Phenethyl caffeate (cas 104594-70-9) benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells
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Add time:08/17/2019 Source:sciencedirect.com
AimsPhenethyl caffeate (cas 104594-70-9) benzoxanthene lignan (PCBL) is a synthetic compound with DNA interacting, antiangiogenic, antiproliferative and tumor cell death inducing abilities. Though PCBL exhibits the qualities of a prospective antitumor agent, the basic mechanism of PCBL induced cell death remains unknown. This study aims to analyze the molecular mechanisms of PCBL induced cell death in tumor cells to further substantiate its antitumor abilities.
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