479-20-9 Usage
Description
Atranorin is a depside lichen metabolite that has been found in S. alpinum and exhibits diverse biological activities. It possesses potent antimicrobial, anti-inflammatory, and antinociceptive properties, along with potential anticancer capabilities. Atranorin is a derivative compound of Chloratranorin (C364120), which are metabolites of Evernia prunastri, and it also functions as an antioxidant.
Used in Pharmaceutical Applications:
Atranorin is used as an antimicrobial agent for its activity against various bacteria, including B. cereus, B. subtilis, S. aureus, S. faecalis, P. vulgaris, L. monocytogenes, and A. hydrophila. It also shows effectiveness against fungi such as C. albicans and C. glabrata, as well as the mycobacterium M. aurum.
Atranorin is used as an antinociceptive agent for its ability to inhibit acetic acid-induced writhing in mice when administered orally at doses of 200 and 400 mg/kg.
Atranorin is used as an anti-inflammatory agent for its effectiveness in reducing paw licking and biting in the second phase of the formalin test when administered 30 minutes prior to formalin in mice.
Used in Cosmetic Applications:
Atranorin is used as a component in extracts of oak moss, which are utilized as a fragrance in the cosmetic industry.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, Atranorin's cytotoxicity to certain cancer cells (A270, HL-60, and Jurkat) suggests potential use as an anticancer agent. Further research would be required to explore this application fully.
Used in Antioxidant Applications:
Atranorin functions as an antioxidant, which could have various applications in different industries, such as pharmaceuticals, cosmetics, and the food industry, to protect against oxidative stress and maintain product stability.
Hazard
A poison by skin contact. A skin irritant.
Safety Profile
A poison by skin
contact. A skin irritant. When heated to
decomposition it emits acrid smoke and
irritating vapors.
Check Digit Verification of cas no
The CAS Registry Mumber 479-20-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 479-20:
(5*4)+(4*7)+(3*9)+(2*2)+(1*0)=79
79 % 10 = 9
So 479-20-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H18O8/c1-8-5-12(21)11(7-20)17(23)15(8)19(25)27-13-6-9(2)14(18(24)26-4)16(22)10(13)3/h5-7,21-23H,1-4H3