599-64-4

Usage

Uses

Used in Plastic and Rubber Industries:
p-Cumylphenol is used as an intermediate for the production of antioxidants, stabilizers, and UV absorbers. Its presence in these additives helps to prevent the degradation of plastics and rubbers, thereby enhancing their durability and performance.
Used in Pharmaceutical Industry:
p-Cumylphenol serves as an intermediate in the production of pharmaceuticals. Its unique chemical structure contributes to the development of various medicinal compounds, making it an essential component in the pharmaceutical manufacturing process.
Used in Disinfectant Production:
Due to its antimicrobial properties, p-Cumylphenol is used as an intermediate in the production of disinfectants. It helps to eliminate harmful microorganisms, ensuring cleanliness and safety in various applications.
Used in Fragrance Industry:
p-Cumylphenol is employed as an intermediate in the production of fragrances. Its unique scent profile contributes to the creation of various fragrances used in personal care and cosmetic products.
Used in Personal Care and Cosmetic Products:
Leveraging its antimicrobial properties, p-Cumylphenol is used in personal care and cosmetic products to maintain cleanliness and prevent the growth of harmful microorganisms. It helps to ensure the safety and efficacy of these products.
However, it is important to note that prolonged or repeated exposure to p-Cumylphenol may cause skin or eye irritation. Therefore, proper safety measures should be taken when handling p-Cumylphenol.

InChI:InChI=1/C15H16O/c1-12(11-13-5-3-2-4-6-13)14-7-9-15(16)10-8-14/h2-10,12,16H,11H2,1H3

Upstream product

• 98-82-8 Isopropylbenzene 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 80-15-9 Cumene hydroperoxide 
• 6623-93-4 1-(2-(4-methoxyphenyl)propan-2-yl)benzene 
• 98-83-9 isopropenylbenzene 
• 108-95-2 phenol 
• 934-53-2 cumenyl chloride 
• 1940-95-0 1-ethoxy-4-(2-phenylpropan-2-yl)benzene 
• 20056-52-4 tri-4-(2-phenylisopropyl)phenyl phosphate 
• 7446-70-0 aluminium trichloride 
• 10035-10-6 hydrogen bromide 
• 52820-06-1 toluene-2,4-di(carbamic acid (4-cumylphenyl) ester) 
• 103-73-1 Phenetole 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 3692-16-8 4-(1-methyl-1-phenyl-ethyl)-2,6-bis-piperidinomethyl-phenol 
• 116281-64-2 2,6-bis-[2-hydroxy-5-(1-methyl-1-phenyl-ethyl)-benzyl]-4-methyl-phenol 
• 24133-64-0 4-(1-methyl-1-phenyl-ethyl)-2-nitro-phenol 
• 22223-51-4 2,6-dichloro-4-(1-methyl-1-phenyl-ethyl)-phenol 
• 52891-47-1 β-Phenyl-p-cumenylphosphorodichloridate 
• 70757-61-8 [4-(1-methyl-1-phenyl-ethyl)-phenoxy]-acetic acid 
• 50807-15-3 4-(2-cyclohexylpropan-2-yl)cyclohexanol 
• 20056-52-4 tri-4-(2-phenylisopropyl)phenyl phosphate 
• 91133-59-4 3-methyl-3-phenyl-2-oxobutanoic acid 
• 6623-93-4 1-(2-(4-methoxyphenyl)propan-2-yl)benzene 
• 56949-68-9 1-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-propan-2-ol 
• 59426-97-0 Butane-2-sulfonic acid 4-(1-methyl-1-phenyl-ethyl)-phenyl ester 
• 64523-66-6 1-Diphenoxymethoxy-4-(1-methyl-1-phenyl-ethyl)-benzene 
• 64523-87-1 C₃₇H₃₆O₃ 

Relevant academic research and scientific papers

MULTISTEP PROCESS FOR THE PREPARATION OF HEXAMETHYLENE DIISOCYANATE, PENTAMETHYLENE DIISOCYANATE OR TOLUENE DIISOCYANATE

The present invention relates to a multistep process for the preparation of organic diisocyanates by converting the corresponding diamine precursors, urea and hydroxy compounds into monomeric diurethanes, converting these diurethanes into diurethanes of high boiling hydroxy compounds, and finally cleavage of the latter diurethanes to form the diisocyanates and recover the high boiling hydroxy compounds.

Catalytic Hydroarylation of Alkenes with Phenols using B(C6F5)3

We demonstrate that tris(pentafluorophenyl)borane, B(C6F5)3, is shown to be an effective catalyst for the hydroarylation of olefins to yield substituted phenols. This system features fast reaction times, mild conditions, and good yields for a select scope of olefinic substrates and various phenols, resulting in C-C bond formation. Experimental data support two possible mechanisms, where the Lewis acid can activate either the olefin or the phenol as the first step in the catalytic mechanism.

METHOD FOR MANUFACTURING α-METHYLSTYRENATED PHENOL

According to an embodiment of the present invention, the present invention provides a method for manufacturing α-methyl styrenated phenol, which comprises the following steps: (a) making phenol react with α-methyl styrene (AMS) under the presence of a first acidic catalyst to obtain a first product; and (b) additionally making 1-5 equivalents of α-methyl styrene for 1 equivalent of phenol react with the first product under the presence of a second acidic catalyst to obtain a second product. The manufactured α-methyl styrenated phenol does not generate environmental damage and is economical.(a) Making phenol react with α-methyl styrene (AMS) under the presence of a first acidic catalyst(AA) Obtaining 30-50 wt% of TMPI, 1-10 wt% DMP, 5-20 wt% of cumyl phenol, 1-10 wt% of AMS trimer, and the remaining phenol(b) Additionally making the α-methyl styrene react with a first product under the presence of a second acidic catalyst(BB) Obtaining 5-50 wt% of TMPI + DMP, 2-20 wt% of cumyl phenol, 1-10 wt% of dicumene, 20-60 wt% of dicumyl phenol, and 0.1-5 wt% of AMS trimerCOPYRIGHT KIPO 2017

Phenylethyl/heteroploid c phenyl phenol preparation method of compound (by machine translation)

The invention relates to phenyl-based/heteroploid c phenyl phenol preparation method of the compound. The technical scheme is:to styrenic compound and a phenol compound as a raw material, to solid acid H 2 SO 4-SiO 2 as a catalyst, prepared by Friedel-crafts alkylation reaction. The method of the present invention the reaction temperature is low, the reaction speed is fast, the liquid acid to the product solution is caused by the oxidization reaction complex, difficulties and later processing is caused by the problem of serious corrosion of the equipment. (by machine translation)

Calcium-catalyzed hydroarylation of alkenes at room temperature

Calcium-catalyst gaining ground: A variety of electron-poor electron-rich and trisubstituted styrene derivatives were reacted to give the desired diarylalkanes within less than an hour at room temperature in the presence of 2.5 mol % of Ca(NTf2)2/Bu4NPF6 (see scheme). Additionally the highly reactive calcium catalyst was successfully applied for the hydroarylation of dienes and even trisubstituted olefins.

Rhenium-catalyzed regioselective alkylation of phenols

(Chemical Equation Presented) Treatment of phenol derivatives with terminal alkenes in the presence of a catalytic amount of a rhenium complex, Re 2(CO)10, gave monoalkylated phenol derivatives in good to excellent yields. This reaction proceeds at the ortho- or para-position of phenols regioselectively.

Synthesis of 4-tert-octylphenol and 4-cumylphenol by metal triflate and metal triflimidate catalysts

Metal inflates and metal triflimidates are shown to catalyse efficiently the Friedel-Crafts alkylation of phenol with alkenes. Bismuth, copper and scandium triflates lead to very good yields with excellent para-selectivities.

A traceless perfluoroalkylsulfonyl (PFS) linker for the deoxygenation of phenols

(Equation presented) The synthesis of a novel perfluoroalkylsulfonyl (PFS) fluoride is described for use as a traceless linker in solid-phase organic synthesis. Attachment to the resin and subsequent coupling of a phenol affords a stable arylsulfonate that behaves as a support-bound aryl triflate. Palladium-mediated reductive cleavage of a wide variety of phenols generated the parent arenes. The resin-bound aryl triflate was shown to be stable to reductive amination conditions, and the traceless synthesis of Meclizine is reported.

Electrophilic Aromatic Alkylation by Hydroperoxides. Competition between Ionic and Radical Mechanisms with Phenols

Tertiary hydroperoxides have been utilized for the electrophilic alkylation of activated aromatic substrates, particularly phenols and phenol ethers. Cumyl (1) and tert-butyl (2) hydroperoxides have shown a greatly different behavior as concerns the catalysis and the regioselectivity. The best catalyst for 1 is TiCl4, which is completely inactive with 2. With the latter an effective catalyst is FeCl3, which, however, can give rise to a combination of electrophilic and radical reactions with alkyl phenols. 2,2′-Dihydroxy-3,3′-di-tert-butyl-5,5′-dimethyldiphenyl is obtained in high yields from p-cresol.