616-07-9

Basic information

• Product Name: DL-ornithine
• Synonyms: Ornithine,DL-;rac-(2R*)-2,5-Diaminopentanoic acid;2,5-bis(azanyl)pentanoic acid;DL-Ornithine 50% aqueous solution
• CAS NO: 616-07-9
• Molecular Formula: C₅H₁₂N₂O₂
• Molecular Weight: 132.16098
• EINECS: 210-463-2
• Mol File: 616-07-9.mol
• Article Data: 26

Chemical Properties

• Melting Point: 232 °C
• Boiling Point: 308.7oC at 760 mmHg
• Flash Point: 140.5oC
• Appearance: /
• Density: 1.165g/cm3
• Vapor Pressure: 0.00015mmHg at 25°C
• Refractive Index: 1.507
• PKA: 2.45±0.24(Predicted)
• CAS DataBase Reference: DL-ornithine(CAS DataBase Reference)
• NIST Chemistry Reference: DL-ornithine(616-07-9)
• EPA Substance Registry System: DL-ornithine(616-07-9)

Safety Data

• Hazardous Substances Data: 616-07-9(Hazardous Substances Data)

Usage

General Description

DL-ornithine is a naturally occurring amino acid that is important for the urea cycle, which is responsible for the removal of ammonia from the body. It is often used as a dietary supplement to promote muscle growth, enhance athletic performance, and improve overall health. DL-ornithine is also thought to have potential benefits for reducing fatigue, supporting liver health, and promoting wound healing. It is considered generally safe and well-tolerated, but excessive intake may cause gastrointestinal side effects. Overall, DL-ornithine plays a crucial role in various physiological functions and may offer several potential health benefits as a supplement.

InChI:InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)

Upstream product

• 542-32-5 (R,S)-2-aminoadipic acid 
• 7438-77-9 Orn-δ-NOH 
• 7647-01-0 hydrogenchloride 
• 4405-04-3 PTH-Arginine 
• 65406-11-3 N²,N⁵-bis-phenylacetyl-ornithine 
• 132465-72-6 N²-(toluene-4-sulfonyl)-D-glutamine methyl ester 
• 42749-49-5 N²-(toluene-4-sulfonyl)-D-glutamine 
• 100616-51-1 N-(toluene-4-sulfonyl)-D-glutamic acid-1-methyl ester-5-nitrile 
• 69980-44-5 N⁵-benzoyl-DL-ornithine 
• 145876-67-1 N²,N⁵-bis-(furan-2-carbonyl)-ornithine 
• 74-79-3 L-arginine 
• 7200-25-1 Arg 
• 70-26-8 L-ornithine 
• 1119-34-2 L-arginine hydrochloride 

Downstream Products

• 5058-01-5 3-hydroxytetrahydro-2H-pyran-2-one 
• 2000-59-1 5-amino-2-oxo-valeric acid 
• 110-60-1 1,4-diaminobutane 
• 74-79-3 L-arginine 
• 70-26-8 2,5-diaminopentanoic acid 
• 5724-81-2 1-pyrroline 
• 113737-73-8 D-Ornithyl-L-methionyl-L-aspartyl-L-phenylalanine amide hydrochloride 
• 439152-10-0 N²,N⁵-bis(2,3-diacetoxybenzoyl)-D-ornithine 
• 2274-58-0 N,N'-di(benzyloxycarbonyl)-D-ornithine 
• 95610-96-1 (5S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3,8,14-trioxo-1,4,9-triaza-cyclotetradecane-5-carboxylic acid amide 
• 106732-42-7 (2S,5S,12R,15S,18S,25R)-12,25-Bis-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-2,15-dibenzyl-3,7,13,16,20,26-hexaoxo-1,4,8,14,17,21-hexaaza-cyclohexacosane-5,18-dicarboxylic acid diamide 
• 96382-72-8 H-Tyr-D-Orn[*]-Phe-Asp[*]-NH2 
• 97974-52-2 (2S,5S,12R)-12-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-isobutyl-3,7,13-trioxo-1,4,8-triaza-cyclotridecane-5-carboxylic acid amide 
• 2640-58-6 N²-benzyloxycarbonyl-L-ornithine 

Relevant articles and documents

Catenulobactins A and B, Heterocyclic Peptides from Culturing Catenuloplanes sp. with a Mycolic Acid-Containing Bacterium

The production of two new heterocyclic peptide isomers, catenulobactins A (1) and B (2), in cultures of Catenuloplanes sp. RD067331 was significantly increased when it was cocultured with a mycolic acid-containing bacterium. The planar structures and absolute configurations of the catenulobactins were determined based on NMR/MS and chiral-phase GC-MS analyses. Catenulobactin B (2) displayed Fe(III)-chelating activity and moderate cytotoxicity against P388 murine leukemia cells.

FUNCTIONALIZED FLUORINE CONTAINING PHTHALOCYANINE MOLECULES

Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.

Lysine racemase from a lactic acid bacterium, Oenococcus oeni: Structural basis of substrate specificity

Oenococcus oeni, a lactic acid bacterium, possesses a lysine racemase, which has a specific activity towards basic amino acids. A comparison of amino acid residues around the active site suggested that Ile222 and Tyr354 of the Geobacillus stearothermophilus alanine racemase, which shares 60% sequence similarity with lysine racemase, were replaced by Thr224 and Trp355 in the O. oeni lysine racemase. T224I/W355Y double mutations significantly decreased the activity of lysine racemase, whereas I222T/Y354W double mutations endowed alanine racemase with lysine racemization activity. These results suggest that the two residues play an important role in lysine racemization.