7211-39-4Relevant articles and documents
Dimethylphosphinato and dimethylarsinato complexes of palladium(II), [Pd(Me2PO2)2]3and Pd(Me 2AsO2)2, and their adducts
Ioannou, Panayiotis V.
, p. 1347 - 1353 (2010)
The complexes [Pd(Me2PO2)2]3 and Pd(Me2AsO2)2 were prepared from the corresponding acids and palladium(II) acetate. Their structures were deduced by IR and NMR spectroscopy. Addition of pyridine and 2,2'-bipyridine to [Pd(Me 2PO2)2]3 gave the adducts Pd(Me 2PO2)2py2 and Pd(Me 2PO2)2bipy, which were characterized by 1H NMR spectroscopy. Addition of nicotinic acid and nicotinamide in water gave the adducts Pd(Me2PO2)2L 2, whereas in methanol the adducts Pd(Me2PO 2)2L were obtained. The cacodylate containing complex formed the adducts Pd(Me2AsO2)2py and Pd(Me2AsO2)2bipy1/2, which are unstable in CDCl3. Triphenylphosphine deoxygenated both Pd(Me2MO 2)2 complexes, but the palladium(II) containing products could not be isolated, The expected Pd(Me2P-O)2 reacted further and gave many products, whereas the anticipated Pd(Me 2As-O)2 did not bind triphenylphosphine.
Highly Enantioselective Synthesis of Phosphorus-Containing ?-Benzosultams by Bifunctional Phosphonium Salt-Promoted Hydrophosphonylation
Zhang, Song,Feng, Zhenghuai,Jiang, Chunhui,Yu, Xiaojun,Pan, Jianke,Du, Juan,Jiang, Zhiyu,Chen, Yuan,Wang, Tianli
supporting information, p. 11285 - 11290 (2021/07/02)
?-Benzosultam derivatives are potential drug candidates with diverse biological activities. A series of chiral ?-benzosultams bearing phosphorus functionalities was synthesized by catalytic asymmetric hydrophosphonylation in the presence of a bifunctional phosphonium salt catalyst. The desired hydrophosphonylation products were obtained in good yields with high enantioselectivities, and scale-up reactions and further derivations were successfully accomplished. Some control experiments were also conducted to elucidate the plausible reaction mechanism of this chemical transformation.
DIMETHYLPHOSPHINE OXIDE COMPOUND
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Paragraph 0047, (2021/02/25)
Disclosed is an application of a series of dimethylphosphine oxide compounds in the preparation of an LRRK2 kinase activity inhibitor-related drug, specifically an application of the compound shown in formula (I) or a pharmaceutically acceptable salt thereof in the preparation of an LRRK2 kinase activity inhibitor-related drug.
TYK2 INHIBITORS AND USES THEREOF
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Paragraph 00662; 00663, (2018/04/27)
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
USE OF PHOSPHINE OXIDE COMPOUNDS IN A SEMICONDUCTING LAYER COMPRISED IN AN ELECTRONIC DEVICE
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Page/Page column 49; 50, (2018/12/13)
The present invention relates to the use of a compound represented by the general formula (I) wherein A1 and A2 are independently selected from C1 to C60 carbon-containing groups; A3 to A9 are independently selected from hydrogen, C1 to C60 carbon-containing groups, or halogen; R1 and R2 are independently selected from C1 to C60 carbon-containing groups which are attached to the phosphorous atom by a sp3-hybridized carbon atom; X is a single covalent bond or a spacer group consisting of 1 to 120 covalently bound atoms; in a semiconducting layer comprised in an electronic device, a respective semiconducting layer, a respective electronic device and respective compounds.
ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER
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Page/Page column 52, (2018/12/13)
The present invention relates to a compound of formula 1 and an organic electronic device comprising an organic semiconductor layer, wherein at least one organic semiconductor layer comprises a compound of formula (1), wherein L1 has the formula (2) and L2 has the formula (3), wherein L1 and L2 are bonded at "*" via a single bond independently to the same or different arylene groups or heteroarylenes group of Ar1; and wherein X1, X2 are independently selected from O, S and Se; Ar1 is selected from substituted or unsubstituted C20 to C52 arylene or C14 to C64 heteroarylene, wherein the substituent of the substituted C20 to C52 arylene or C14 to C64 heteroarylene are independently selected from C1 to C12 alkyl, C1 to C12 alkoxy, CN, halogen, OH, C6 to C25 aryl and C2 to C21 heteroaryl; R1, R2 are independently selected from substituted or unsubstituted C1 to C16 alkyl, wherein the substituent of substituted C1 to C16 alkyl is selected from C6 to C18 arylene or C2 to C12 heteroarylene; R3, R4 are independently selected from substituted or unsubstituted C1 to C16 alkyl, substituted or unsubstituted C6 to C18 arylene, C2 to C20 heteroarylene, wherein the substituent of substituted C1 to C16 alkyl, the substituent of the substituted C6 to C18 arylene, C2 to C20 heteroarylene are independently selected from C6 to C18 arylene or C2 to C12 heteroarylene; n is selected from 1 to 5, wherein n is an integer number.
ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS
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Page/Page column 80; 81, (2017/06/29)
The present invention relates to an. organic semiconductive layer which is an electron transport layer and/or an electron injection layer and/or an n-type charge generation layer, the organic semiconductive layer comprising at least one compound of formula (1) wherein R1 and R2 are each independently selected from C1 to C16 alkyl; Ar1 is selected from C6 to C14 arylene or C3 to C12 heteroarylene; Ar2 is independently selected from C14 to C40 arylene or C8 to C40 heteroarylene; R3 is independently selected from H, C1 to C12 alkyl or C10 to C20 aryl; wherein each of Ar1, Ar2 and R3 may each independently be uesubstituted or substituted with at least one C1 to C12 alky group; n is 0 or 1; and m is 1 in case of n = 0; and m is 1 or 2 in case of n = 1, phosphine oxide compounds comprised therein and to organic electroluminescent devices comprising such layers and compounds.
Metal-free phosphonation of heteroarene N-oxides with trialkyl phosphite at room temperature
Chen, Ming-Tao,You, Xia,Bai, Li-Gang,Luo, Qun-Li
supporting information, p. 3165 - 3169 (2017/04/21)
A new protocol is described for the conversion of heteroarene N-oxides to heteroarylphosphonates through in situ activation with bromotrichloromethane. The N-oxides of isoquinoline, quinoline, quinoxaline and 1,10-phenanthroline were fast transformed into the corresponding heteroarylphosphonates in up to 92% yield under mild conditions in the absence of solvent and metal catalysts. The good functional group tolerance, low cost, feasibility of scale up, and wide availability of reagents make this method a prominent complement to the Hirao coupling.
Preparation method, intermediate and crystal form of spironolamine arylphosphine oxide
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Paragraph 0092-0096, (2017/08/30)
The invention discloses a preparation method and a crystal form of high-purity spironolamine arylphosphine oxide. The invention further discloses a method for preparing a compound shown as a formula (I) and an intermediate compound.
Spiro aryl phosphorus oxide or sulfide
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Paragraph 0188; 0189; 0190; 0191, (2016/10/08)
The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitor, and in particular discloses a compound shown in a formula (I) as an ALK inhibitor or a pharmaceutically acceptable salt thereof.
