Welcome to LookChem.com Sign In|Join Free
  • or
N,N-dimethyl-4-nitrobenzamide is an organic compound with the chemical formula C9H10N2O3. It is a derivative of benzamide, featuring a nitro group at the para position and two methyl groups attached to the nitrogen atom. This yellow crystalline solid is soluble in organic solvents such as ethanol and acetone. N,N-dimethyl-4-nitrobenzamide is synthesized through the reaction of 4-nitrobenzoic acid with dimethylamine, and it is used as an intermediate in the production of various pharmaceuticals and agrochemicals. Its chemical properties include reactivity towards nucleophiles due to the presence of the nitro group, which can undergo reduction or substitution reactions.

7291-01-2

Post Buying Request

7291-01-2 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

7291-01-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7291-01-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,9 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7291-01:
(6*7)+(5*2)+(4*9)+(3*1)+(2*0)+(1*1)=92
92 % 10 = 2
So 7291-01-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2O3/c1-10(2)9(12)7-3-5-8(6-4-7)11(13)14/h3-6H,1-2H3

7291-01-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-dimethyl-4-nitrobenzamide

1.2 Other means of identification

Product number -
Other names N,N-dimethyl-p-nitrobenzoamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7291-01-2 SDS

7291-01-2Relevant academic research and scientific papers

Cobalt-Catalyzed Deoxygenative Hydroboration of Nitro Compounds and Applications to One-Pot Synthesis of Aldimines and Amides

Gudun, Kristina A.,Zakarina, Raikhan,Segizbayev, Medet,Hayrapetyan, Davit,Slamova, Ainur,Khalimon, Andrey Y.

supporting information, p. 601 - 611 (2021/11/30)

The commercially available and bench-stable Co(acac)2 ligated with bis[(2-diphenylphosphino)phenyl] ether (dpephos) was employed for selective room temperature hydroboration of nitro compounds with HBPin (TOF up to 4615 h?1), tolerating halide, hydroxy, amino, ether, ester, lactone, amide and heteroaromatic functionalities. These reactions offered a direct access to a variety of N-borylamines RN(H)BPin, which were in situ treated with aldehydes and carboxylic acids to produce a series of aldimines and secondary carboxamides without the need for dehydrating and/or coupling reagents. Combination of these transformations in a sequential one-pot manner allowed for direct and selective synthesis of aldimines and secondary carboxamides from readily available and inexpensive nitro compounds.

One-pot synthesis of a highly disperse core-shell CuO-alginate nanocomposite and the investigation of its antibacterial and catalytic properties

Habibi, Hassan,Mansourinejhad, Sanam,Saberi, Dariush,Shadi, Ahmad

, p. 199 - 211 (2021/12/30)

In this study, sodium alginate was extracted from Sargassum algae, collected from coastal waters of Bushehr, Persian Gulf, Iran and used as a stabilizing and wrapping agent for CuO nanoparticles. The synthesized nanocomposite was characterized by some spectroscopic and microscopic techniques, such as IR, XRD, Uv-vis, BET, BJH, zeta potential, SEM, TEM, HR-TEM, and XPS. The antibacterial effects of the CuO-alginate nanocomposite against some bacteria, isolated from a burn wound, were evaluated. The results showed that this nanocomposite had better antibacterial effects than its components onPseudomonas aeruginosaATCC 27853,Staphylococcus aureusATCC 12600,Streptococcus pyogenesATCC 19615, andStaphylococcus epidermidisATCC 49461. Among these,Staphylococcus aureusATCC 12600 was the most sensitive one to this nanocomposite, with the lowest minimum inhibitory concentration (2.08 mg mL?1) observed. Moreover, the synthesized nanocomposite showed good catalytic activity in the oxidative coupling of carboxylic acids withN,N-dialkylformamides toward the synthesis of amides.

Deoxygenative hydroboration of primary, secondary, and tertiary amides: Catalyst-free synthesis of various substituted amines

Yi, Jaeeun,Kim, Hyun Tae,Jaladi, Ashok Kumar,An, Duk Keun

supporting information, p. 129 - 132 (2021/11/17)

Transformation of relatively less reactive functional groups under catalyst-free conditions is an interesting aspect and requires a typical protocol. Herein, we report the synthesis of various primary, secondary, and tertiary amines through hydroboration of amides using pinacolborane under catalyst-free and solvent-free conditions. The deoxygenative hydroboration of primary and secondary amides proceeded with excellent conversions. The comparatively less reactive tertiary amides were also converted to the corresponding N,N-diamines in moderate yields under catalyst-free conditions, although alcohols were obtained as a minor product.

Palladium-Catalyzed Aminocarbonylation of Aryl Halides with N,N-Dialkylformamide Acetals

Hirata, Shuichi,Osako, Takao,Uozumi, Yasuhiro

, (2021/10/05)

We developed a protocol for the palladium-catalyzed aminocarbonylation of aryl halides using less-toxic formamide acetals as bench-stable aminocarbonyl sources under neutral conditions. Various aryl (including heteroaryl) halides reacted with N,N-dialkylformamide acetals in the presence of a catalytic amount of tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct and xantphos to give the corresponding aromatic carboxamides at 90–140 °C without any activating agents or bases in up to quantitative chemical yield. This protocol was applied to aryl bromides, aryl iodides, and trifluoromethanesulfonic acid, as well as to relatively less-reactive aryl chlorides. A wide range of functionalities on the aromatic ring of the substrates were tolerated under the aminocarbonylation conditions. The catalytic aminocarbonylation was used to prepare the insect repellent N,N-diethyl-3-methylbenzamide as well as a synthetic intermediate of the dihydrofolate reductase inhibitor triazinate.

Ipso Nitration of Aryl Boronic Acids Using Fuming Nitric Acid

Baucom, Kyle D.,Brown, Derek B.,Caille, Seb,Murray, James I.,Quasdorf, Kyle,Silva Elipe, Maria V.

supporting information, (2021/06/30)

The ipso nitration of aryl boronic acid derivatives has been developed using fuming nitric acid as the nitrating agent. This facile procedure provides efficient and chemoselective access to a variety of aromatic nitro compounds. While several activating agents and nitro sources have been reported in the literature for this synthetically useful transformation, this report demonstrates that these processes likely generate a common active reagent, anhydrous HNO3. Kinetic and mechanistic studies have revealed that the reaction order in HNO3 is >2 and indicate that the ?NO2 radical is the active species.

Benzamide derivatives as protein kinase inhibitors

-

Paragraph 0132; 0139-0141, (2020/09/16)

The present invention relates to a benzamide compound having protein kinase inhibitory activity, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for preventing and treating diseases caused by abnormal cell growth containing th

Synthesis method of tertiary amide compound

-

Paragraph 0024, (2021/01/04)

The invention provides a synthesis method of a tertiary amide compound, which comprises the following steps: reacting acyl chloride and N, N-disubstituted-4-oxopiperidinium salt used as raw materials,tris (2, 2 '-dipyridyl) ruthenium dichloride (II) used as a photosensitizer and triethylamine used as an alkali at room temperature for 3-12h under the protection of N2, and purifying to obtain the tertiary amide compound. The reaction is completed under the illumination condition, the cost is low, and the efficiency is high; the synthesis operation is simple and convenient, the reaction conditions are mild, and a method for synthesizing tertiary amide compounds without using harsh high-temperature heating conditions is developed; N, N-disubstituted-4-oxopiperidinium salt is adopted as a reaction raw material, is relatively stable in property and convenient to store, and is particularly suitable for industrial large-scale production.

Pyrrolopyrimidine compound, pharmaceutical composition containing thereof, and preparation method and applications

-

Paragraph 0295-0299, (2019/11/29)

The invention relates to a pyrrolopyrimidine compound represented by formula I, a pharmaceutical composition containing thereof, and a preparation method and applications in preventing or treating Weel protein kinase related diseases.

Oxidative amidation of benzyl alcohol, benzaldhyde, benzoic acid styrene and phenyl acetylene catalyzed by ordered mesoporous HKUST-1-Cu: Effect of surface area on oxidative amidation reaction

Mohebali, Haleh,Mahjoub, Ali Reza,Karimi, Meghdad,Heydari, Akbar

, (2019/03/29)

HKUST-1-Cu synthesized in the presence and absence of P-123 trough solvotermal method. After characterization using some different microscopic and spectroscopic techniques such as XRD, FT-IR, SEM, ICP, BET and TEM its catalytic activity was investigated in the oxidative coupling of benzyl alcohol, benzaldhyde, benzoic acid, styrene and phenyl acetylene with N,N-dialkylformamides for the preparation of N,N-dimethylformamides. Different derivatives of tertiary amides were synthesized in moderate to good yields in the presence of just ~0.28?mol% of this catalytic system. Reusability of the synthesized catalysts was examined and catalysts were reusable for 8 times without significant decrease in optimized conditions.

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

-

, (2019/02/13)

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured.The variables shown in Formula AA are as defined in the claims. The compounds of formula AA are NLRP3 activity modulators and, as such, can be used in the treatment of metabolic disorders (e.g. Type 2 diabetes, atherosclerosis, obesity or gout), a disease of the central nervous system (e.g. Alzheimer's disease, multiple sclerosis, Amyotrophic Lateral Sclerosis or Parkinson's disease), lung disease (e.g. asthma, COPD or pulmonary idiopathic fibrosis), liver disease (e.g. NASH syndrome, viral hepatitis or cirrhosis), pancreatic disease (e.g. acute pancreatitis or chronic pancreatitis), kidney disease (e.g. acute kidney injury or chronic kidney injury), intestinal disease (e.g. Crohn's disease or Ulcerative Colitis), skin disease (e.g. psoriasis), musculoskeletal disease (e.g. scleroderma), a vessel disorder (e.g. giant cell arteritis), a disorder of the bones (e.g. osteoarthritis, osteoporosis or osteopetrosis disorders), eye disease (e.g. glaucoma or macular degeneration), a disease caused by viral infection (e.g. HIV or AIDS), an autoimmune disease (e.g. Rheumatoid Arthritis, Systemic Lupus Erythematosus or Autoimmune Thyroiditis), cancer or aging.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 7291-01-2