5066-65-9

Basic information

• Product Name: 3-(2-FURYL)-1-(4-METHOXYPHENYL)PROP-2-EN-1-ONE
• Synonyms: 3-(2-FURYL)-1-(4-METHOXYPHENYL)PROP-2-EN-1-ONE
• CAS NO: 5066-65-9
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24
• Mol File: 5066-65-9.mol
• Article Data: 41

Chemical Properties

• Boiling Point: 371.2°C at 760 mmHg
• Flash Point: 178.3°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 1.05E-05mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: 3-(2-FURYL)-1-(4-METHOXYPHENYL)PROP-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-FURYL)-1-(4-METHOXYPHENYL)PROP-2-EN-1-ONE(5066-65-9)
• EPA Substance Registry System: 3-(2-FURYL)-1-(4-METHOXYPHENYL)PROP-2-EN-1-ONE(5066-65-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 5066-65-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H12O3/c1-16-12-6-4-11(5-7-12)14(15)9-8-13-3-2-10-17-13/h2-10H,1H3/b9-8+

Upstream product

• 98-01-1 furfural 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 20689-54-7 3-furanylacryloyl chloride 
• 100-66-3 methoxybenzene 
• 5031-78-7 4-phenoxyacetophenone 
• 13331-23-2 fur-2-ylboronic acid 
• 51410-44-7 1-(4-methoxylphenyl)-2-propen-1-ol 
• 98-03-3 thiophene-2-carbaldehyde 
• 20689-54-7 (E)-3-(2-furyl)acryloyl chloride 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 18708-18-4 furfural tosylhydrazone 
• 20912-79-2 4-methoxyphenacylidene dimethylsulphurane 

Downstream Products

• 77607-69-3 2-Amino-4-furan-2-yl-6-(4-methoxy-phenyl)-nicotinonitrile 
• 133617-60-4 3-cyano-4-(2-furyl)-6-(4-methoxyphenyl)-2-methylpyridine 
• 77607-75-1 4-Furan-2-yl-6-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 132808-73-2 6-Furan-2-yl-4-(4-methoxy-phenyl)-5,6-dihydro-1H-pyrimidine-2-thione 
• 114570-73-9 [(1R,2S,3R,4S)-2,3-Di-furan-2-yl-4-(4-methoxy-benzoyl)-cyclobutyl]-(4-methoxy-phenyl)-methanone 
• 114570-77-3 5-Methoxy-5-[(E)-3-(4-methoxy-phenyl)-3-oxo-propenyl]-5H-furan-2-one 
• 61833-77-0 (4-furan-2-yl-4,5-dihydro-1H-pyrazol-3-yl)-(4-methoxy-phenyl)-methanone 
• 109979-80-8 6-[2]furyl-4-(4-methoxy-phenyl)-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester 

Relevant articles and documents

Novel 4,5-dihydro-1H-pyrazole derivatives as potential succinate dehydrogenase inhibitors: design, synthesis, crystal structure, biological activity and molecular modeling

Twenty-eight new 4, 5-dihydro-1H-pyrazole derivatives were designed, synthesized and characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure of compound 2j was characterized by single crystal X-ray diffraction. Their ant

Alkene Synthesis by Photo-Wolff-Kischner Reaction of Sulfur Ylides and N-Tosylhydrazones

A visible-light-driven and room temperature photo-Wolff-Kischner reaction of sulfur ylides and N-tosylhydrazones has been developed for the first time to provide modular access to alkene synthesis. The high functional group tolerance and broad substrate scope were demonstrated by more than 60 examples. Both E- and Z-olefinic stereochemistry in the products could be controlled with excellent stereoselectivity. A series of mechanistic studies support that the reaction should proceed through a radical-carbanion crossover pathway, specifically involving addition of photo-generated sulfur ylide radical cations to N-tosylhydrazones to form carbanions and subsequent Wolff-Kischner process.

Copper-Promoted Oxidative Intramolecular C–H Amination of Hydrazones to Synthesize 1H-Indazoles and 1H-Pyrazoles Using a Cleavable Directing Group

A facile and efficient synthesis of 1H-indazoles and 1H-pyrazoles through a copper-promoted oxidative intramolecular C–H amination of hydrazones using a cleavable directing group was developed. This reaction is characterized by its mild conditions, operational simplicity, readily available reagents, and excellent yields. A tentative mechanism for Cu-mediated C–H oxidative amination was proposed.