74322-80-8

Basic information

• Product Name: (2E)-1,4-Bis(4-broMophenyl)-2-butene-1,4-dione
• Synonyms: (2E)-1,4-Bis(4-broMophenyl)-2-butene-1,4-dione
• CAS NO: 74322-80-8
• Molecular Formula: C₁₆H₁₀Br₂O₂
• Molecular Weight: 394.0574
• Product Categories: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 74322-80-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: (2E)-1,4-Bis(4-broMophenyl)-2-butene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1,4-Bis(4-broMophenyl)-2-butene-1,4-dione(74322-80-8)
• EPA Substance Registry System: (2E)-1,4-Bis(4-broMophenyl)-2-butene-1,4-dione(74322-80-8)

Safety Data

• Hazardous Substances Data: 74322-80-8(Hazardous Substances Data)

Usage

Chemical Properties

Light Brown Solid

Uses

Intermediate in the preparation of Furamidine (F863600) an antimicrobial and antiparasitic agent.

Upstream product

• 108-86-1 bromobenzene 
• 627-63-4 fumaryl dichloride 
• 99-90-1 para-bromoacetophenone 
• 99-73-0 para-bromophenacyl bromide 
• 6332-09-8 1.4-bis-(4-bromo-phenyl)-butene-(2c)-dione-(1.4) 
• 64-19-7 acetic acid 
• 67-66-3 chloroform 
• 7553-56-2 iodine 
• 7647-01-0 hydrogenchloride 
• 7446-08-4 selenium(IV) oxide 
• 64-17-5 ethanol 
• 2461-83-8 1,4-bis(4-bromophenyl)-1,4-butanedione 
• 1777-57-7 p-bromobenzoylmethylenetriphenylphosphorane 
• 36710-35-7 2,5-bis(4-bromophenyl)furan 

Downstream Products

• 6332-09-8 1.4-bis-(4-bromo-phenyl)-butene-(2c)-dione-(1.4) 
• 2461-83-8 1,4-bis(4-bromophenyl)-1,4-butanedione 
• 74322-75-1 [6-(4-Bromo-benzoyl)-2-diethylamino-cyclohex-3-enyl]-(4-bromo-phenyl)-methanone 
• 36710-35-7 2,5-bis(4-bromophenyl)furan 
• 55368-36-0 2,5-di(4-bromophenyl)-1H-pyrrole 
• 61829-88-7 2,5-bis-(4-bromo-phenyl)-3,4-dichloro-furan 
• 173420-64-9 1,4-bis-(4-bromo-phenyl)-2-methoxy-butane-1,4-dione 

Relevant articles and documents

Visible-Light-Driven Stereoselective Annulation of Alkyl Anilines and Dibenzoylethylenes via Electron Donor-Acceptor Complexes

A catalyst-free, stereoselective visible-light-driven annulation reaction between alkenes and N,N-substituted dialkyl anilines for the synthesis of substituted tetrahydroquinolines is presented. The reaction is driven by the photoexcitation of an electron donor-acceptor (EDA) complex, and the resulting products are obtained in good to high yields with complete diastereoselectivity. Mechanistic rationale and photochemical characterization of the EDA-complex are provided.

Asymmetric diastereoselective synthesis of spirocyclopropane derivatives of oxindole

A new asymmetric organocatalytic synthesis of spirocyclopropane oxindoles has been developed. The method is based on the Michael addition of N-Boc-protected 3-chlorooxindole to unsaturated 1,4-dicarbonyl compounds, affording trans-substituted spirocyclopropane oxindole derivatives in high diastereo- and enantioselectivity. Copyright

Lewis acid-catalyzed one-pot, three-component route to chiral 3,3′-bipyrroles

(Chemical Equation Presented) 3,3′-Bipyrroles 3 could be synthesized using a double Michael addition reaction involving diaroyl acetylene 1 and the appropriate 1,3-dicarbonyls 2 using ammonium acetate as a nitrogen source. The axial chirality of bipyrrole was anticipated from the X-ray crystal structure and DFT calculations and confirmed by separating the racemates on a chiral column and subsequent CD spectra of the enantiomers. The absolute configuration of the enantiomers was achieved by theoretical CD spectra calculation using the ZINDO method.