745041-30-9Relevant academic research and scientific papers
Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile
Toba, Tetsuya,Murata, Kenji,Futamura, Junko,Nakanishi, Kyoko,Takahashi, Bitoku,Takemoto, Naohiro,Tomino, Minako,Nakatsuka, Takashi,Imajo, Seiichi,Goto, Megumi,Yamamura, Takashi,Miyake, Sachiko,Annoura, Hirokazu
scheme or table, p. 2850 - 2859 (2012/07/01)
A series of truncated analogs of α-galactosylceramide with altered ceramide moiety was prepared, and evaluated for Th2-biased response in the context of IL-4/IFN-γ ratio. Phytosphingosine-modified analogs including cyclic, aromatic and ethereal compounds
Synthesis of α-S-galactosylceramides with a truncated sphingoid chain
Zhu, Xiangming,Dere, Ravindra T.,Jiang, Junyan
, p. 4971 - 4974 (2011/10/05)
We present here a convenient synthesis of the truncated sphingoid iodide 15 from d-galactose, in which Mitsunobu reaction was utilized to retrieve successfully an unwanted intermediate, thereby increasing greatly the synthetic efficiency. Subsequent react
GLYCOLIPID DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, INTERMEDIATES FOR SYNTHESIS THEREOF, AND PROCESS FOR PRODUCTION OF THE INTERMEDIATES
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Page/Page column 15-16; 31, (2008/06/13)
Novel glycolipid derivatives, where the substituent of the sphingosine base part is a short carbon chain alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group and
Total synthesis of an immunosuppressive glycolipid, (2S,3S,4R)-1-O- (α-D-galactosyl)-2-tetracosanoylamino-1,3,4-nonanetriol
Murata, Kenji,Toba, Tetsuya,Nakanishi, Kyoko,Takahashi, Bitoku,Yamamura, Takashi,Miyake, Sachiko,Annoura, Hirokazu
, p. 2398 - 2401 (2007/10/03)
(Chemical Equation Presented) A practical and efficient total synthesis of (2S,3S,4R)-1-O-(α-D-galactosyl)-2-tetracosanoylamino-1,3,4-nonanetriol, OCH 1b, a potential therapeutic candidate for Th1-mediated autoimmune diseases, is described. The synthesis
