin nonapeptide derivative, and as a reactant in the synthesis of 3,5,5-trimethylhexanamide1. It is also an intermediate used in the manufacturing of organic peroxides, pharmaceuticals, crop protection agents, pesticides and dyes2.
Sources
https://www.sigmaaldrich.com/catalog/product/aldrich/422959?lang=en®ion=US
http://www.matweb.com/search/DataSheet.aspx?MatGUID=b05d4559acc04ebeaa22c1c5850e479a&ckck=1
Uses
3,5,5-Trimethylhexanoyl chloride (isononanoyl chloride) may be used:As a reagent in the synthesis of barbituric acid analogs As a starting material in the synthesis of α-N-fattyacyl colistin nonapeptide derivative.As a reactant in the synthesis of 3,5,5-trimethylhexanamide.
General Description
3,5,5-Trimethylhexanoyl chloride (isononanoyl chloride) is an acid chloride. Its has been reported to be synthesized by the chlorination of isononanoic acid with thionyl chloride.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 36727-29-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,7,2 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36727-29:
(7*3)+(6*6)+(5*7)+(4*2)+(3*7)+(2*2)+(1*9)=134
134 % 10 = 4
So 36727-29-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H17ClO/c1-7(5-8(10)11)6-9(2,3)4/h7H,5-6H2,1-4H3
36727-29-4Relevant articles and documents
Method for realizing continuous production of acyl chloride compound through immobilization of organic base catalyst
-
Paragraph 0051-0059, (2021/08/14)
The invention discloses a method for realizing continuous production of an acyl chloride compound through immobilization of an organic base catalyst, and belongs to the technical field of organic chemical industry. Amino, pyridine, acetamide and nicotinamide organic base silane coupling agents are used for treating a glass micro-channel reactor to immobilize an organic base catalyst; by taking 3, 5, 5-trimethyl hexanoic acid, adipic acid, trimethyl acetic acid, benzoic acid and terephthalic acid as raw materials, acylating chlorination reaction is carried out through a fixed bed micro-channel to generate corresponding 3, 5, 5-trimethyl hexanoyl chloride, adipoyl chloride, trimethyl acetyl chloride, benzoyl chloride and terephthaloyl chloride; the solvent(s) is/are one or more of methylbenzene, dichloromethane, dichloroethane, cyclohexane and tetrahydrofuran; the molar ratio of the carboxylic acid groups to the triphosgene is 3: (1-1.5); and the reaction temperature is 30-150 DEG C, the total feeding speed of the materials is 5-40 mL/min, and the reaction time is 2-16 min. The 3, 5, 5-trimethyl hexanoyl chloride, benzoyl chloride and adipoyl chloride are produced by the method disclosed by the invention, the repeated utilization of the catalyst is realized, the product purity is high, the production process is safe, and the environmental pollution is reduced.