63096-36-6

Basic information

• Product Name: (4-chloro-phenyl)-hydroxy-acetic acid methyl ester
• Synonyms: (4-chloro-phenyl)-hydroxy-acetic acid methyl ester
• CAS NO: 63096-36-6
• Molecular Weight: 200.622
• Mol File: 63096-36-6.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: (4-chloro-phenyl)-hydroxy-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chloro-phenyl)-hydroxy-acetic acid methyl ester(63096-36-6)
• EPA Substance Registry System: (4-chloro-phenyl)-hydroxy-acetic acid methyl ester(63096-36-6)

Safety Data

• Hazardous Substances Data: 63096-36-6(Hazardous Substances Data)

Usage

General Description

The chemical compound (4-chloro-phenyl)-hydroxy-acetic acid methyl ester, also known as 4-chloro-α-methylphenylacetic acid methyl ester, is an organic compound with the molecular formula C9H9ClO3. It is a methyl ester of (4-chloro-phenyl)-hydroxyacetic acid and is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various medications. (4-chloro-phenyl)-hydroxy-acetic acid methyl ester has a phenyl and chloro substituent along with a hydroxy-acetic acid functional group, making it a versatile building block for the synthesis of a wide range of pharmaceuticals and fine chemicals. It is important to handle and store this compound with care, as it can be hazardous if not properly handled.

Upstream product

• 52449-43-1 (4-chloro-phenyl)-acetic acid methyl ester 
• 7138-34-3 p-chloromandelic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1504663-21-1 [4-chlorophenyl(dimethylphenylsilyl)methoxy]trimethylsilane 
• 1353044-28-6 (4-chlorophenyl)[dimethyl(phenyl)silyl]methanol 
• 67-56-1 methanol 
• 4998-15-6 4-chlorophenylglyoxal 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 99-91-2 para-chloroacetophenone 
• 93961-29-6 methyl 2-(4-chlorophenyl)-2-diazoacetate 
• 37542-28-2 methyl (p-chlorphenyl)glyoxylate 
• 76496-63-4 (S)-4-chloro-α-hydroxy-benzeneacetic acid 
• 144758-63-4 Butyric acid (4-chloro-phenyl)-methoxycarbonyl-methyl ester 
• 32174-34-8 methyl 4-chloromandelate 

Downstream Products

• 37542-28-2 methyl (p-chlorphenyl)glyoxylate 
• 18584-27-5 2-(4-chlorophenyl)-2-hydroxyacetamide 
• 492-86-4 (R)-4-chloro-α-hydroxy-benzeneacetic acid 
• 186025-92-3 methyl 4-chloro-α-(methanesulfonyloxy)phenylacetate 
• 947590-61-6 C₂₃H₂₃ClN₂O₅S 
• 1260146-56-2 1-hydroxy-1-(4-chlorophenyl)-3-phenylpropanone 
• 1260146-94-8 C₁₆H₂₆ClNO₃Si 
• 854676-79-2 1-hydroxy-1-(4-chlorophenyl)-3-phenylpropanone 
• 1260146-93-7 2-(4-chlorophenyl)-2-hydroxy-N-methoxy-N-methylacetamide 
• 1584127-67-2 (S)-(+)-methyl 2-acetoxy-2-(4-chlorophenyl)acetate 
• 32174-34-8 (4-chloro-phenyl)-hydroxy-acetic acid methyl ester 
• 4674-24-2 2-(4-chlorophenyl)-2-methoxyacetic acid 
• 23953-39-1 (2R)-2-(4-chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]acetic acid 
• 13312-93-1 4-chloro-α-hydroxyphenylacetyl hydrazine 

Relevant articles and documents

Direct Aerobic α-Hydroxylation of Arylacetates for the Synthesis of Mandelates

Aerobic α-hydroxylation of α-methylene esters has proven challenging due to overoxidation and hydrolysis of the materials. In this article, KOtBu-promoted TBAB-catalyzed α-hydroxylation of α-methylene aryl esters using O2as the oxyge

Cobalt-Catalyzed Transfer Hydrogenation of α-Ketoesters and N-Cyclicsulfonylimides Using H2O as Hydrogen Source

A Co-catalyzed effective transfer hydrogenation of various α-ketoesters and N-cyclicsulfonylimides by safe and environmentally benign H2O as hydrogen source is described. The reaction used easily available and easy to handle zinc metal as a reductant. Interestingly, the catalytic system does not require ligand for reduction of N-cyclicsulfonylimides. (Figure presented.).

A containing "1, 3, 4 - oxadiazole thioether" mandelic acid derivatives and use thereof

The invention discloses a containing "1, 3, 4 - oxadiazole thioether" mandelic acid derivatives and their use in the application of the fungi anti-plants sickness, the compound has the general formula (B) structure shown: In the formula, R1 Is H, methyl, fluorine or chlorine, R2 C for containing1 - 3 Straight-chain alkyl, containing C1 - 4 Branched alkyl, propenyl, propynyl or mono-substituted benzyl, wherein the single substituted benzyl substituent is "nitro, methyl, trifluoromethyl, methoxy, three methoxy, fluorine, and bromine". The invention to replace the mandelic acid as the skeleton, mandelic acid introduced in the structure of the "oxadiazole thioether" structure, design synthesizing a containing "1, 3, 4 - oxadiazole thioether" structure of the mandelic acid derivatives, anti-plant disease fungal activity tests show that the class of compounds of plant diseases caused by fungi has good inhibition activity, for the new pesticide research and development and create provide important scientific basis.