6937-97-9

Usage

Uses

Used in Pharmaceutical Synthesis:
[(prop-2-en-1-ylsulfanyl)methyl]benzene is used as a precursor in the pharmaceutical industry for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of pharmaceuticals, making it a valuable starting material in drug development.
Used in Pesticide Production:
In the agricultural sector, [(prop-2-en-1-ylsulfanyl)methyl]benzene serves as a starting material for the production of pesticides. Its chemical properties enable the development of effective compounds to protect crops from pests and diseases.
Used in Organic Compound Synthesis:
[(prop-2-en-1-ylsulfanyl)methyl]benzene is also utilized in the synthesis of other organic compounds across various industries. Its versatility as a building block allows for the creation of a broad spectrum of products, from specialty chemicals to advanced materials.
Safety Precautions:
Given its flammable nature and potential health hazards, [(prop-2-en-1-ylsulfanyl)methyl]benzene should be handled with care and in a well-ventilated area to ensure the safety of those working with it. Proper handling protocols and safety measures should be followed to minimize risks.

Upstream product

• 106-95-6 allyl bromide 
• 100-53-8 phenylmethanethiol 
• 3492-64-6 sodium benzylmercaptide 
• 107-05-1 3-chloroprop-1-ene 
• 102391-59-3 Allyl-benzyl-dithiocarbonate 
• 87234-43-3 2-propenyl ethaneimidothiolate hydrobromide 
• 100-44-7 benzyl chloride 
• 96989-38-7 N-methyl-N-<(2-propenylthio)methylene>methanaminium bromide 
• 32894-07-8 S-benzyl thioacetimidate hydrochloride 
• 41795-82-8 S-benzyl thioacetimidate hydrobromide 
• 69614-87-5 N-methyl-N-<<(phenylmethyl)thio>methylene>methanaminium chloride 
• 100-51-6 benzyl alcohol 
• 538-28-3 S-benzylisothiourea hydrochloride 
• 35466-83-2 allyl methyl carbonate 

Downstream Products

• 3012-37-1 benzyl thiocyanate 
• 100-39-0 benzyl bromide 
• 57-06-7 N-allyl isothiocyanate 
• 75238-63-0 Benzyl-1-butinyl-sulfid 
• 63297-72-3 1-phenyl-1-(methylthio)-3-butene 
• 75238-62-9 benzyl but-3-en-2-yl sulfide 
• 140927-78-2 3-chloro-2-methoxypropyl benzyl sulfide 
• 13284-96-3 2-propenyl benzyl sulfoxide 
• 187737-37-7 propene 
• 100-53-8 phenylmethanethiol 
• 26551-50-8 1-benzylsulfanyl-3-chloro-propan-2-ol 
• 78286-78-9 (2-Benzylsulfanyl-1-methyl-ethyl)-phenyl-amine 
• 898267-76-0 trans-3-benzylsulfonyl-2-propene acetate 
• 889862-39-9 trans-3-benzylsulfonyl-2-propen-1-ol 

Relevant academic research and scientific papers

Sulfur ylides generated from the reaction of adamantylidene and phenylcarbene with sulfur substrates

Reaction of adamantylidene and phenylcarbene with ethylthiol, ethylene dithiol, allylethylsulfide, allylphenylsulfide, and trimethylenesulfide involves the formation of a sulfur ylide intermediate, followed by H-migration, 2,3-sigmatropic shift, or ring opening to give sulfides. The sulfur ylide formed in the reaction of phenylcarbene with trimethylenesulfide is directly observed by laser flash photolytic techniques.

Yb(iii)-catalysedsyn-thioallylation of ynamides

Reported herein is asyn-thioallylation of ynamides incorporating a sulfide moiety at the α-position and an allyl group at the β-position of the ynamide. The transformation is successful under ytterbium(iii)-catalysis, providing access to highly substituted thioamino-skipped-dienes with broad substrate scope. Thus, tetrasubstituted olefins (with four different functional groups: amide, phenyl, thioaryl/alkyl, and allyl on the carbon centers) are made in a single step from readily accessible ynamides, preserving complete atom economy. The reaction can be extended to the synthesis of selenoamino dienes by ynamidesyn-selenoallylation. DFT studies and control experiments provide insight into the reaction mechanism.

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

Chemoselective rearrangement reactions of sulfur ylide derived from diazoquinones and allyl/propargyl sulfides

Here, we describe three types of rearrangement reactions of sulfur ylide derived from diazoquinones and allyl/ propargyl sulfides. With Rh2(esp)2 as the catalyst, diazoquinones react with allyl/propargyl sulfides to form a sulfur ylide, which undergoes a chemoselective tautomerization/[2,3]-sigmatropic rearrangement reaction, a Doyle?Kirmse rearrangement/Cope rearrangement cascade reaction, or a Doyle?Kirmse rearrangement/elimination reaction, depending on the substituent of the sulfides. The protocol provides alkenyl and allenyl sulfides and multisubstituted phenols with moderate and high yields.

Ruthenium-catalyzed decarboxylative C-S cross-coupling of carbonothioate: synthesis of allyl(aryl)sulfide

A novel ruthenium-catalyzed decarboxylative cross-coupling of carbonothioate is disclosed. This method provides straightforward access to the corresponding allyl(aryl)sulfide derivatives in generally good to excellent yields under mild conditions and feat

Aqueous hemin catalyzed sulfonium ylide formation and subsequent [2,3]-sigmatropic rearrangements

A mild hemin catalytic system for sulfonium ylide generation via a metal carbenoid and a subsequent [2,3]-sigmatropic rearrangement reaction in aqueous solvent is well-established, with the assistance of cyclodextrin (CD) and Triton X-100. The protocol displays high catalytic activity with a broad substrate scope of aryl/alkyl allyl sulfides and diazo reagents, affording homoallyl sulfide products in up to 99% yield. Notably, this catalytic system is successful for water-insoluble allyl sulfides but ineffective for allyl amines or allyl ethers. Moreover, an unprecedented cascade reaction of sulfonium ylide formation, [2,3]-sigmatropic rearrangement and C-H insertion was reported.

Method of manufacturing compds. Allylnaphthol

PROBLEM TO BE SOLVED: To provide a production method of an allyl compound of carrying out the dehydration allylation of a substrate having S, C or N which is a nucleophilic atom, especially S under the presence of a catalyst system consisting of a catalyst precursor having a specific structure and a specific ligand. SOLUTION: The production method of allyl compounds comprises as follow. A catalyst precursor chosen from Formula (1) and Formula (2) and a ligand are mixed, or a catalyst precursor, an allyl alcohol, and a ligand are mixed, then allyl alcohols and a substrate are blended and made to react. The ligand is quinaldic acid or picolinic acid, and the substrate is thiols, thiocarboxylic acids or the like. [Ru(C5H5)(CH3CN)3]PF6(1). [Ru[C5(CH3)5](CH3CN)3]PF6(2). COPYRIGHT: (C)2012,JPOandINPIT

Rh(II)-Catalyzed [2,3]-Sigmatropic Rearrangement of Sulfur Ylides Derived from Cyclopropenes and Sulfides

(Chemical Equation Presented) A new type of Rh2(OAc)4-catalyzed [2,3]-sigmatropic rearrangement of sulfur ylides is reported. A series of cyclopropenes were successfully employed for [2,3]-sigmatropic rearrangement by a reaction with either allylic or propargylic sulfides. Under the optimized conditions, the reaction afforded the products in moderate to excellent yields. In these transformations, the vinyl metal carbenes generated in situ from the cyclopropenes were effectively trapped by sulfides, resulting in the formation of corresponding products upon [2,3]-sigmatropic rearrangements.

Efficient reduction of sulfoxides with NaHSO3 catalyzed by I2

An efficient method for the deoxygenation of sulfoxides into their corresponding sulfides at room temperature using NaHSO3 in the presence of catalytic I2 has been reported.

Expanding the horizon of intermolecular trapping of in situ generated α-oxo gold carbenes: Efficient oxidative union of allylic sulfides and terminal alkynes via C-C bond formation

With a new P,S-bidentate phosphine as the ligand to gold(i), the α-oxo gold carbenes generated in situ via gold-catalyzed intermolecular oxidation of terminal alkynes were effectively trapped by various allylic sulfides, resulting in the formation of α-aryl(alkyl)thio-γ,δ- unsaturated ketones upon facile [2,3]sigmatropic rearrangements. This journal is the Partner Organisations 2014.