39561-82-5

Basic information

• Product Name: 2-(4-Chlorophenyl)-2-oxoethyl acetate
• Synonyms: 2-(4-Chlorophenyl)-2-oxoethyl acetate;2-(acetyloxy)-1-(4-chlorophenyl)ethanone
• CAS NO: 39561-82-5
• Molecular Formula: C₁₀H₉ClO₃
• Molecular Weight: 212.62966
• Mol File: 39561-82-5.mol
• Article Data: 19

Chemical Properties

• Melting Point: 174-176°
• Boiling Point: 319.4°C at 760 mmHg
• Flash Point: 137.1°C
• Appearance: /
• Density: 1.255g/cm³
• Vapor Pressure: 0.00034mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: 2-(4-Chlorophenyl)-2-oxoethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chlorophenyl)-2-oxoethyl acetate(39561-82-5)
• EPA Substance Registry System: 2-(4-Chlorophenyl)-2-oxoethyl acetate(39561-82-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 39561-82-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 6, p. 59, 1976 DOI: 10.1080/00397917608062134

InChI:InChI=1/C10H9ClO3/c1-7(12)14-6-10(13)8-2-4-9(11)5-3-8/h2-5H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 58518-76-6 ((1-(4-chlorophenyl)vinyl)oxy)trimethylsilane 
• 108-24-7 acetic anhydride 
• 99-91-2 para-chloroacetophenone 
• 3240-10-6 (4-chlorophenyl)propiolic acid 
• 873-73-4 4-n-chlorophenylacetylene 
• 127-08-2 potassium acetate 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 208118-80-3 1-(4-chlorophenyl)ethenylacetamide 
• 637-87-6 1-Chloro-4-iodobenzene 
• 13831-31-7 Acetoxyacetyl chloride 
• 77295-59-1 1-chloro-4-(2,2-dibromovinyl)benzene 
• 64-19-7 acetic acid 
• 937-20-2 p-chlorophenacyl chloride 

Downstream Products

• 83081-17-8 2-(4-Chlorphenyl)-4-ethylmorpholin 
• 27993-56-2 1-(4-chlorophenyl)-2-hydroxyethanone 
• 7477-64-7 (S)-1-(4-chlorophenyl)-1,2-ethanediol 
• 152142-03-5 (1R)-1-(4-chlorophenyl)-1,2-ethanediol 
• 83081-14-5 2-(4-Chloro-phenyl)-4-methyl-morpholine 

Relevant articles and documents

Decarboxylative Oxyacyloxylation of Propiolic Acids: Construction of Alkynyl-Containing α-Acyloxy Ketones

Novel decarboxylative oxyacyloxylation of propiolic acids has been developed. This reaction provides an efficient access to alkynyl-containing α-acyloxy ketones from readily available starting materials and exhibits significant functional group tolerance. Furthermore, oxyacyloxylation of terminal alkynes and aliphatic propiolic acids was also developed. A possible reaction mechanism is proposed based on mechanistic studies.

Oxidative α-Acetoxylation of a β-Oxime Ester with (Diacetoxyiodo)benzene Catalyzed by ScIII Salts: An Approach to the Docetaxel Side Chain

Hypervalent iodine(III) compounds have emerged as reagents of choice for α-oxidation of various ketones under mild reaction conditions. We report herein a simple method for α-hydroxylation of a β-oxime ester, which involves an oxidative α-acetoxylation us

Novel and efficient transformation of enamides into α-acyloxy ketones via an acyl intramolecular migration process

Hydrogen peroxide and anhydride mediated transformation of enamides to afford substituted α-acyloxy ketones is described. This transition-metal-free cascade reaction has a broad substrate scope and high efficiency. The acyl intramolecular migration procedure successfully achieved this acyloxylation process under mild conditions and increased the atom efficiency.