Plausible reaction pathway for thiocyanation of arylboronic acids with TMSNCS

July 30, 2024

• Title:       

  Plausible reaction pathway for thiocyanation of arylboronic acids with TMSNCS  

• Image Source:

  A mild copper-catalyzed aerobic oxidative thiocyanation of arylboronic acids with TMSNCS

• Mark:

  Figure 1

• Associated context:

  From these results, a plausible reaction mechanism is proposed in Figure 1. It was assumed that  LCu(I)Cl A was first exchanged with the in situ generated NCS-anion to form reactive LCu(I)SCN B,  which could be oxidized by O2 to yield bis(µ-oxo)-dicopper (III) complex C. In this step, the existence of the diamine ligand TMEDA (L) was essential.