Metabolic and elimination products of [14C]PHOTODIELDRIN (cas 13366-73-9) from bluegill fish

Add time:07/25/2019    Source:sciencedirect.com

Bluegill fish, following exposure to [14C]photodieldrin eliminated 50% of the absorbed radioactivity in 3 weeks. Analysis of the products revealed that about 27% of the eliminated radioactivity was due to the unaltered photodieldrin while the rest consisted of at least 11 metabolites in free and conjugated forms. Photodieldrin ketone was the major excretory product. Solvent extracts of the whole fish examined showed 4 metabolites in addition to about 90% of the unmetabolized photodieldrin. The ketone derivative was the most predominant of the metabolic products.

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