111In-DOTA-ANNEXIN V (cas 136107-94-3) for imaging of apoptosis during HSV1-tk/GCV prodrug activation gene therapy in mice with NG4TL4 sarcoma
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Add time:08/30/2019 Source:sciencedirect.com
IntroductionApoptosis has been suggested as a cytocidal mechanism of the HSV1-tk-expressing cells when exposed to ganciclovir (GCV). This study evaluated the efficacy of 111In-labeled Annexin V for monitoring tumor responses during prodrug activation gene therapy with HSV1-tk and GCV.
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