Hydrogenation of aryl ketones in the presence of water-soluble diamine-complexed transition metals (neutral pH)

July 18, 2024

• Title:       

  Hydrogenation of aryl ketones in the presence of water-soluble diamine-complexed transition metals (neutral pH)

• Image Source:

  New water-soluble diamine complexes as catalysts for the hydrogenation of ketones under hydrogen pressure

• Mark:

  Table 1

• Associated context:

  In the case of ligand 1, good catalytic activity was observed in the reduction of aromatic oxo esters and ketones (Table 1, entries  1, 3, 6), but the presence of electron-donating substituents in the para position (entries 7-9) or the use of a lower metal/substrate ratio (entry 4) led to a significant retar-dation of the reduction.