l-argininamide (cas 16709-23-2) improves the refolding more effectively than l-arginine

Add time:09/08/2019    Source:sciencedirect.com

l-Arginine (Arg) is a widely used additive for suppressing protein aggregation during refolding. Systematic screening of Arg analogs provides superior additives that enhance the refolding yield more effectively than Arg. The refolding yield of hen egg lysozyme in the presence of 500 mM l-argininamide (ArgAd) increases 1.7-fold higher than Arg. Thermal unfolding experiments indicate that ArgAd has a greater denaturing effect than Arg. The refolding yield positively relates to the net charge of Arg analogs. Moreover ArgAd was also effective for the refolding of bovine carbonic anhydrase. High potency to increase the refolding yield of ArgAd compared to Arg results from high positive net charge and the denaturing property.

We also recommend Trading Suppliers and Manufacturers of argininamide (cas 16709-23-2). Pls Click Website Link as below: cas 16709-23-2 suppliers

Prev:Red-fluorescent argininamide (cas 16709-23-2)-type NPY Y1 receptor antagonists as pharmacological tools
Next:Regular articleSolution structure of the HIV-2 TAR-argininamide (cas 16709-23-2) complex1☆)