Studies of the peptic degradation of bovine bradykininogen (cas 12642-94-3)☆

Add time:08/15/2019    Source:sciencedirect.com

Investigations into the manner in which bradykinin is linked in the bradykininogen molecule has led to the degradation of bovine bradykininogen by the enzyme pepsin. The degradative products include dialyzable polypeptides which contain bradykinin of bradykinin-like peptides as part of their structure. Partial purification of these peptides has been accomplished by Dowex 1-X2 chromatography. Purification has been aided by the use of p-toluenesulfonic acid, an agent found to protect, bradykinin and bradykinin-like peptides during concentration procedures.

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