935-05-7Relevant academic research and scientific papers
Synthetic method of alpha-cyanobenzoxime sodium
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Paragraph 0022, (2021/01/29)
The invention relates to a synthesis method of alpha-cyanobenzoxime sodium, which comprises the following two steps: step 1, reacting an alcohol (alcohol: sodium nitrite: acid = 1: 1-3.5: 1-5) solution and a sodium nitrite (alcohol: sodium nitrite: acid =
Dual Catalysis for the Aerobic Oxidation of Benzyl Alcohols – Nitric Acid and Fluorinated Alcohol
Mo?ina, ?tefan,Stavber, Stojan,Iskra, Jernej
, p. 448 - 452 (2017/02/05)
Benzyl alcohols were oxidized with oxygen to aldehydes in excellent yields with high selectivities at room temperature. Dual catalysis was operative with HNO3as the oxidant and precursor of the nitrogen oxides and with the use of 1,1,1,3,3,3-hexafluoro-2-propanol as a template catalyst and solvent. Fluorinated alcohols also increased the selectivity by inhibiting further oxidation to benzoic acids. Activation of nitric acid catalyzed aerobic oxidation by the fluorinated solvent made the use of 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) or a metal catalyst superfluous.
Silica-supported 4-OH-TEMPO/NOx: A novel and efficient catalyst for aerobic oxidation of alcohols
Zhang, Hua,Fu, Luoling
, p. 610 - 619 (2014/01/17)
Silica-supported 4-OH-2,2,6,6-tetramethylpiperidyl-1-oxy/NOx (4-OH-TEMPO was immobilized on the surface of silica using the sol-gel method, and then it adsorbed NOx), as a heterogeneous catalyst, has exhibited good catalytic performance in alcohol oxidation. A broad range of alcohols were oxidized to their corresponding aldehydes or ketones with more than 99% selectivity and 99% conversion rate by such a catalyst system at room temperature in air. NOx not only acted as an electron bridge between O2 and 4-OH-TEMPO but also were conducive to the formation of the aldehydes as active component. A possible mechanism for oxidation of alcohols promoted by silica-supported 4-OH-TEMPO/NOx was supposed. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.] Copyright
Acid-assisted catalytic oxidation of benzyl alcohol by NOx with dioxygen
Sheng, Xuebin,Ma, Hong,Chen, Chen,Gao, Jin,Yin, Guochuan,Xu, Jie
experimental part, p. 1189 - 1192 (2010/11/19)
Efficient transformation of alcohols to the corresponding aldehydes is an important process in organic synthesis and industry. In the absence of transition metal ion, an acid-activated NOx has been explored for the catalytic oxidation of benzyl
Novel and highly selective conversion of alcohols and thiols to alkyl nitrites with triphenylphosphine/2,3-dichloro-5,6-dicyanobenzoquinone/Bu 4NNO2 system
Akhlaghinia, Batool,Pourali, Ali Reza
, p. 1747 - 1749 (2007/10/03)
Alkyl nitrites were prepared in good to excellent yields by treatment of alcohols and thiols with triphenylphosphine/2,3-dichloro-5,6- dicyanobenzoquinone/Bu4NNO2 in acetonitrile. This method is highly selective for the conversion of primary alcohols to alkyl nitrites in the presence of secondary and tertiary alcohols and thiols.
Nitrosamines, N-nitrosoamides, and diazonium ions from tri-N-substituted amidines
Loeppky,Yu
, p. 3263 - 3266 (2007/10/02)
N'-Substituted pyrrolidyl amidines react with HNO2 at 37°C. to give N-nitrosopyrrolidine, N-nitrosoamides, and diazonium derived products.
Hydrolysis, Nitrosyl Exchange, and Synthesis of Alkyl Nitrites
Doyle, Michael P.,Terpstra, Jan W.,Pickering, Ruth A.,LePoire, Diane M.
, p. 3379 - 3382 (2007/10/02)
Alkyl nitrites undergo relatively slow hydrolysis in phosphate-buffered aqueous media under neutral conditions with small but significant dependence of reactivity on structure.However, rapid nitrosyl exchange with alcohols is observed, and equilibrium constants for this transformation exhibit remarkable correlation with equilibrium constants for nitrosyl exchange of alcohols with nitrosyl chloride and with nitrous acid. tert-Butyl nitrite has the greatest driving force for nitrosyl transfer among the 12 alkyl nitrites examined, and this capability is used for the synthesis of alkyl nitrites derived from steroidal alcohols and of alkyl thionitrites.
Elimination, Fragmentation, and Proton Transfer in 1,3-Dithianes and 1,3-Dithiolanes in the Gas Phase
Bartmess, John E.,Hays, Robert L.,Khatri, Hiralal N.,Misra, Raj N.,Wilson, Stephen R.
, p. 4746 - 4751 (2007/10/02)
The gas-phase negative ion-molecule chemistry of 1,3-dithianes and 1,3-dithiolanes differs considerably from the in solution.When treated with anionic bases, 1,3-dithiane undergoes successive elimination reactions giving thiolates, in competition with deprotonation at the 2-carbon, which is the sole solution phase reaction channel.The appearence of the various product ions with changing base strength agrees with their calculated thermochemical onset.The gase-phase acidity of 1,3-dithiane is measurable if the elimination reaction is blocked by gem-dimethyl substitution at the 5 carbon.For 1,3-dithiolane, no deprotonation product is pbserved; even at thermochemical treshold, cycloreversion to RCS2- and ethylene occurs.This competes with successive elimination to thiolates, as with the six-membered ring.The differences between the gas phase and solution reactivities are rationalized in terms of counterion effects.
