Conversion of uridine into 2′-O-(2-methoxyethyl)uridine and 2′-O-(2-methoxyethyl)cytidine

Add time:08/22/2019    Source:sciencedirect.com

Reaction between aluminium 2-methoxyethoxide and 2,2′-anhydro-1-β-d-arabinofuranosyluracil 6 gives 2′-O-(2-methoxyethyl)uridine 9 in high yield. Compound 9 is converted into 2′-O-(2-methoxyethyl)cytidine 11 in good yield.

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